Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[2-(4-amino-1,2,5-oxadiazol-3-yl)benzimidazol-1-yl]-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide
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 PubChem ID
CID: 1207917
Canonical SMILES
COc1ccc(CCNC(=O)Cn2c(nc3ccccc23)-c2nonc2N)cc1OC
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Compound Formula C21H22N6O4
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
IC50 = 11700 nM
   TI
   LI
   LO
   TS
2
Ki = 6700 nM
   TI
   LI
   LO
   TS
3
Ki = 13100 nM
   TI
   LI
   LO
   TS