| Compound ID |
Compound Name |
Compound Formula |
|
CP0110239
|
4-(1H-imidazol-4-ylmethyl)piperidine
Show/Hide
|
C9H15N3
|
5
|
| 1 |
EC50 = 0.03981 nM
|
|
|
| 2 |
EC50 = 0.1259 nM
|
|
|
| 3 |
EC50 = 0.1318 nM
|
|
|
| 4 |
Ki = 0.4786 nM
|
|
|
| 5 |
Ki = 0.5012 nM
|
|
|
|
CP0214392
|
5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole
Show/Hide
|
C13H15IN2O
|
2
|
| 1 |
EC50 = 0.05012 nM
|
|
|
| 2 |
Ki = 0.631 nM
|
|
|
|
CP0449897
|
Beta-Methylhistamine
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|
C6H11N3
|
1
|
| 1 |
EC50 = 0.123 nM
|
|
|
|
CP0098027
|
2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide
Show/Hide
|
C6H10N4S
|
2
|
| 1 |
EC50 = 0.1259 nM
|
|
|
| 2 |
Ki = 1.585 nM
|
|
|
|
CP0376332
|
4-(1H-imidazol-5-ylmethyl)pyridine
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|
C9H9N3
|
4
|
| 1 |
EC50 = 0.1585 nM
|
|
|
| 2 |
EC50 = 0.182 nM
|
|
|
| 3 |
Ki = 0.7943 nM
|
|
|
| 4 |
Ki = 0.8511 nM
|
|
|
|
CP0376707
|
4-(1H-imidazol-5-ylmethyl)-1-methylpiperidine
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|
C10H17N3
|
2
|
| 1 |
EC50 = 0.3162 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0047136
|
(2R)-1-(1H-imidazol-5-yl)propan-2-amine
Show/Hide
|
C6H11N3
|
5
|
| 1 |
EC50 = 0.3162 nM
|
|
|
| 2 |
EC50 = 0.6761 nM
|
|
|
| 3 |
Ki = 0.8 nM
|
|
|
| 4 |
Ki = 4.365 nM
|
|
|
| 5 |
Ki = 6.31 nM
|
|
|
|
CP0220693
|
5-[[(3S)-pyrrolidin-3-yl]methyl]-1H-imidazole
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|
C8H13N3
|
2
|
| 1 |
EC50 = 0.389 nM
|
|
|
| 2 |
Ki = 1.413 nM
|
|
|
|
CP0061272
|
N(alpha)-Methylhistamine
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|
C6H11N3
|
2
|
| 1 |
EC50 = 0.3981 nM
|
|
|
| 2 |
Ki = 3.981 nM
|
|
|
|
CP0437516
|
Clobenprobit
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|
C15H19ClN4S
|
2
|
| 1 |
EC50 = 0.3981 nM
|
|
|
| 2 |
Ki = 2.512 nM
|
|
|
|
CP0437514
|
VUF 8328
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|
C7H12N4S
|
3
|
| 1 |
EC50 = 0.5012 nM
|
|
|
| 2 |
Ki = 2.512 nM
|
|
|
| 3 |
Ki = 3.162 nM
|
|
|
|
CP0185384
|
4-(1H-imidazol-5-yl)butan-1-amine
Show/Hide
|
C7H13N3
|
6
|
| 1 |
EC50 = 0.631 nM
|
|
|
| 2 |
EC50 = 5.012 nM
|
|
|
| 3 |
EC50 = 7.413 nM
|
|
|
| 4 |
Ki = 3.981 nM
|
|
|
| 5 |
Ki = 4.074 nM
|
|
|
| 6 |
Ki = 4.3 nM
|
|
|
|
CP0862267
|
[4-(1H-imidazol-4-yl)-butyl]-dimethyl-amine
Show/Hide
|
C9H17N3
|
2
|
| 1 |
EC50 = 1.259 nM
|
|
|
| 2 |
Ki = 3.162 nM
|
|
|
|
CP0099997
|
5-(pyrrolidin-3-ylmethyl)-1H-imidazole
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|
C8H13N3
|
2
|
| 1 |
EC50 = 1.318 nM
|
|
|
| 2 |
Ki = 3.631 nM
|
|
|
|
CP0227942
|
5-[[(3R)-pyrrolidin-3-yl]methyl]-1H-imidazole
Show/Hide
|
C8H13N3
|
2
|
| 1 |
EC50 = 2.089 nM
|
|
|
| 2 |
Ki = 5.248 nM
|
|
|
|
CP0049414
|
4-[1-(1H-imidazol-5-yl)ethenyl]piperidine
Show/Hide
|
C10H15N3
|
2
|
| 1 |
EC50 = 2.344 nM
|
|
|
| 2 |
Ki = 3.981 nM
|
|
|
|
CP0208579
|
4( 5)-( 5-aminopenty1)-lH-imidazole
Show/Hide
|
C8H15N3
|
5
|
| 1 |
EC50 = 2.344 nM
|
|
|
| 2 |
EC50 = 3.981 nM
|
|
|
| 3 |
EC50 = 5.012 nM
|
|
|
| 4 |
Ki = 5.012 nM
|
|
|
| 5 |
Ki = 5.129 nM
|
|
|
|
CP0445709
|
4-(1H-imidazol-5-ylmethylidene)-1-methylpiperidine
Show/Hide
|
C10H15N3
|
2
|
| 1 |
EC50 = 2.512 nM
|
|
|
| 2 |
Ki = 6.31 nM
|
|
|
|
CP0207500
|
4-(1H-imidazol-5-ylmethylidene)piperidine
Show/Hide
|
C9H13N3
|
3
|
| 1 |
EC50 = 3.162 nM
|
|
|
| 2 |
Ki = 5.888 nM
|
|
|
| 3 |
Ki = 6.31 nM
|
|
|
|
CP0213459
|
3-(1H-imidazol-4-yl)propylphenylmethyl ether
Show/Hide
|
C13H16N2O
|
2
|
| 1 |
EC50 = 3.162 nM
|
|
|
| 2 |
Ki = 12.59 nM
|
|
|
|
CP0375934
|
1-ethyl-4-(1H-imidazol-5-ylmethyl)piperidine
Show/Hide
|
C11H19N3
|
2
|
| 1 |
EC50 = 3.981 nM
|
|
|
| 2 |
Ki = 15.85 nM
|
|
|
|
CP0499215
|
1-cyclohexyl-4-(1H-imidazol-5-ylmethyl)piperidine
Show/Hide
|
C15H25N3
|
2
|
| 1 |
EC50 = 3.981 nM
|
|
|
| 2 |
Ki = 15.85 nM
|
|
|
|
CP0036920
|
2-(1H-imidazol-4-yl)ethan-1-amine
Show/Hide
|
C5H9N3
|
5
|
| 1 |
EC50 = 4.074 nM
|
|
|
| 2 |
EC50 = 5.012 nM
|
|
|
| 3 |
EC50 = 9.772 nM
|
|
|
| 4 |
Ki = 9.333 nM
|
|
|
| 5 |
Ki = 10 nM
|
|
|
|
CP0875453
|
butyl-[5-(1H-imidazol-4-yl)-pentyl]-amine
Show/Hide
|
C12H23N3
|
2
|
| 1 |
EC50 = 5.012 nM
|
|
|
| 2 |
Ki = 3.981 nM
|
|
|
|
CP0881153
|
butyl-[4-(1H-imidazol-4-yl)-butyl]-amine
Show/Hide
|
C11H21N3
|
2
|
| 1 |
EC50 = 5.012 nM
|
|
|
| 2 |
Ki = 6.31 nM
|
|
|
|
CP0047517
|
(1S,2S)-2-(1H-Imidazol-4-yl)-cyclopropylamine
Show/Hide
|
C6H9N3
|
2
|
| 1 |
EC50 = 5.888 nM
|
|
|
| 2 |
Ki = 9.333 nM
|
|
|
|
CP0846869
|
4-[2-(3H-Imidazol-4-yl)-ethyl]-pyridine
Show/Hide
|
C10H11N3
|
2
|
| 1 |
EC50 = 6.761 nM
|
|
|
| 2 |
Ki = 6.918 nM
|
|
|
|
CP0497954
|
4-(1H-imidazol-5-ylmethyl)-1-propan-2-ylpiperidine
Show/Hide
|
C12H21N3
|
2
|
| 1 |
EC50 = 7.943 nM
|
|
|
| 2 |
Ki = 63.1 nM
|
|
|
|
CP0500577
|
4-(1H-imidazol-5-ylmethyl)-1-(2-phenylethyl)piperidine
Show/Hide
|
C17H23N3
|
2
|
| 1 |
EC50 = 7.943 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
|
CP0846757
|
[5-(1H-imidazol-4-yl)-pentyl]-isobutyl-amine
Show/Hide
|
C12H23N3
|
2
|
| 1 |
EC50 = 7.943 nM
|
|
|
| 2 |
Ki = 1.585 nM
|
|
|
|
CP0049822
|
4-[3-(1H-imidazol-5-yl)propyl]piperidine
Show/Hide
|
C11H19N3
|
3
|
| 1 |
EC50 = 8.318 nM
|
|
|
| 2 |
Kd = 7.943 nM
|
|
|
| 3 |
Ki = 4.467 nM
|
|
|
|
CP0875456
|
[5-(1H-imidazol-4-yl)-pentyl]-propyl-amine
Show/Hide
|
C11H21N3
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
Ki = 5.012 nM
|
|
|
|
CP0376706
|
(2S)-1-(1H-imidazol-5-yl)propan-2-amine
Show/Hide
|
C6H11N3
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
Ki = 63.1 nM
|
|
|
|
CP0216996
|
4-[2-(1H-imidazol-5-yl)ethyl]piperidine
Show/Hide
|
C10H17N3
|
3
|
| 1 |
EC50 = 12.59 nM
|
|
|
| 2 |
EC50 = 13.18 nM
|
|
|
| 3 |
Ki = 19.95 nM
|
|
|
|
CP0381722
|
4-(1H-imidazol-5-ylmethylidene)-1-(2-phenylethyl)piperidine
Show/Hide
|
C17H21N3
|
2
|
| 1 |
EC50 = 15.85 nM
|
|
|
| 2 |
Ki = 63.1 nM
|
|
|
|
CP0494975
|
1-benzyl-4-(1H-imidazol-5-ylmethyl)piperidine
Show/Hide
|
C16H21N3
|
2
|
| 1 |
EC50 = 15.85 nM
|
|
|
| 2 |
Ki = 50.12 nM
|
|
|
|
CP0889371
|
[4-(1H-Imidazol-4-yl)butyl]propylamine
Show/Hide
|
C10H19N3
|
2
|
| 1 |
EC50 = 15.85 nM
|
|
|
| 2 |
Ki = 7.943 nM
|
|
|
|
CP0108124
|
[2-(1H-imidazol-5-yl)cyclopropyl]methanamine
Show/Hide
|
C7H11N3
|
2
|
| 1 |
EC50 = 19.5 nM
|
|
|
| 2 |
Ki = 35.48 nM
|
|
|
|
CP0845651
|
4-[3-(3H-Imidazol-4-yl)-propyl]-pyridine
Show/Hide
|
C11H13N3
|
2
|
| 1 |
EC50 = 19.5 nM
|
|
|
| 2 |
Ki = 15.49 nM
|
|
|
|
CP0379556
|
VUF5300
Show/Hide
|
C13H23N3
|
2
|
| 1 |
EC50 = 19.95 nM
|
|
|
| 2 |
Ki = 7.943 nM
|
|
|
|
CP0494960
|
1-ethyl-4-(1H-imidazol-5-ylmethylidene)piperidine
Show/Hide
|
C11H17N3
|
2
|
| 1 |
EC50 = 25.12 nM
|
|
|
| 2 |
Ki = 50.12 nM
|
|
|
|
CP0854866
|
ethyl[4-(1H-imidazol-4-yl)butyl]amine
Show/Hide
|
C9H17N3
|
2
|
| 1 |
EC50 = 25.12 nM
|
|
|
| 2 |
Ki = 25.12 nM
|
|
|
|
CP0861251
|
3-[3-(3H-Imidazol-4-yl)-propyl]-pyridine
Show/Hide
|
C11H13N3
|
2
|
| 1 |
EC50 = 30.9 nM
|
|
|
| 2 |
Ki = 33.11 nM
|
|
|
|
CP0376170
|
4-(1H-imidazol-5-ylmethyl)-1-(3-phenylpropyl)piperidine
Show/Hide
|
C18H25N3
|
2
|
| 1 |
EC50 = 31.62 nM
|
|
|
| 2 |
Ki = 39.81 nM
|
|
|
|
CP0379557
|
VUF5207
Show/Hide
|
C10H19N3
|
2
|
| 1 |
EC50 = 31.62 nM
|
|
|
| 2 |
Ki = 15.85 nM
|
|
|
|
CP0875448
|
1-[4-(1H-imidazol-4-yl)-butyl]-piperidine
Show/Hide
|
C12H21N3
|
2
|
| 1 |
EC50 = 31.62 nM
|
|
|
| 2 |
Ki = 19.95 nM
|
|
|
|
CP0881157
|
4-(5-pyrrolidin-1-yl-pentyl)-1H-imidazole
