Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8680275, 88
    Show/Hide
 PubChem ID
CID: 52919816
SID: 123056912
Canonical SMILES
Cc1ccc(C(=O)N2CC[C@H]3CN([C@H]3C2)c2nc(C)cc(C)n2)c(n1)-n1ccnn1
    Show/Hide
Compound Formula C21H24N8O
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 8200 nM
   TI
   LI
   LO
   TS