Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(2S)-1-[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]-3-methylbutan-2-yl]-N,5-dimethyl-2-(triazol-2-yl)benzamide
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 PubChem ID
CID: 118020504
Canonical SMILES
CC(C)[C@@H](Cn1ccc(n1)-c1ccc(F)cn1)N(C)C(=O)c1cc(C)ccc1-n1nccn1
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Compound Formula C24H26FN7O
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 61.5 nM
   TI
   LI
   LO
   TS