Brief Information of the Compound and Protein
Compound Name
(2S)-1-(3,4-dihydro-1H-isoquinolin-2-yl)-2-[2-(furan-2-yl)quinazolin-4-yl]sulfanylpropan-1-one
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PubChem ID
CID: 40102854
Canonical SMILES
C[C@H](Sc1nc(nc2ccccc12)-c1ccco1)C(=O)N1CCc2ccccc2C1
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Compound Formula C24H21N3O2S
Compound Structure
Protein Name
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 8912.51 nM
   TI
   LI
   LO
   TS