Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N'-(2,5-dichlorophenyl)-2-hydroxy-2,2-bis(4-methylphenyl)acetohydrazide
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 PubChem ID
CID: 3119749
Canonical SMILES
Cc1ccc(cc1)C(O)(C(=O)NNc1cc(Cl)ccc1Cl)c1ccc(C)cc1
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Compound Formula C22H20Cl2N2O2
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
IC50 = 4800 nM
   TI
   LI
   LO
   TS
2
Ki = 2700 nM
   TI
   LI
   LO
   TS
3
Ki = 10300 nM
   TI
   LI
   LO
   TS