Show/Hide
|
C12H21N3
|
2
|
| 1 |
EC50 = 31.62 nM
|
|
|
| 2 |
Ki = 31.62 nM
|
|
|
|
CP0037936
|
6-(1H-imidazol-5-yl)hexan-1-amine
Show/Hide
|
C9H17N3
|
2
|
| 1 |
EC50 = 33.11 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
|
CP0380345
|
3-((1H-imidazol-4-yl)methyl)pyridine
Show/Hide
|
C9H9N3
|
2
|
| 1 |
EC50 = 38.9 nM
|
|
|
| 2 |
Ki = 52.48 nM
|
|
|
|
CP0848089
|
4-(4-pyrrolidin-1-yl-butyl)-1H-imidazole
Show/Hide
|
C11H19N3
|
2
|
| 1 |
EC50 = 39.81 nM
|
|
|
| 2 |
Ki = 39.81 nM
|
|
|
|
CP0108024
|
3-(1H-imidazol-5-yl)propan-1-amine
Show/Hide
|
C6H11N3
|
4
|
| 1 |
EC50 = 39.81 nM
|
|
|
| 2 |
EC50 = 42.66 nM
|
|
|
| 3 |
Ki = 48.98 nM
|
|
|
| 4 |
Ki = 50.12 nM
|
|
|
|
CP0130853
|
Imifuramine
Show/Hide
|
C8H13N3O
|
3
|
| 1 |
EC50 = 39.81 nM
|
|
|
| 2 |
EC50 = 44.67 nM
|
|
|
| 3 |
Ki = 251.19 nM
|
|
|
|
CP0684017
|
3-((1H-imidazol-5-yl)methyl)piperidine
Show/Hide
|
C9H15N3
|
2
|
| 1 |
EC50 = 48.98 nM
|
|
|
| 2 |
Ki = 67.61 nM
|
|
|
|
CP0381417
|
4-[2-(1H-imidazol-5-yl)ethyl]-1-methylpiperidine
Show/Hide
|
C11H19N3
|
2
|
| 1 |
EC50 = 50.12 nM
|
|
|
| 2 |
Ki = 50.12 nM
|
|
|
|
CP0509668
|
1-cyclohexyl-4-(1H-imidazol-5-ylmethylidene)piperidine
Show/Hide
|
C15H23N3
|
2
|
| 1 |
EC50 = 50.12 nM
|
|
|
| 2 |
Ki = 31.62 nM
|
|
|
|
CP0878272
|
1-[4-(1H-imidazol-4-yl)-butyl]-azepane
Show/Hide
|
C13H23N3
|
2
|
| 1 |
EC50 = 50.12 nM
|
|
|
| 2 |
Ki = 39.81 nM
|
|
|
|
CP0883136
|
1-[5-(1H-imidazol-4-yl)-pentyl]-azepane
Show/Hide
|
C14H25N3
|
2
|
| 1 |
EC50 = 50.12 nM
|
|
|
| 2 |
Ki = 15.85 nM
|
|
|
|
CP0114981
|
(1R,2R)-2-(1H-Imidazol-4-yl)-cyclopropylamine
Show/Hide
|
C6H9N3
|
2
|
| 1 |
EC50 = 57.54 nM
|
|
|
| 2 |
Ki = 67.61 nM
|
|
|
|
CP0421390
|
4-(1H-imidazol-5-ylmethylidene)-1-propan-2-ylpiperidine
Show/Hide
|
C12H19N3
|
2
|
| 1 |
EC50 = 63.1 nM
|
|
|
| 2 |
Ki = 63.1 nM
|
|
|
|
CP0509669
|
1-benzyl-4-(1H-imidazol-5-ylmethylidene)piperidine
Show/Hide
|
C16H19N3
|
2
|
| 1 |
EC50 = 79.43 nM
|
|
|
| 2 |
Ki = 398.11 nM
|
|
|
|
CP0348117
|
5-[(2R,5R)-5-(phenylmethoxymethyl)oxolan-2-yl]-1H-imidazole
Show/Hide
|
C15H18N2O2
|
3
|
| 1 |
EC50 = 91.2 nM
|
|
|
| 2 |
EC50 = 100 nM
|
|
|
| 3 |
Ki = 251.19 nM
|
|
|
|
CP0154610
|
[(2S,5S)-5-(1H-imidazol-5-yl)oxolan-2-yl]methanamine
Show/Hide
|
C8H13N3O
|
3
|
| 1 |
EC50 = 100 nM
|
|
|
| 2 |
EC50 = 104.71 nM
|
|
|
| 3 |
Ki = 199.53 nM
|
|
|
|
CP0288244
|
5-fluoro-4-methyl-2-(2-methyl-4-(3-((4aR,7aR)-tetrahydro-1H-pyrrolo[3,4-b]pyridin-6(2H,7H,7aH)-yl)propoxy)phenyl)-1H-benzo[d]imidazole
Show/Hide
|
C25H31FN4O
|
1
|
| 1 |
EC50 = 119 nM
|
|
|
|
CP0172969
|
5-[(2R,5S)-5-(phenylmethoxymethyl)oxolan-2-yl]-1H-imidazole
Show/Hide
|
C15H18N2O2
|
3
|
| 1 |
EC50 = 190.55 nM
|
|
|
| 2 |
EC50 = 199.53 nM
|
|
|
| 3 |
Ki = 316.23 nM
|
|
|
|
CP0430895
|
4-[2-(1H-imidazol-5-yl)ethyl]-1-propan-2-ylpiperidine
Show/Hide
|
C13H23N3
|
2
|
| 1 |
EC50 = 199.53 nM
|
|
|
| 2 |
Ki = 100 nM
|
|
|
|
CP0154225
|
[(2R,5R)-5-(1H-imidazol-5-yl)-2,5-dihydrofuran-2-yl]methanamine
Show/Hide
|
C8H11N3O
|
1
|
| 1 |
EC50 = 269.15 nM
|
|
|
|
CP0509667
|
1-cyclohexyl-4-[2-(1H-imidazol-5-yl)ethyl]piperidine
Show/Hide
|
C16H27N3
|
2
|
| 1 |
EC50 = 316.23 nM
|
|
|
| 2 |
Ki = 158.49 nM
|
|
|
|
CP0202795
|
2-(diaminomethylideneamino)ethyl carbamimidothioate
Show/Hide
|
C4H11N5S
|
2
|
| 1 |
EC50 = 316.23 nM
|
|
|
| 2 |
Ki = 1000 nM
|
|
|
|
CP0208773
|
2-[3-(1H-imidazol-5-yl)propyl]piperidine
Show/Hide
|
C11H19N3
|
2
|
| 1 |
EC50 = 323.59 nM
|
|
|
| 2 |
Ki = 93.33 nM
|
|
|
|
CP0860906
|
3-[2-(3H-Imidazol-4-yl)-ethyl]-pyridine
Show/Hide
|
C10H11N3
|
2
|
| 1 |
EC50 = 354.81 nM
|
|
|
| 2 |
Ki = 141.25 nM
|
|
|
|
CP0213380
|
5-(3-(4-(5-fluoro-4-methyl-1H-benzo[d]imidazol-2-yl)-3-methylphenoxy)propyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine
Show/Hide
|
C24H26FN5O
|
1
|
| 1 |
EC50 = 377 nM
|
|
|
|
CP0050043
|
3-[2-(1H-imidazol-5-yl)ethyl]piperidine
Show/Hide
|
C10H17N3
|
2
|
| 1 |
EC50 = 512.86 nM
|
|
|
| 2 |
Ki = 181.97 nM
|
|
|
|
CP0185528
|
3-[3-(1H-imidazol-5-yl)propyl]piperidine
Show/Hide
|
C11H19N3
|
2
|
| 1 |
EC50 = 512.86 nM
|
|
|
| 2 |
Ki = 83.18 nM
|
|
|
|
CP0441099
|
2-((1H-imidazol-4-yl)methyl)pyridine
Show/Hide
|
C9H9N3
|
2
|
| 1 |
EC50 = 602.56 nM
|
|
|
| 2 |
Ki = 588.84 nM
|
|
|
|
CP0182141
|
[(2S,5R)-5-(1H-imidazol-5-yl)oxolan-2-yl]methanamine
Show/Hide
|
C8H13N3O
|
3
|
| 1 |
EC50 = 776.25 nM
|
|
|
| 2 |
EC50 = 794.33 nM
|
|
|
| 3 |
Ki = 1995.26 nM
|
|
|
|
CP0212820
|
2-(1H-imidazol-5-ylmethyl)piperidine
Show/Hide
|
C9H15N3
|
2
|
| 1 |
EC50 = 794.33 nM
|
|
|
| 2 |
Ki = 1148.15 nM
|
|
|
|
CP0097151
|
[(2R,5S)-5-(1H-imidazol-5-yl)oxolan-2-yl]methanamine
Show/Hide
|
C8H13N3O
|
3
|
| 1 |
EC50 = 794.33 nM
|
|
|
| 2 |
EC50 = 812.83 nM
|
|
|
| 3 |
Ki = 1584.89 nM
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|
|
CP0847382
|
2-[3-(3H-Imidazol-4-yl)-propyl]-pyridine
Show/Hide
|
C11H13N3
|
2
|
| 1 |
EC50 = 912.01 nM
|
|
|
| 2 |
Ki = 1047.13 nM
|
|
|
|
CP0041262
|
5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-indole
Show/Hide
|
C14H16ClN3O
|
2
|
| 1 |
EC50 = 1000 nM
|
|
|
| 2 |
Ki = 1995.26 nM
|
|
|
|
CP0654709
|
(5-Chloro-1H-indol-2-yl)-(1-methyl-piperidin-4-yl)-methanol
Show/Hide
|
C15H19ClN2O
|
2
|
| 1 |
EC50 = 1000 nM
|
|
|
| 2 |
Ki = 1584.89 nM
|
|
|
|
CP0783423
|
(5-Chloro-1H-indol-2-yl)-(1-methyl-piperidin-4-yl)-methanone
Show/Hide
|
C15H17ClN2O
|
2
|
| 1 |
EC50 = 1000 nM
|
|
|
| 2 |
Ki = 3162.28 nM
|
|
|
|
CP0845085
|
2-[2-(3H-Imidazol-4-yl)-ethyl]-pyridine
Show/Hide
|
C10H11N3
|
2
|
| 1 |
EC50 = 1348.96 nM
|
|
|
| 2 |
Ki = 1174.9 nM
|
|
|
|
CP0197119
|
4-(1H-imidazol-5-yl)-1,2,3,6-tetrahydropyridine
Show/Hide
|
C8H11N3
|
2
|
| 1 |
EC50 = 1513.56 nM
|
|
|
| 2 |
Ki = 4265.8 nM
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|
|
|
CP0193887
|
(5-Bromo-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H16BrN3O
|
2
|
| 1 |
EC50 = 1584.89 nM
|
|
|
| 2 |
Ki = 3162.28 nM
|
|
|
|
CP0244327
|
4-(1H-imidazol-5-yl)piperidine
Show/Hide
|
C8H13N3
|
2
|
| 1 |
EC50 = 1819.7 nM
|
|
|
| 2 |
Ki = 870.96 nM
|
|
|
|
CP0220690
|
1H-imidazol-5-yl(piperidin-4-yl)methanone
Show/Hide
|
C9H13N3O
|
2
|
| 1 |
EC50 = 2754.23 nM
|
|
|
| 2 |
Ki = 3890.45 nM
|
|
|
|
CP0100889
|
[(2S,5S)-5-(1H-imidazol-5-yl)-2,5-dihydrofuran-2-yl]methanamine
Show/Hide
|
C8H11N3O
|
1
|
| 1 |
EC50 = 2818.38 nM
|
|
|
|
CP0066043
|
(5-Chloro-1H-benzoimidazol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C13H15ClN4O
|
2
|
| 1 |
EC50 = 3162.28 nM
|
|
|
| 2 |
Ki = 3981.07 nM
|
|
|
|
CP0656487
|
5-Chloro-1H-benzoimidazole-2-carboxylic acid (2-dimethylamino-ethyl)-amide
Show/Hide
|
C12H15ClN4O
|
2
|
| 1 |
EC50 = 3162.28 nM
|
|
|
| 2 |
Ki = 25118.86 nM
|
|
|
|
CP0747120
|
(5-Chloro-1H-indol-2-yl)-piperidin-1-yl-methanone
Show/Hide
|
C14H15ClN2O
|
2
|
| 1 |
EC50 = 3162.28 nM
|
|
|
| 2 |
Ki = 6309.57 nM
|
|
|
|
CP0779431
|
(5-Iodo-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H16IN3O
|
2
|
| 1 |
EC50 = 3162.28 nM
|
|
|
| 2 |
Ki = 2511.89 nM
|
|
|
|
CP0100890
|
1-cyano-3-[[(2R,5R)-5-(1H-imidazol-5-yl)oxolan-2-yl]methyl]-2-methylguanidine
Show/Hide
|
C11H16N6O
|
3
|
| 1 |
EC50 = 3162.28 nM
|
|
|
| 2 |
Ki = 1995.26 nM
|
|
|
| 3 |
Ki = 2200 nM
|
|
|
|
CP0270460
|
3-[4-(5-fluoro-4-methyl-1H-benzimidazol-2-yl)-3-methylphenoxy]-N-[2-(1H-imidazol-5-yl)ethyl]propan-1-amine
Show/Hide
|
C23H26FN5O
|
1
|
| 1 |
EC50 = 9000 nM
|
|
|
|
CP0309840
|
