Brief Information of the Compound and Protein
Compound Name
(5R)-1-(3-chlorophenyl)-5-methyl-4-(naphthalene-1-carbonyl)piperazin-2-one
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PubChem ID
CID: 97127806
Canonical SMILES
C[C@@H]1CN(C(=O)CN1C(=O)c1cccc2ccccc12)c1cccc(Cl)c1
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Compound Formula C22H19ClN2O2
Compound Structure
Protein Name
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS