Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[(2R,5R)-5-[4-(2-hydroxypropan-2-yl)-5-methyl-1,3-oxazol-2-yl]-2-methylpiperidin-1-yl]-[2-(triazol-2-yl)phenyl]methanone
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 PubChem ID
CID: 117859508
Canonical SMILES
C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1-n1nccn1)c1nc(c(C)o1)C(C)(C)O
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Compound Formula C22H27N5O3
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 815 nM
   TI
   LI
   LO
   TS