5-[(2S,5S)-5-(phenylmethoxymethyl)oxolan-2-yl]-1H-imidazole
Show/Hide
|
C15H18N2O2
|
3
|
| 1 |
EC50 = 9549.93 nM
|
|
|
| 2 |
EC50 = 10000 nM
|
|
|
| 3 |
Ki = 10000 nM
|
|
|
|
CP0122622
|
5-[(2S,5R)-5-(phenylmethoxymethyl)oxolan-2-yl]-1H-imidazole
Show/Hide
|
C15H18N2O2
|
3
|
| 1 |
EC50 = 9772.37 nM
|
|
|
| 2 |
EC50 = 10000 nM
|
|
|
| 3 |
Ki = 6309.57 nM
|
|
|
|
CP0279022
|
1-cyano-3-[[(2S,5R)-5-(1H-imidazol-5-yl)oxolan-2-yl]methyl]-2-methylguanidine
Show/Hide
|
C11H16N6O
|
3
|
| 1 |
EC50 = 10000 nM
|
|
|
| 2 |
EC50 = 10232.93 nM
|
|
|
| 3 |
Ki = 6309.57 nM
|
|
|
|
CP0055652
|
[(2S,5R)-5-(1H-imidazol-5-yl)-2,5-dihydrofuran-2-yl]methanamine
Show/Hide
|
C8H11N3O
|
1
|
| 1 |
EC50 = 26915.35 nM
|
|
|
|
CP0195654
|
1-cyano-3-[[(2S,5S)-5-(1H-imidazol-5-yl)oxolan-2-yl]methyl]-2-methylguanidine
Show/Hide
|
C11H16N6O
|
3
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
EC50 < 100000 nM
|
|
|
| 3 |
Ki = 19952.62 nM
|
|
|
|
CP0391089
|
1-benzyl-4-[2-(1H-imidazol-5-yl)ethyl]piperidine
Show/Hide
|
C17H23N3
|
2
|
| 1 |
EC50 < 10000 nM
|
|
|
| 2 |
Ki = 79.43 nM
|
|
|
|
CP0442272
|
1-ethyl-4-[2-(1H-imidazol-5-yl)ethyl]piperidine
Show/Hide
|
C12H21N3
|
2
|
| 1 |
EC50 < 10000 nM
|
|
|
| 2 |
Ki = 63.1 nM
|
|
|
|
CP0486026
|
4-[2-(1H-imidazol-5-yl)ethyl]-1-(2-phenylethyl)piperidine
Show/Hide
|
C18H25N3
|
2
|
| 1 |
EC50 < 10000 nM
|
|
|
| 2 |
Ki = 39.81 nM
|
|
|
|
CP0049208
|
2-[2-(1H-imidazol-5-yl)ethyl]piperidine
Show/Hide
|
C10H17N3
|
2
|
| 1 |
EC50 < 10000 nM
|
|
|
| 2 |
Ki = 2818.38 nM
|
|
|
|
CP0038430
|
[(2R,5S)-5-(1H-imidazol-5-yl)-2,5-dihydrofuran-2-yl]methanamine
Show/Hide
|
C8H11N3O
|
1
|
| 1 |
EC50 < 100000 nM
|
|
|
|
CP0424833
|
VUF5202
Show/Hide
|
C15H20ClN3
|
2
|
| 1 |
IC50 = 1.259 nM
|
|
|
| 2 |
Ki = 2.512 nM
|
|
|
|
CP0381534
|
4-(1H-imidazol-5-yl)-N-(2-methylpropyl)butan-1-amine
Show/Hide
|
C11H21N3
|
2
|
| 1 |
IC50 = 7.943 nM
|
|
|
| 2 |
Ki = 3.162 nM
|
|
|
|
CP0393912
|
N-[5-(1H-imidazol-5-yl)pentyl]cycloheptanamine
Show/Hide
|
C15H27N3
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
Ki = 3.162 nM
|
|
|
|
CP0432714
|
VUF4903
Show/Hide
|
C14H25N3
|
2
|
| 1 |
IC50 = 12.59 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
|
CP0453280
|
VUF4904
Show/Hide
|
C11H21N3
|
2
|
| 1 |
IC50 = 39.81 nM
|
|
|
| 2 |
Ki = 12.59 nM
|
|
|
|
CP0438698
|
1-[[3-(4-piperidin-1-ylbut-1-ynyl)phenyl]methyl]piperidine
Show/Hide
|
C21H30N2
|
2
|
| 1 |
Kd = 0.08128 nM
|
|
|
| 2 |
Ki = 0.7762 nM
|
|
|
|
CP0106703
|
1-((2R,4S)-2-(4-cyclobutyl-1,4-diazepane-1-carbonyl)-4-(4-fluorophenoxy)pyrrolidin-1-yl)ethanone
Show/Hide
|
C22H30FN3O3
|
1
|
| 1 |
Kd = 0.1349 nM
|
|
|
|
CP0056575
|
1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piperidine
Show/Hide
|
C20H32N2O
|
6
|
| 1 |
Kd = 0.1445 nM
|
|
|
| 2 |
Kd = 0.8318 nM
|
|
|
| 3 |
Ki = 0.4 nM
|
|
|
| 4 |
Ki = 0.5754 nM
|
|
|
| 5 |
Ki = 0.6 nM
|
|
|
| 6 |
Ki = 0.97 nM
|
|
|
|
CP0384614
|
4-cyclopentyl-2-((4-(piperidin-1-ylmethyl)phenoxy)methyl)morpholine
Show/Hide
|
C22H34N2O2
|
2
|
| 1 |
Kd = 0.1479 nM
|
|
|
| 2 |
Ki = 2.5 nM
|
|
|
|
CP0401512
|
1-(4-(4-(piperidin-1-ylmethyl)phenyl)but-3-ynyl)piperidine
Show/Hide
|
C21H30N2
|
2
|
| 1 |
Kd = 0.1479 nM
|
|
|
| 2 |
Ki = 0.5129 nM
|
|
|
|
CP0879187
|
Cyclohexyl-[4-(3-piperidin-1-yl-propoxy)-benzyl]-amine
Show/Hide
|
C21H34N2O
|
2
|
| 1 |
Kd = 0.195 nM
|
|
|
| 2 |
Ki = 0.5129 nM
|
|
|
|
CP0040569
|
1-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperidin-4-ol
Show/Hide
|
C20H32N2O2
|
2
|
| 1 |
Kd = 0.2291 nM
|
|
|
| 2 |
Ki = 0.7413 nM
|
|
|
|
CP0056261
|
(1-isopropylpiperidin-4-yl)(4-(piperidin-1-ylmethyl)phenyl)methanone
Show/Hide
|
C20H31N3O
|
3
|
| 1 |
Kd = 0.2399 nM
|
|
|
| 2 |
Ki = 0.8 nM
|
|
|
| 3 |
Ki = 1.3 nM
|
|
|
|
CP0400799
|
(4-cyclobutyl-1,4-diazepan-1-yl)(6-phenoxypyridin-3-yl)methanone
Show/Hide
|
C21H25N3O2
|
2
|
| 1 |
Kd = 0.2692 nM
|
|
|
| 2 |
Ki = 4.4 nM
|
|
|
|
CP0514095
|
(5-(3,4-dichlorophenoxy)pyridin-2-yl)(4-isopropyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C20H23Cl2N3O2
|
2
|
| 1 |
Kd = 0.309 nM
|
|
|
| 2 |
Ki = 1.5 nM
|
|
|
|
CP0115802
|
1-((2R,4S)-2-(4-cyclobutyl-1,4-diazepane-1-carbonyl)-4-(3-fluorophenoxy)pyrrolidin-1-yl)ethanone
Show/Hide
|
C22H30FN3O3
|
1
|
| 1 |
Kd = 0.3162 nM
|
|
|
|
CP0441522
|
4-cyclopentyl-2-((4-(pyrrolidin-1-ylmethyl)phenoxy)methyl)morpholine
Show/Hide
|
C21H32N2O2
|
2
|
| 1 |
Kd = 0.3311 nM
|
|
|
| 2 |
Ki = 2.2 nM
|
|
|
|
CP0477738
|
(4-cyclobutyl-1,4-diazepan-1-yl)(6-(phenylthio)pyridin-3-yl)methanone
Show/Hide
|
C21H25N3OS
|
2
|
| 1 |
Kd = 0.3311 nM
|
|
|
| 2 |
Ki = 2.3 nM
|
|
|
|
CP0516422
|
(4-cyclobutyl-1,4-diazepan-1-yl)(6-(4-fluorophenylthio)pyridin-3-yl)methanone
Show/Hide
|
C21H24FN3OS
|
2
|
| 1 |
Kd = 0.3311 nM
|
|
|
| 2 |
Ki = 29 nM
|
|
|
|
CP0460179
|
5-Piperidin-1-ylmethyl-2-(3-piperidin-1-yl-propoxy)-pyridine
Show/Hide
|
C19H31N3O
|
2
|
| 1 |
Kd = 0.3467 nM
|
|
|
| 2 |
Ki = 0.7 nM
|
|
|
|
CP0446007
|
(S)-4-cyclopentyl-2-((4-(morpholinomethyl)phenoxy)methyl)morpholine
Show/Hide
|
C21H32N2O3
|
2
|
| 1 |
Kd = 0.3802 nM
|
|
|
| 2 |
Ki = 1.9 nM
|
|
|
|
CP0046809
|
(4-cyclobutyl-1,4-diazepan-1-yl)(6-(4-fluorophenoxy)pyridin-3-yl)methanone
Show/Hide
|
C21H24FN3O2
|
2
|
| 1 |
Kd = 0.3802 nM
|
|
|
| 2 |
Ki = 1.4 nM
|
|
|
|
CP0265410
|
(4-cyclobutyl-1,4-diazepan-1-yl)(6-(3-fluorophenoxy)pyridin-3-yl)methanone
Show/Hide
|
C21H24FN3O2
|
2
|
| 1 |
Kd = 0.3981 nM
|
|
|
| 2 |
Ki = 4.1 nM
|
|
|
|
CP0125374
|
3-(5-(4-cyclobutyl-1,4-diazepane-1-carbonyl)pyridin-2-yloxy)benzonitrile
Show/Hide
|
C22H24N4O2
|
2
|
| 1 |
Kd = 0.4074 nM
|
|
|
| 2 |
Ki = 1.8 nM
|
|
|
|
CP0499738
|
2-Piperdin-1-ylmethyl-5-(3-piperdin-1-yl-propoxy)-pyridine
Show/Hide
|
C19H31N3O
|
2
|
| 1 |
Kd = 0.4169 nM
|
|
|
| 2 |
Ki = 0.9 nM
|
|
|
|
CP0110803
|
4-(4-(1-isopropylpiperidin-4-yloxy)benzyl)morpholine
Show/Hide
|
C19H30N2O2
|
2
|
| 1 |
Kd = 0.4786 nM
|
|
|
| 2 |
Ki = 2.1 nM
|
|
|
|
CP0095277
|
4-(3-(4-(piperidin-1-yl)but-1-ynyl)benzyl)morpholine
Show/Hide
|
C20H28N2O
|
5
|
| 1 |
Kd = 0.4898 nM
|
|
|
| 2 |
Kd = 0.6026 nM
|
|
|
| 3 |
Ki = 0.8 nM
|
|
|
| 4 |
Ki = 1 nM
|
|
|
| 5 |
Ki = 1.175 nM
|
|
|
|
CP0503187
|
(4-Isopropyl-piperazin-1-yl)-(5-piperidin-1-ylmethylpyridin-2-yl)-methanone
Show/Hide
|
C19H30N4O
|
2
|
| 1 |
Kd = 0.4898 nM
|
|
|
| 2 |
Ki = 1.5 nM
|
|
|
|
CP0486358
|
N,N-dimethyl-2-[4-(3-piperidin-1-ylpropoxy)phenyl]ethanamine
Show/Hide
|
C18H30N2O
|
2
|
| 1 |
Kd = 0.5012 nM
|
|
|
| 2 |
Ki = 0.5 nM
|
|
|
|
CP0115796
|
1-((2R,4S)-2-(4-cyclobutyl-1,4-diazepane-1-carbonyl)-4-(thiophen-3-yloxy)pyrrolidin-1-yl)ethanone
Show/Hide
|
C20H29N3O3S
|
1
|
| 1 |
Kd = 0.5248 nM
|
|
|
|
CP0325312
|
((2R,4S)-4-(3-chlorophenoxy)pyrrolidin-2-yl)(4-cyclobutyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C20H28ClN3O2
|
1
|
| 1 |
Kd = 0.5248 nM
|
|
|
|
CP0894624
|
4-[4-(3-Piperidin-1-yl-propoxy)-benzyl]-morpholine
Show/Hide
|
C19H30N2O2
|
2
|
| 1 |
Kd = 0.537 nM
|
|
|
| 2 |
Ki = 0.871 nM
|
|
|
|
CP0438770
|
(4-cyclobutyl-1,4-diazepan-1-yl)(5-(2-fluorophenoxy)pyridin-2-yl)methanone
Show/Hide
|
C21H24FN3O2
|
2
|
| 1 |
Kd = 0.537 nM
|
|
|
| 2 |
Ki = 4.3 nM
|
|
|
|
CP0374240
|
(4-cyclobutyl-1,4-diazepan-1-yl)(6-(3,4-dichlorophenoxy)pyridin-3-yl)methanone
Show/Hide
|
C21H23Cl2N3O2
|
2
|
| 1 |
Kd = 0.5495 nM
|
|
|
| 2 |
Ki = 7.6 nM
|
|
|
|
CP0159421
|
5-(3-cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy)-N-methylpyrazine-2-carboxamide
Show/Hide
