Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(rac)-(7-(3,4-dimethoxybenzyl)-4,5-dihydrothieno[2,3-c]pyridin-6(7H)-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone
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 PubChem ID
CID: 127040734
Canonical SMILES
COc1ccc(CC2c3sccc3CCN2C(=O)c2cc(C)ccc2-n2nccn2)cc1OC
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Compound Formula C26H26N4O3S
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 131 nM
   TI
   LI
   LO
   TS