Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(1-ethyl-3-methyl-4-(4-(trifluoromethyl)benzyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
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 PubChem ID
CID: 46880451
Canonical SMILES
CCn1nc(C)c2C(Cc3ccc(cc3)C(F)(F)F)N(CCc12)C(C(=O)NC)c1ccccc1
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Compound Formula C26H29F3N4O
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 769 nM
   TI
   LI
   LO
   TS