Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8680275, 122
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 PubChem ID
CID: 67116816
Canonical SMILES
Fc1ccc(C(=O)N2CC[C@H]3CN([C@H]3C2)c2nc3cc(Cl)ccc3o2)c(c1)-n1nccn1
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Compound Formula C22H18ClFN6O2
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 128 nM
   TI
   LI
   LO
   TS