Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenylcyclopropyl]-(6-fluoro-1H-benzimidazol-2-yl)methanone
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 PubChem ID
CID: 118716947
Canonical SMILES
COc1ccc(OC[C@]2(C[C@H]2C(=O)c2nc3cc(F)ccc3[nH]2)c2ccccc2)cc1OC
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Compound Formula C26H23FN2O4
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 106 nM
   TI
   LI
   LO
   TS