Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[[(2S,4R)-4-methoxy-1-(2-methyl-4-phenyl-1,3-thiazole-5-carbonyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
    Show/Hide
 PubChem ID
CID: 70683744
Canonical SMILES
CO[C@@H]1CCN([C@H](CNC(=O)c2cccc3cccnc23)C1)C(=O)c1sc(C)nc1-c1ccccc1
    Show/Hide
Compound Formula C28H28N4O3S
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 390 nM
   TI
   LI
   LO
   TS