Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-(3,5-dimethylpyrazol-1-yl)-4-N-phenyl-2-N-[(Z)-[(E)-4-phenylbut-3-en-2-ylidene]amino]-1,3,5-triazine-2,4-diamine
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 PubChem ID
CID: 6859582
Canonical SMILES
C\C(\C=C\c1ccccc1)=N\Nc1nc(Nc2ccccc2)nc(n1)-n1nc(C)cc1C
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Compound Formula C24H24N8
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 13300 nM
   TI
   LI
   LO
   TS
2
Ki = 7600 nM
   TI
   LI
   LO
   TS