Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)(4-(quinazolin-2-yl)-1,4-diazepan-1-yl)methanone
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 PubChem ID
CID: 24882716
SID: 50138462
Canonical SMILES
Cc1ccc(c(c1)C(=O)N1CCCN(CC1)c1ncc2ccccc2n1)-n1nccn1
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Compound Formula C23H23N7O
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
2
Ki = 1.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 29 nM
2 Ki = 1.2 nM