|
C20H24N4O2
|
2
|
| 1 |
Kd = 0.5495 nM
|
|
|
| 2 |
Ki = 0.21 nM
|
|
|
|
CP0459511
|
(4-Isopropyl-piperazin-1-yl)-(5-piperidin-1-ylmethylpyrazin-2-yl)-methanone
Show/Hide
|
C18H29N5O
|
2
|
| 1 |
Kd = 0.5623 nM
|
|
|
| 2 |
Ki = 1.1 nM
|
|
|
|
CP0465925
|
(4-Isopropyl-piperazin-1-yl)-(5-piperidin-1-ylmethylfuran-2-yl)-methanone
Show/Hide
|
C18H29N3O2
|
2
|
| 1 |
Kd = 0.5754 nM
|
|
|
| 2 |
Ki = 3.4 nM
|
|
|
|
CP0246919
|
(6-(4-chlorophenoxy)pyridin-3-yl)(4-cyclobutyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C21H24ClN3O2
|
2
|
| 1 |
Kd = 0.6026 nM
|
|
|
| 2 |
Ki = 59 nM
|
|
|
|
CP0203171
|
N,N-diethyl-3-[(6-methyl-8-phenyl-7,8-dihydro-5H-2,6-naphthyridin-3-yl)oxy]propan-1-amine
Show/Hide
|
C22H31N3O
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2
|
| 1 |
Kd = 0.6607 nM
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| 2 |
Ki = 4 nM
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CP0158344
|
4-((3S,5R)-5-(4-cyclopentyl-1,4-diazepane-1-carbonyl)pyrrolidin-3-yloxy)benzonitrile
Show/Hide
|
C22H30N4O2
|
1
|
| 1 |
Kd = 0.7079 nM
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CP0144386
|
4-phenyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
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C22H29N3O
|
2
|
| 1 |
Kd = 0.7244 nM
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| 2 |
Ki = 1 nM
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CP0298758
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(4-cyclobutyl-1,4-diazepan-1-yl)((2R,4S)-4-(4-fluorophenoxy)-1-methylpyrrolidin-2-yl)methanone
Show/Hide
|
C21H30FN3O2
|
1
|
| 1 |
Kd = 0.7413 nM
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CP0227590
|
(4-Isopropyl-piperazin-1-yl)-(6-piperidin-1-ylmethylpyridin-3-yl)-methanone
Show/Hide
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C19H30N4O
|
2
|
| 1 |
Kd = 0.8128 nM
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| 2 |
Ki = 1.1 nM
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CP0333672
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(6-(3-chlorophenoxy)pyridin-3-yl)(4-cyclobutyl-1,4-diazepan-1-yl)methanone
Show/Hide
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C21H24ClN3O2
|
2
|
| 1 |
Kd = 0.871 nM
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| 2 |
Ki = 1 nM
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CP0441524
|
4-cyclopentyl-2-((4-(morpholinomethyl)phenoxy)methyl)morpholine
Show/Hide
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C21H32N2O3
|
2
|
| 1 |
Kd = 0.955 nM
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| 2 |
Ki = 3.6 nM
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CP0228017
|
((2R,4S)-4-(4-chlorophenoxy)pyrrolidin-2-yl)(4-cyclobutyl-1,4-diazepan-1-yl)methanone
Show/Hide
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C20H28ClN3O2
|
1
|
| 1 |
Kd = 0.955 nM
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CP0082416
|
4-(2-fluorophenyl)-2-methyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C23H30FN3O
|
2
|
| 1 |
Kd = 1.047 nM
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| 2 |
Ki = 2 nM
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CP0145914
|
4-(2-chlorophenyl)-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C22H28ClN3O
|
2
|
| 1 |
Kd = 1.047 nM
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| 2 |
Ki = 1 nM
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CP0262053
|
((2R,4S)-4-(4-chloro-3-methylphenoxy)pyrrolidin-2-yl)(4-cyclobutyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C21H30ClN3O2
|
1
|
| 1 |
Kd = 1.148 nM
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CP0325311
|
(4-cyclobutyl-1,4-diazepan-1-yl)((2R,4S)-4-(4-(trifluoromethyl)phenoxy)pyrrolidin-2-yl)methanone
Show/Hide
|
C21H28F3N3O2
|
1
|
| 1 |
Kd = 1.148 nM
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CP0096441
|
(4-cyclobutyl-1,4-diazepan-1-yl)((2R,4S)-4-(4-fluorophenoxy)pyrrolidin-2-yl)methanone
Show/Hide
|
C20H28FN3O2
|
1
|
| 1 |
Kd = 1.259 nM
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CP0430784
|
(4-cyclobutyl-1,4-diazepan-1-yl)(5-(4-fluorophenoxy)pyridin-3-yl)methanone
Show/Hide
|
C21H24FN3O2
|
2
|
| 1 |
Kd = 1.349 nM
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|
| 2 |
Ki = 17 nM
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CP0037773
|
(4-cyclobutyl-1,4-diazepan-1-yl)(5-(4-fluorophenoxy)pyridin-2-yl)methanone
Show/Hide
|
C21H24FN3O2
|
2
|
| 1 |
Kd = 1.413 nM
|
|
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| 2 |
Ki = 2.9 nM
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CP0158337
|
(4-cyclopentyl-1,4-diazepan-1-yl)((2R,4S)-4-(4-fluorophenoxy)pyrrolidin-2-yl)methanone
Show/Hide
|
C21H30FN3O2
|
1
|
| 1 |
Kd = 1.585 nM
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|
CP0477739
|
(4-cyclopropyl-1,4-diazepan-1-yl)(6-(4-fluorophenoxy)pyridin-3-yl)methanone
Show/Hide
|
C20H22FN3O2
|
2
|
| 1 |
Kd = 1.585 nM
|
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| 2 |
Ki = 25 nM
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|
CP0400798
|
(5-(3-chlorophenoxy)pyridin-2-yl)(4-cyclobutyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C21H24ClN3O2
|
2
|
| 1 |
Kd = 1.905 nM
|
|
|
| 2 |
Ki = 4.7 nM
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CP0095968
|
4-((3S,5R)-5-(4-cyclobutyl-1,4-diazepane-1-carbonyl)pyrrolidin-3-yloxy)benzonitrile
Show/Hide
|
C21H28N4O2
|
1
|
| 1 |
Kd = 2.089 nM
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|
CP0158336
|
(4-cyclobutyl-1,4-diazepan-1-yl)((2R,4S)-4-(3-fluorophenoxy)pyrrolidin-2-yl)methanone
Show/Hide
|
C20H28FN3O2
|
1
|
| 1 |
Kd = 2.089 nM
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CP0306436
|
(4-cyclobutyl-1,4-diazepan-1-yl)((2R,4S)-4-(4-(methylthio)phenoxy)pyrrolidin-2-yl)methanone
Show/Hide
|
C21H31N3O2S
|
1
|
| 1 |
Kd = 2.239 nM
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CP0306438
|
(4-cyclobutyl-1,4-diazepan-1-yl)((2R,4S)-4-(thiophen-3-yloxy)pyrrolidin-2-yl)methanone
Show/Hide
|
C18H27N3O2S
|
1
|
| 1 |
Kd = 2.239 nM
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CP0436819
|
(5-(4-chlorophenoxy)pyridin-2-yl)(4-cyclobutyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C21H24ClN3O2
|
2
|
| 1 |
Kd = 2.455 nM
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|
| 2 |
Ki = 5.5 nM
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|
CP0460178
|
(4-Isopropyl-piperazin-1-yl)-(5-piperidin-1-ylmethylthiophen-3-yl)-methanone
Show/Hide
|
C18H29N3OS
|
2
|
| 1 |
Kd = 2.884 nM
|
|
|
| 2 |
Ki = 3.2 nM
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|
|
CP0417988
|
3-(5-(4-cyclopropyl-1,4-diazepane-1-carbonyl)pyridin-2-yloxy)benzonitrile
Show/Hide
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C21H22N4O2
|
2
|
| 1 |
Kd = 2.951 nM
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|
| 2 |
Ki = 12 nM
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|
|
CP0446004
|
4-cyclobutyl-2-((4-(morpholinomethyl)phenoxy)methyl)morpholine
Show/Hide
|
C20H30N2O3
|
2
|
| 1 |
Kd = 3.09 nM
|
|
|
| 2 |
Ki = 18 nM
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|
|
CP0398537
|
4-[[4-(4-piperidin-1-ylbut-1-ynyl)phenyl]methyl]morpholine
Show/Hide
|
C20H28N2O
|
2
|
| 1 |
Kd = 3.236 nM
|
|
|
| 2 |
Ki = 1.738 nM
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|
|
CP0144388
