Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl 1-methyl-2-[2-[(3R,6R)-6-methyl-1-[2-(triazol-2-yl)benzoyl]piperidin-3-yl]-1,3-oxazol-4-yl]cyclopropane-1-carboxylate
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Canonical SMILES
COC(=O)C1(C)CC1c1coc(n1)[C@@H]1CC[C@@H](C)N(C1)C(=O)c1ccccc1-n1nccn1
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Compound Formula C24H27N5O4
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1080 nM
   TI
   LI
   LO
   TS