Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[5-(4-fluorophenyl)-2-methyl-1,3-thiazol-4-yl]-[(2S,6S)-2-methyl-6-[[[5-(trifluoromethyl)pyridin-2-yl]amino]methyl]piperidin-1-yl]methanone
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 PubChem ID
CID: 70681620
Canonical SMILES
C[C@H]1CCC[C@@H](CNc2ccc(cn2)C(F)(F)F)N1C(=O)c1nc(C)sc1-c1ccc(F)cc1
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Compound Formula C24H24F4N4OS
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 14 nM
   TI
   LI
   LO
   TS