|
4-(4-fluorophenyl)-2-methyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C23H30FN3O
|
2
|
| 1 |
Kd = 3.548 nM
|
|
|
| 2 |
Ki = 9 nM
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|
|
CP0320944
|
7-((1-isopropylpiperidin-4-yl)methoxy)-4-(4-methoxyphenyl)-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C24H33N3O2
|
2
|
| 1 |
Kd = 3.548 nM
|
|
|
| 2 |
Ki = 4 nM
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|
|
CP0145915
|
4-(4-chlorophenyl)-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C22H28ClN3O
|
2
|
| 1 |
Kd = 3.89 nM
|
|
|
| 2 |
Ki = 2 nM
|
|
|
|
CP0505255
|
3-(3-(piperidin-1-yl)propoxy)-5-(piperidin-1-ylmethyl)isoxazole
Show/Hide
|
C17H29N3O2
|
2
|
| 1 |
Kd = 4.898 nM
|
|
|
| 2 |
Ki = 4.1 nM
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|
|
|
CP0364802
|
4-(4-methoxyphenyl)-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C23H31N3O2
|
2
|
| 1 |
Kd = 5.888 nM
|
|
|
| 2 |
Ki = 4 nM
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|
CP0504784
|
(4-Isopropyl-piperazin-1-yl)-{5-[(2-methoxy-ethylamino)-methyl]-thiophen-2-yl}-methanone
Show/Hide
|
C16H27N3O2S
|
2
|
| 1 |
Kd = 6.918 nM
|
|
|
| 2 |
Ki = 4.4 nM
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CP0495911
|
1-(3-(2,6-dibromo-4-(piperidin-1-ylmethyl)phenoxy)propyl)piperidine
Show/Hide
|
C20H30Br2N2O
|
2
|
| 1 |
Kd = 7.244 nM
|
|
|
| 2 |
Ki = 8 nM
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|
|
CP0403088
|
(R)-4-cyclopentyl-2-((4-(morpholinomethyl)phenoxy)methyl)morpholine
Show/Hide
|
C21H32N2O3
|
2
|
| 1 |
Kd = 7.943 nM
|
|
|
| 2 |
Ki = 31 nM
|
|
|
|
CP0123274
|
(4-cyclobutyl-1,4-diazepan-1-yl)((2R,4S)-4-phenoxypyrrolidin-2-yl)methanone
Show/Hide
|
C20H29N3O2
|
1
|
| 1 |
Kd = 8.128 nM
|
|
|
|
CP0869986
|
1-[4-(2-hexahydro-1-pyridinylethoxy)benzyl]hexahydropyridine
Show/Hide
|
C19H30N2O
|
2
|
| 1 |
Kd = 8.913 nM
|
|
|
| 2 |
Ki = 8.913 nM
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|
|
|
CP0216176
|
N,N-dimethyl-3-[4-(piperidin-1-ylmethyl)phenoxy]propan-1-amine
Show/Hide
|
C17H28N2O
|
2
|
| 1 |
Kd = 9.333 nM
|
|
|
| 2 |
Ki = 3 nM
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|
|
CP0144393
|
4-(3-chlorophenyl)-2-methyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C23H30ClN3O
|
2
|
| 1 |
Kd = 9.772 nM
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|
|
| 2 |
Ki = 7 nM
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|
|
CP0895627
|
Dimethyl-[2-(4-piperidin-1-ylmethyl-phenoxy)-ethyl]-amine
Show/Hide
|
C16H26N2O
|
2
|
| 1 |
Kd = 10.47 nM
|
|
|
| 2 |
Ki = 3.89 nM
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|
CP0177530
|
4-(3,4-dichlorophenyl)-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C22H27Cl2N3O
|
2
|
| 1 |
Kd = 11.22 nM
|
|
|
| 2 |
Ki = 5 nM
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|
|
CP0144392
|
4-(4-methoxyphenyl)-2-methyl-7-(3-morpholinopropoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C23H31N3O3
|
2
|
| 1 |
Kd = 11.75 nM
|
|
|
| 2 |
Ki = 90 nM
|
|
|
|
CP0062562
|
4-((3R,5S)-5-(4-cyclobutyl-1,4-diazepane-1-carbonyl)pyrrolidin-3-yloxy)benzonitrile
Show/Hide
|
C21H28N4O2
|
1
|
| 1 |
Kd = 12.02 nM
|
|
|
|
CP0194592
|
(R)-4-(2-(2-(2-methylpyrrolidin-1-yl)ethyl)benzofuran-5-yl)benzonitrile
Show/Hide
|
C22H22N2O
|
2
|
| 1 |
Kd = 12.88 nM
|
|
|
| 2 |
Ki = 0.45 nM
|
|
|
|
CP0203168
|
3-(8-(3,4-dichlorophenyl)-5,6,7,8-tetrahydro-2,6-naphthyridin-3-yloxy)-N,N-diethylpropan-1-amine
Show/Hide
|
C21H27Cl2N3O
|
2
|
| 1 |
Kd = 14.13 nM
|
|
|
| 2 |
Ki = 7 nM
|
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|
|
CP0462298
|
4-cyclobutyl-2-((3-(morpholinomethyl)phenoxy)methyl)morpholine
Show/Hide
|
C20H30N2O3
|
2
|
| 1 |
Kd = 14.13 nM
|
|
|
| 2 |
Ki = 37 nM
|
|
|
|
CP0203172
|
4-(4-chloro-3-fluorophenyl)-2-methyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C23H29ClFN3O
|
2
|
| 1 |
Kd = 16.6 nM
|
|
|
| 2 |
Ki = 7 nM
|
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|
|
CP0501951
|
3-[4-[2-(dimethylamino)ethyl]phenoxy]-N,N-dimethylpropan-1-amine
Show/Hide
|
C15H26N2O
|
2
|
| 1 |
Kd = 16.98 nM
|
|
|
| 2 |
Ki = 6 nM
|
|
|
|
CP0145916
|
4-(3,4-dichlorophenyl)-2-methyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C23H29Cl2N3O
|
2
|
| 1 |
Kd = 18.2 nM
|
|
|
| 2 |
Ki = 18 nM
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|
|
CP0115794
|
1-((2S,4S)-2-(4-cyclobutyl-1,4-diazepane-1-carbonyl)-4-(4-(methylthio)phenoxy)pyrrolidin-1-yl)ethanone
Show/Hide
|
C23H33N3O3S
|
1
|
| 1 |
Kd = 20.89 nM
|
|
|
|
CP0082418
|
2-methyl-4-phenyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C23H31N3O
|
2
|
| 1 |
Kd = 21.38 nM
|
|
|
| 2 |
Ki = 5 nM
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|
|
|
CP0320949
|
4-(3-methoxyphenyl)-2-methyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C24H33N3O2
|
2
|
| 1 |
Kd = 25.7 nM
|
|
|
| 2 |
Ki = 8 nM
|
|
|
|
CP0399177
|
4-isopropyl-2-((3-(morpholinomethyl)phenoxy)methyl)morpholine
Show/Hide
|
C19H30N2O3
|
2
|
| 1 |
Kd = 44.67 nM
|
|
|
| 2 |
Ki = 102 nM
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|
|
CP0044460
|
N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide
Show/Hide
|
C15H24N4S
|
4
|
| 1 |
Kd = 63.1 nM
|
|
|
| 2 |
Ki = 31.62 nM
|
|
|
| 3 |
Ki = 50.12 nM
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|
|
| 4 |
Ki = 63 nM
|
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CP0203699
|
1-[[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]methyl]piperidine
Show/Hide
|
C24H32N2
|
2
|
| 1 |
Ki = 0.3388 nM
|
|
|
| 2 |
Ki = 3.388 nM
|
|
|
|
CP0218600
|
1-[[4-[4-[(1R)-1-[(2S)-2-methylpyrrolidin-1-yl]-4-phenoxybutyl]phenyl]phenyl]methyl]piperidine
Show/Hide
|
C33H42N2O
|
1
|
| 1 |
Ki = 0.5129 nM
|
|
|
|
CP0373862
|
1-[[3-(4-piperidin-1-ylbut-1-ynyl)phenyl]methyl]piperidine-4-carboxamide
Show/Hide
|
C22H31N3O
|
1
|
| 1 |
Ki = 0.5495 nM
|
|
|
|
CP0473630
|
1-[4-[4-(pyrrolidin-1-ylmethyl)phenyl]but-3-ynyl]piperidine
Show/Hide
|
C20H28N2
|
1
|
| 1 |
Ki = 0.6166 nM
|
|
|
|
CP0392161
|
1-[[4-[4-[[(2S)-2-methylpyrrolidin-1-yl]methyl]phenyl]phenyl]methyl]piperidine
Show/Hide
|
C24H32N2
|
1
|
| 1 |
Ki = 0.6607 nM
|
|
|
|
CP0501400
|
1-[[4-(4-pyrrolidin-1-ylbut-1-ynyl)phenyl]methyl]piperidine
Show/Hide
|
C20H28N2
|
1
|
| 1 |
Ki = 0.6761 nM
|
|
|
|
CP0542166
|
3-(9-(3-(piperidin-1-yl)propoxy)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinolin-6-yl)phenol
Show/Hide
|
C26H34N2O2
|
2
|
| 1 |
Ki = 0.7 nM
|
|
|
| 2 |
Ki = 5.3 nM
|
|
|
|
CP0415163
|
(4-cyclobutylpiperazin-1-yl)-[4-[(4-fluoropiperidin-1-yl)methyl]phenyl]methanone
Show/Hide
|
C21H30FN3O
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0501395
|
1-methyl-4-[[3-(4-piperidin-1-ylbut-1-ynyl)phenyl]methyl]piperazine
Show/Hide
|
C21H31N3
|
1
|
| 1 |
Ki = 0.7244 nM
|
|
|
|
CP0485428
|
1-[[4-(4-piperidin-1-ylbut-1-ynyl)phenyl]methyl]piperidine-4-carboxamide
Show/Hide
|
C22H31N3O
|
1
|
| 1 |
Ki = 0.7586 nM
|
|
|
|
CP0899329
|
Indan-1-yl-[4-(3-piperidin-1-yl-propoxy)-benzyl]-amine
Show/Hide
|
C24H32N2O
|
1
|
| 1 |
Ki = 0.8318 nM
|
|
|
|
CP0469734
|
3,5-dimethyl-1-[[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]methyl]piperidine
Show/Hide
|
C26H36N2
|
1
|
| 1 |
Ki = 0.871 nM
|
|
|
|
CP0469534
|
1-[[4-(4-piperidin-1-ylbut-1-ynyl)phenyl]methyl]-4-propan-2-ylpiperazine
Show/Hide
|
C23H35N3
|
1
|
| 1 |
Ki = 0.871 nM
|
|
|
|
CP0387972
|
