Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1R,2S)-2-[[3-methoxy-4-(methoxymethyl)phenoxy]methyl]-2-phenyl-N-pyridin-2-ylcyclopropane-1-carboxamide
    Show/Hide
 PubChem ID
CID: 118716941
Canonical SMILES
COCc1ccc(OC[C@]2(C[C@H]2C(=O)Nc2ccccn2)c2ccccc2)cc1OC
    Show/Hide
Compound Formula C25H26N2O4
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 772 nM
   TI
   LI
   LO
   TS