Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(5,6-dimethoxypyridin-2-yl)methyl]-5-(5-methylpyridin-3-yl)-2-phenylbenzamide
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 PubChem ID
CID: 46195690
SID: 96049497
Canonical SMILES
COc1ccc(CNC(=O)c2cc(ccc2-c2ccccc2)-c2cncc(C)c2)nc1OC
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Compound Formula C27H25N3O3
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 1542 nM
   TI
   LI
   LO
   TS
2
Ki = 1000 nM
   TI
   LI
   LO
   TS