1-[[4-[4-[(1S)-4-methoxy-1-[(2S)-2-methylpyrrolidin-1-yl]butyl]phenyl]phenyl]methyl]piperidine
Show/Hide
|
C28H40N2O
|
1
|
| 1 |
Ki = 0.871 nM
|
|
|
|
CP0458860
|
1-[[4-(4-piperidin-1-ylbut-1-ynyl)phenyl]methyl]piperidin-4-ol
Show/Hide
|
C21H30N2O
|
1
|
| 1 |
Ki = 0.8913 nM
|
|
|
|
CP0378613
|
6-phenyl-9-(3-(piperidin-1-yl)propoxy)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline
Show/Hide
|
C26H34N2O
|
2
|
| 1 |
Ki = 0.9 nM
|
|
|
| 2 |
Ki = 4 nM
|
|
|
|
CP0276306
|
(4-isopropyl-1,4-diazepan-1-yl)(1-methyl-3-(morpholinomethyl)-1H-indol-6-yl)methanone
Show/Hide
|
C23H34N4O2
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0514497
|
N,N-dimethyl-1-[4-(4-piperidin-1-ylbut-1-ynyl)phenyl]methanamine
Show/Hide
|
C18H26N2
|
1
|
| 1 |
Ki = 0.912 nM
|
|
|
|
CP0897042
|
Dimethyl-[4-(3-piperidin-1-yl-propoxy)-benzyl]-amine
Show/Hide
|
C17H28N2O
|
1
|
| 1 |
Ki = 0.9333 nM
|
|
|
|
CP0855338
|
1-[4-(3-Piperidin-1-yl-propoxy)-benzyl]-piperidine-4-carboxylic acid amide
Show/Hide
|
C21H33N3O2
|
1
|
| 1 |
Ki = 0.955 nM
|
|
|
|
CP0496939
|
1-methyl-4-[[4-(4-piperidin-1-ylbut-1-ynyl)phenyl]methyl]piperazine
Show/Hide
|
C21H31N3
|
1
|
| 1 |
Ki = 0.9772 nM
|
|
|
|
CP0413311
|
[4-(azepan-1-ylmethyl)phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone
Show/Hide
|
C21H33N3O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0525656
|
(4-propan-2-ylpiperazin-1-yl)-[4-(pyrrolidin-1-ylmethyl)phenyl]methanone
Show/Hide
|
C19H29N3O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0439211
|
N-ethyl-N-[[4-(4-piperidin-1-ylbut-1-ynyl)phenyl]methyl]ethanamine
Show/Hide
|
C20H30N2
|
1
|
| 1 |
Ki = 1.096 nM
|
|
|
|
CP0304085
|
1-[2-[4-[4-(2-piperidin-1-ylethyl)phenyl]phenyl]ethyl]piperidine
Show/Hide
|
C26H36N2
|
1
|
| 1 |
Ki = 1.175 nM
|
|
|
|
CP0464174
|
4-(9-(3-(piperidin-1-yl)propoxy)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinolin-6-yl)benzonitrile
Show/Hide
|
C27H33N3O
|
2
|
| 1 |
Ki = 1.2 nM
|
|
|
| 2 |
Ki = 59 nM
|
|
|
|
CP0464175
|
6-(3-chlorophenyl)-9-(3-(piperidin-1-yl)propoxy)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline
Show/Hide
|
C26H33ClN2O
|
2
|
| 1 |
Ki = 1.2 nM
|
|
|
| 2 |
Ki = 4.7 nM
|
|
|
|
CP0137854
|
1-(4-Chloro-phenyl)-4-(4-cyclopentyl-piperazin-1-yl)-butane-1,4-dione; hydrochloride
Show/Hide
|
C19H25ClN2O2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0897014
|
Diethyl-[3-(4-piperidin-1-ylmethyl-phenoxy)-propyl]-amine
Show/Hide
|
C19H32N2O
|
1
|
| 1 |
Ki = 1.23 nM
|
|
|
|
CP0428625
|
1-[[4-[4-[(1S)-1-[(2S)-2-methylpyrrolidin-1-yl]pentyl]phenyl]phenyl]methyl]piperidine
Show/Hide
|
C28H40N2
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0495982
|
1-[[4-[4-[(1R)-4-(4-methoxyphenoxy)-1-[(2S)-2-methylpyrrolidin-1-yl]butyl]phenyl]phenyl]methyl]piperidine
Show/Hide
|
C34H44N2O2
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0428627
|
1-[1-[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]pentyl]piperidine
Show/Hide
|
C28H40N2
|
1
|
| 1 |
Ki = 1.288 nM
|
|
|
|
CP0535356
|
6-(2-methoxyphenyl)-9-(3-(piperidin-1-yl)propoxy)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline
Show/Hide
|
C27H36N2O2
|
2
|
| 1 |
Ki = 1.3 nM
|
|
|
| 2 |
Ki = 33.5 nM
|
|
|
|
CP0535357
|
6-(4-nitrophenyl)-9-(3-(piperidin-1-yl)propoxy)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline
Show/Hide
|
C26H33N3O3
|
2
|
| 1 |
Ki = 1.3 nM
|
|
|
| 2 |
Ki = 6.8 nM
|
|
|
|
CP0058367
|
(4-cyclobutylpiperazin-1-yl)-[4-(morpholin-4-ylmethyl)phenyl]methanone
Show/Hide
|
C20H29N3O2
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0885915
|
1-Methyl-4-[4-(3-piperidin-1-yl-propoxy)-benzyl]-piperazine
Show/Hide
|
C20H33N3O
|
1
|
| 1 |
Ki = 1.349 nM
|
|
|
|
CP0439214
|
N,N-diethyl-4-[4-(piperidin-1-ylmethyl)phenyl]but-3-yn-1-amine
Show/Hide
|
C20H30N2
|
1
|
| 1 |
Ki = 1.349 nM
|
|
|
|
CP0346171
|
(4-cyclobutylpiperazin-1-yl)(3-(morpholinomethyl)-1H-indol-6-yl)methanone
Show/Hide
|
C22H30N4O2
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0392162
|
1-[[4-[4-[[(2R)-2-methylpyrrolidin-1-yl]methyl]phenyl]phenyl]methyl]piperidine
Show/Hide
|
C24H32N2
|
1
|
| 1 |
Ki = 1.479 nM
|
|
|
|
CP0447861
|
[4-[(4-fluoropiperidin-1-yl)methyl]phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone
Show/Hide
|
C20H30FN3O
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0900297
|
4-Benzyl-1-[4-(3-piperidin-1-yl-propoxy)-benzyl]-piperidine
Show/Hide
|
C27H38N2O
|
1
|
| 1 |
Ki = 1.514 nM
|
|
|
|
CP0387966
|
1-[[4-[4-[(1R)-1-[(2S)-2-methylpyrrolidin-1-yl]pentyl]phenyl]phenyl]methyl]piperidine
Show/Hide
|
C28H40N2
|
1
|
| 1 |
Ki = 1.549 nM
|
|
|
|
CP0522315
|
N,N-dimethyl-4-[9-(3-piperidin-1-ylpropoxy)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinolin-6-yl]aniline
Show/Hide
|
C28H39N3O
|
2
|
| 1 |
Ki = 1.6 nM
|
|
|
| 2 |
Ki = 5.3 nM
|
|
|
|
CP0302876
|
(4-cyclobutylpiperazin-1-yl)(3-(piperidin-1-ylmethyl)-1H-indol-7-yl)methanone
Show/Hide
|
C23H32N4O
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0085944
|
2-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]-3,4-dihydro-1H-isoquinoline
Show/Hide
|
C24H32N2O
|
1
|
| 1 |
Ki = 1.698 nM
|
|
|
|
CP0449470
|
N-[[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]methyl]cyclohexanamine
Show/Hide
|
C25H34N2
|
1
|
| 1 |
Ki = 1.698 nM
|
|
|
|
CP0378617
|
4-(9-(3-(piperidin-1-yl)propoxy)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinolin-6-yl)phenol
Show/Hide
|
C26H34N2O2
|
2
|
| 1 |
Ki = 1.7 nM
|
|
|
| 2 |
Ki = 68.7 nM
|
|
|
|
CP0444721
|
6-(4-fluorophenyl)-9-(3-(piperidin-1-yl)propoxy)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline
Show/Hide
|
C26H33FN2O
|
2
|
| 1 |
Ki = 1.7 nM
|
|
|
| 2 |
Ki = 4.3 nM
|
|
|
|
CP0495753
|
6-(3-methoxyphenyl)-9-(3-(piperidin-1-yl)propoxy)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline
Show/Hide
|
C27H36N2O2
|
2
|
| 1 |
Ki = 1.7 nM
|
|
|
| 2 |
Ki = 7.5 nM
|
|
|
|
CP0476375
|
N-[[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]methyl]-N-propylpropan-1-amine
Show/Hide
|
C25H36N2
|
1
|
| 1 |
Ki = 1.738 nM
|
|
|
|
CP0373002
|
1-[4-[4-[(dimethylamino)methyl]phenyl]phenyl]-N,N-dimethylmethanamine
Show/Hide
|
C18H24N2
|
1
|
| 1 |
Ki = 1.862 nM
|
|
|
|
CP0088873
|
(4-isopropylpiperazin-1-yl)(1-(methylsulfonyl)-3-(piperidin-1-ylmethyl)-1H-indol-6-yl)methanone
Show/Hide
|
C23H34N4O3S
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0438700
|
1-benzyl-4-[[4-(4-piperidin-1-ylbut-1-ynyl)phenyl]methyl]piperazine
Show/Hide
|
C27H35N3
|
1
|
| 1 |
Ki = 1.905 nM
|
|
|
|
CP0386069
|
N-ethyl-N-[[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]methyl]ethanamine
Show/Hide
|
C23H32N2
|
1
|
| 1 |
Ki = 1.95 nM
|
|
|
|
CP0304086
|
1-[[4-[4-(2-piperidin-1-ylethyl)phenyl]phenyl]methyl]piperidine
Show/Hide
|
C25H34N2
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0427547
|
1-[[4-[4-[(1R)-4-methoxy-1-[(2S)-2-methylpyrrolidin-1-yl]butyl]phenyl]phenyl]methyl]piperidine
Show/Hide
|
C28H40N2O
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0434101
|
6-(3-ethynylphenyl)-9-(3-(piperidin-1-yl)propoxy)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline
Show/Hide
|
C28H34N2O
|
2
|
| 1 |
Ki = 2 nM
|
|
|
| 2 |
Ki = 14.3 nM
|
|
|
|
CP0489278
|
9-(3-(piperidin-1-yl)propoxy)-6-(3-(trifluoromethyl)phenyl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline
Show/Hide
|
C27H33F3N2O
|
2
|
| 1 |
Ki = 2 nM
|
|
|
| 2 |
