Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8680275, 156
    Show/Hide
 PubChem ID
CID: 67116774
Canonical SMILES
COc1ccc(-c2ncccn2)c(C(=O)N2CC[C@H]3CN([C@H]3C2)c2nc(C)cc(C)n2)c1F
    Show/Hide
Compound Formula C24H25FN6O2
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 860 nM
   TI
   LI
   LO
   TS