Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(6R)-4-(benzenesulfonyl)-6-fluoro-N-phenyl-1-oxa-4,8-diazaspiro[4.5]decane-8-carboxamide
    Show/Hide
 PubChem ID
CID: 70687123
Canonical SMILES
F[C@@H]1CN(CCC11OCCN1S(=O)(=O)c1ccccc1)C(=O)Nc1ccccc1
    Show/Hide
Compound Formula C20H22FN3O4S
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 280 nM
   TI
   LI
   LO
   TS