Ki = 24 nM
|
|
|
|
CP0522379
|
9-(3-(piperidin-1-yl)propoxy)-6-p-tolyl-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline
Show/Hide
|
C27H36N2O
|
2
|
| 1 |
Ki = 2 nM
|
|
|
| 2 |
Ki = 4.7 nM
|
|
|
|
CP0342769
|
(4-cyclopropylpiperazin-1-yl)(3-(morpholinomethyl)-1H-indol-6-yl)methanone
Show/Hide
|
C21H28N4O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0431718
|
(4-cyclopropylpiperazin-1-yl)-[4-[(4-fluoropiperidin-1-yl)methyl]phenyl]methanone
Show/Hide
|
C20H28FN3O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0387969
|
1-[[4-[4-[(1S)-4-(4-methoxyphenoxy)-1-[(2S)-2-methylpyrrolidin-1-yl]butyl]phenyl]phenyl]methyl]piperidine
Show/Hide
|
C34H44N2O2
|
1
|
| 1 |
Ki = 2.042 nM
|
|
|
|
CP0302875
|
(4-isopropylpiperazin-1-yl)(3-(morpholinomethyl)-1H-indol-6-yl)methanone
Show/Hide
|
C21H30N4O2
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0469740
|
N,N-dimethyl-1-[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]methanamine
Show/Hide
|
C21H28N2
|
1
|
| 1 |
Ki = 2.188 nM
|
|
|
|
CP0428002
|
6-(4-chlorophenyl)-9-(3-(piperidin-1-yl)propoxy)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline
Show/Hide
|
C26H33ClN2O
|
2
|
| 1 |
Ki = 2.2 nM
|
|
|
| 2 |
Ki = 7.3 nM
|
|
|
|
CP0940705
|
4-[3-(4-Piperidin-1-ylmethyl-phenoxy)-propyl]-morpholine
Show/Hide
|
C19H30N2O2
|
1
|
| 1 |
Ki = 2.291 nM
|
|
|
|
CP0524280
|
6-(2-chlorophenyl)-9-(3-(piperidin-1-yl)propoxy)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline
Show/Hide
|
C26H33ClN2O
|
2
|
| 1 |
Ki = 2.3 nM
|
|
|
| 2 |
Ki = 10.7 nM
|
|
|
|
CP0395478
|
1-[[4-[4-[(1S)-1-[(2R)-2-methylpyrrolidin-1-yl]pentyl]phenyl]phenyl]methyl]piperidine
Show/Hide
|
C28H40N2
|
1
|
| 1 |
Ki = 2.344 nM
|
|
|
|
CP0373004
|
4-methyl-1-[[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]methyl]piperidine
Show/Hide
|
C25H34N2
|
1
|
| 1 |
Ki = 2.399 nM
|
|
|
|
CP0427549
|
(2S)-2-methyl-1-[(1S)-1-[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]pentyl]piperidine
Show/Hide
|
C29H42N2
|
1
|
| 1 |
Ki = 2.455 nM
|
|
|
|
CP0476273
|
1-[[4-[4-[(1R)-1-[(2R)-2-methylpyrrolidin-1-yl]pentyl]phenyl]phenyl]methyl]piperidine
Show/Hide
|
C28H40N2
|
1
|
| 1 |
Ki = 2.455 nM
|
|
|
|
CP0378616
|
6-(4-(methylthio)phenyl)-9-(3-(piperidin-1-yl)propoxy)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline
Show/Hide
|
C27H36N2OS
|
2
|
| 1 |
Ki = 2.5 nM
|
|
|
| 2 |
Ki = 5.2 nM
|
|
|
|
CP0056218
|
(Z)-but-2-enedioic acid;[4-(morpholin-4-ylmethyl)phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone
Show/Hide
|
C19H29N3O2
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0902071
|
2-[3-(Imidazol-4-yl)-propyl]-1-(4-bromo-benzyl)-isothiourea dihydrobromide
Show/Hide
|
C14H18Br2N4S
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0041493
|
Clobenpropit
Show/Hide
|
C14H17ClN4S
|
2
|
| 1 |
Ki = 2.512 nM
|
|
|
| 2 |
Ki = 3.162 nM
|
|
|
|
CP0476272
|
1-[[4-[4-[(1S)-1-[(2S)-2-methylpyrrolidin-1-yl]-4-phenoxybutyl]phenyl]phenyl]methyl]piperidine
Show/Hide
|
C33H42N2O
|
1
|
| 1 |
Ki = 2.57 nM
|
|
|
|
CP0119048
|
1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine
Show/Hide
|
C17H26ClNO
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0386068
|
N-methyl-N-[[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]methyl]cyclohexanamine
Show/Hide
|
C26H36N2
|
1
|
| 1 |
Ki = 2.754 nM
|
|
|
|
CP0302874
|
(4-isopropylpiperazin-1-yl)(3-(piperidin-1-ylmethyl)-1H-indol-6-yl)methanone
Show/Hide
|
C22H32N4O
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0401359
|
N-[[4-[4-(diethylaminomethyl)phenyl]phenyl]methyl]-N-ethylethanamine
Show/Hide
|
C22H32N2
|
1
|
| 1 |
Ki = 2.818 nM
|
|
|
|
CP0428463
|
(2S)-2-methyl-1-[(1R)-1-[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]pentyl]piperidine
Show/Hide
|
C29H42N2
|
1
|
| 1 |
Ki = 3.02 nM
|
|
|
|
CP0847507
|
2-[3-(Imidazol-4-yl)-propyl]-1-(4-iodo-benzyl)-isothiourea dihydrobromide
Show/Hide
|
C14H19Br2IN4S
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0373864
|
4-benzyl-1-[[4-(4-piperidin-1-ylbut-1-ynyl)phenyl]methyl]piperidine
Show/Hide
|
C28H36N2
|
1
|
| 1 |
Ki = 3.467 nM
|
|
|
|
CP0485189
|
2-(9-(3-(piperidin-1-yl)propoxy)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinolin-6-yl)phenol
Show/Hide
|
C26H34N2O2
|
2
|
| 1 |
Ki = 3.7 nM
|
|
|
| 2 |
Ki = 150 nM
|
|
|
|
CP0477742
|
(4-cyclobutyl-1,4-diazepan-1-yl)(5-(phenylthio)pyridin-2-yl)methanone
Show/Hide
|
C21H25N3OS
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0439213
|
4-[4-[4-(piperidin-1-ylmethyl)phenyl]but-3-ynyl]thiomorpholine
Show/Hide
|
C20H28N2S
|
1
|
| 1 |
Ki = 3.802 nM
|
|
|
|
CP0469737
|
N-[[4-[4-(2-piperidin-1-ylethyl)phenyl]phenyl]methyl]-N-propylpropan-1-amine
Show/Hide
|
C26H38N2
|
1
|
| 1 |
Ki = 3.89 nM
|
|
|
|
CP0854868
|
cyclopentyl-[5-(1H-imidazol-4-yl)-pentyl]-amine
Show/Hide
|
C13H23N3
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0371920
|
9-(3-(piperidin-1-yl)propoxy)-6-(4-(trifluoromethoxy)phenyl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline
Show/Hide
|
C27H33F3N2O2
|
2
|
| 1 |
Ki = 4 nM
|
|
|
| 2 |
Ki = 8.7 nM
|
|
|
|
CP0464176
|
6-(4-ethynylphenyl)-9-(3-(piperidin-1-yl)propoxy)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline
Show/Hide
|
C28H34N2O
|
2
|
| 1 |
Ki = 4 nM
|
|
|
| 2 |
Ki = 15.7 nM
|
|
|
|
CP0532840
|
1-(9-piperidin-1-ylnonyl)piperidine
Show/Hide
|
C19H38N2
|
1
|
| 1 |
Ki = 4.467 nM
|
|
|
|
CP0477740
|
(4-cyclobutyl-1,4-diazepan-1-yl)(5-(4-fluorophenylthio)pyridin-2-yl)methanone
Show/Hide
|
C21H24FN3OS
|
1
|
| 1 |
Ki = 4.6 nM
|
|
|
|
CP0427895
|
9-(3-(piperidin-1-yl)propoxy)-6-(4-(trifluoromethyl)phenyl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline
Show/Hide
|
C27H33F3N2O
|
2
|
| 1 |
Ki = 4.7 nM
|
|
|
| 2 |
Ki = 40.3 nM
|
|
|
|
CP0342771
|
(4-cyclobutylpiperazin-1-yl)(3-(morpholinomethyl)-1H-indol-7-yl)methanone
Show/Hide
|
C22H30N4O2
|
1
|
| 1 |
Ki = 4.9 nM
|
|
|
|
CP0538253
|
[4-[(dimethylamino)methyl]phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone
Show/Hide
|
C17H27N3O
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0875065
|
2-[3-(Imidazol-4-yl)-propyl]-1-(4-fluoro-benzyl)-isothiourea dihydrobromide
Show/Hide
|
C14H19Br2FN4S
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0439212
|
4-[4-[4-(piperidin-1-ylmethyl)phenyl]but-3-ynyl]morpholine
Show/Hide
|
C20H28N2O
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0387898
|
2-[4-[4-[2-(dimethylamino)ethyl]phenyl]phenyl]-N,N-dimethylethanamine
Show/Hide
|
C20H28N2
|
1
|
| 1 |
Ki = 5.129 nM
|
|
|
|
CP0439198
|
1-methyl-4-[4-[4-(piperidin-1-ylmethyl)phenyl]but-3-ynyl]piperazine
Show/Hide
|
C21H31N3
|
1
|
| 1 |
Ki = 5.248 nM
|
|
|
|
CP0046186
|
(4-cyclopropylpiperazin-1-yl)-[4-(morpholin-4-ylmethyl)phenyl]methanone;hydrochloride
Show/Hide
|
C19H27N3O2
|
1
|
| 1 |
Ki = 5.4 nM
|
|
|
|
CP0438771
|
(4-cyclobutyl-1,4-diazepan-1-yl)(5-(3-fluorophenoxy)pyridin-2-yl)methanone
Show/Hide
|
C21H24FN3O2
|
1
|
| 1 |
Ki = 5.5 nM
|
|
|
|
CP0428596
|
1-[1-[4-[4-[[(2R)-2-methylpyrrolidin-1-yl]methyl]phenyl]phenyl]-2-phenylethyl]piperidine
Show/Hide
|
C31H38N2
|
1
|
| 1 |
Ki = 5.623 nM
|
|
|
|
CP0533338
|
(4-cyclobutyl-1,4-diazepan-1-yl)(4-(4-fluorophenoxy)pyridin-2-yl)methanone
Show/Hide
|
C21H24FN3O2
|
1
|
| 1 |
Ki = 5.7 nM
|
|
|
|
CP0530483
|
(4-Isopropyl-piperazin-1-yl)-(6-piperidin-1-ylmethylpyridin-3-yl)-methanethione
Show/Hide
|
C19H30N4S
|
1
|
| 1 |
Ki = 5.8 nM
|
|
|
|
CP0538252
|
[4-(diethylaminomethyl)phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone
Show/Hide
|
C19H31N3O
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0373003
|
4-methyl-1-[[4-[4-[(4-methylpiperidin-1-yl)methyl]phenyl]phenyl]methyl]piperidine
Show/Hide
|
C26H36N2
|
1
|
| 1 |
Ki = 6.166 nM
|
|
|
|
CP0372842
|
1-[4-[[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]methyl]piperazin-1-yl]ethanone
Show/Hide
|
C25H33N3O
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0852004
|
2-[3-(Imidazol-4-yl)-propyl]-1-(3,4-dichloro-benzyl)-isothiourea dihydrobromide
Show/Hide
|
C14H18Br2Cl2N4S
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0913221
|
2-[3-(Imidazol-4-yl)-propyl]-1-(4-methyl-benzyl)-isothiourea dihydrobromide
Show/Hide
|
C15H22Br2N4S
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0469736
|
N-methyl-1-phenyl-N-[[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]methyl]methanamine
Show/Hide
|
C27H32N2
|
1
|
| 1 |
Ki = 6.761 nM
|
|
|
|
CP0478514
|
4-[5-(3-Piperidin-1-yl-propoxy)-pyridin-2-ylmethyl]-morpholine
Show/Hide
|
C18H29N3O2
|
1
|
| 1 |
Ki = 6.9 nM
|
|
|
|
CP0881055
|
ethyl-[5-(1H-imidazol-4-yl)-pentyl]-amine
Show/Hide
|
C10H19N3
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0439526
|
3-(1H-imidazol-5-yl)propyl N'-[2-(4-bromophenyl)ethyl]carbamimidothioate
Show/Hide
|
C15H19BrN4S
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0857594
|
2-[3-(Imidazol-4-yl)-propyl]-1-(4-methoxy-benzyl)-isothiourea dihydrobromide
Show/Hide
|
C15H22Br2N4OS
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0857599
|
2-[3-(Imidazol-4-yl)-propyl]-1-(2-chloro-benzyl)-isothiourea dihydrobromide
Show/Hide
|
C14H19Br2ClN4S
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0875064
|
2-[3-(Imidazol-4-yl)-propyl]-1-(benzyl)-isothioureadihydrobromide
Show/Hide
|
C14H20Br2N4S
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0879917
|
2-[3-(Imidazol-4-yl)-propyl]-1-(3-chloro-benzyl)-isothiourea dihydrobromide
Show/Hide
|
C14H19Br2ClN4S
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0902072
|
IODOPHENPROPIT
Show/Hide
|
C15H21Br2IN4S
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0940702
|
Phenyl-[4-(3-piperidin-1-yl-propoxy)-benzyl]-amine
Show/Hide
|
C21H28N2O
|
1
|
| 1 |
Ki = 8.318 nM
|
|
|
|
CP0373000
|
2-[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]-N,N-dipropylacetamide
Show/Hide
|
C26H36N2O
|
1
|
| 1 |
Ki = 8.511 nM
|
|
|
|
CP0386066
|
N-[[4-[4-[(dipropylamino)methyl]phenyl]phenyl]methyl]-N-propylpropan-1-amine
Show/Hide
|
C26H40N2
|
1
|
| 1 |
Ki = 9.333 nM
|
|
|
|
CP0870385
|
2-[3-(Imidazol-4-yl)-propyl]-1-[2-(4-chloro-phenyl)-ethyl]-isothiourea dihydrobromide
Show/Hide
|
C15H21Br2ClN4S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0879916
|
2-[3-(Imidazol-4-yl)-propyl]-1-[3-(phenyl)-propyl]-isothiourea dihydrobromide
Show/Hide
|
C16H24Br2N4S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0477745
|
(4-cyclopropyl-1,4-diazepan-1-yl)(6-phenoxypyridin-3-yl)methanone
Show/Hide
|
C20H23N3O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0514576
|
(4-cyclopropyl-1,4-diazepan-1-yl)(5-(3,4-dichlorophenoxy)pyridin-2-yl)methanone
Show/Hide
|
C20H21Cl2N3O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0823737
|
SID50106398
Show/Hide
|
C5H11Cl2N3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0514507
|
(4-cyclobutyl-1,4-diazepan-1-yl)(5-phenoxypyridin-3-yl)methanone
Show/Hide
|
C21H25N3O2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0144402
|
4-(4-methoxyphenyl)-2-methyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C24H33N3O2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0359353
|
(4-isopropylpiperazin-1-yl)(3-(morpholinomethyl)-1H-indol-7-yl)methanone
Show/Hide
|
C21H30N4O2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0475915
|
(4-Isopropyl-piperazin-1-yl)-(5-piperidin-1-ylmethylthiophen-2-yl)-methanone
Show/Hide
|
C18H29N3OS
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0469733
|
4-[[4-[4-(morpholin-4-ylmethyl)phenyl]phenyl]methyl]morpholine
Show/Hide
|
C22H28N2O2
|
1
|
| 1 |
Ki = 12.3 nM
|
|
|
|
CP0870389
|
2-[3-(Imidazol-4-yl)-propyl]-1-[2-(4-methyl-phenyl)-ethyl]-isothiourea dihydrobromide
Show/Hide
|
C16H24Br2N4S
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0082412
|
4-(3,4-dichlorophenyl)-7-((1-isopropylpiperidin-4-yl)methoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C23H29Cl2N3O
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0144389
|
7-((1-isopropylpiperidin-4-yl)methoxy)-4-(4-methoxyphenyl)-2-methyl-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C25H35N3O2
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0157752
|
4-(3,4-dichlorophenyl)-7-((1-isopropylpiperidin-4-yl)methoxy)-2-methyl-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C24H31Cl2N3O
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0177532
|
7-(3-morpholinopropoxy)-4-phenyl-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C21H27N3O2
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0320946
|
N,N-diethyl-3-[[8-(4-methoxyphenyl)-6-methyl-7,8-dihydro-5H-2,6-naphthyridin-3-yl]oxy]propan-1-amine
Show/Hide
|
C23H33N3O2
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0477744
|
(6-(4-chlorophenoxy)pyridin-3-yl)(4-cyclopropyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C20H22ClN3O2
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0944560
|
1-Methyl-4-[3-(4-piperidin-1-ylmethyl-phenoxy)-propyl]-piperazine
Show/Hide
|
C20H33N3O
|
1
|
| 1 |
Ki = 13.49 nM
|
|
|
|
CP0542993
|
N,N-dimethyl-2-[4-(2-piperidin-1-ylethoxy)phenyl]ethanamine
Show/Hide
|
C17H28N2O
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0501399
|
4-[4-[3-(piperidin-1-ylmethyl)phenyl]but-3-ynyl]morpholine
Show/Hide
|
C20H28N2O
|
1
|
| 1 |
Ki = 14.45 nM
|
|
|
|
CP0177531
|
4-(4-chlorophenyl)-2-methyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C23H30ClN3O
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0324701
|
(4-isopropylpiperazin-1-yl)(1-methyl-3-(morpholinomethyl)-1H-indol-6-yl)methanone
Show/Hide
|
C22H32N4O2
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0342772
|
(4-cyclobutylpiperazin-1-yl)(3-(piperidin-1-ylmethyl)benzo[b]thiophen-5-yl)methanone
Show/Hide
|
C23H31N3OS
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0522005
|
(4-Isopropyl-piperazin-1-yl)-(6-morpholin-4-ylmethylpyridin-3-yl)-methanone
Show/Hide
|
C18H28N4O2
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0862308
|
4-chloro-benzyl-[4-(1H-imidazol-4-yl)-butyl]-amine
Show/Hide
|
C14H18ClN3
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0144396
|
3-(8-(3,4-dichlorophenyl)-6-methyl-5,6,7,8-tetrahydro-2,6-naphthyridin-3-yloxy)-N,N-diethylpropan-1-amine
Show/Hide
|
C22H29Cl2N3O
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0514096
|
(4-cyclopropyl-1,4-diazepan-1-yl)(6-(3-fluorophenoxy)pyridin-3-yl)methanone
Show/Hide
|
C20H22FN3O2
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0476376
|
4-methyl-1-[2-[4-[4-[2-(4-methylpiperidin-1-yl)ethyl]phenyl]phenyl]ethyl]piperidine
Show/Hide
|
C28H40N2
|
1
|
| 1 |
Ki = 16.6 nM
|
|
|
|
CP0432707
|
N,N-dimethyl-2-phenyl-1-[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]ethanamine
Show/Hide
|
C28H34N2
|
1
|
| 1 |
Ki = 16.6 nM
|
|
|
|
CP0388687
|
(6-(2-chlorophenoxy)pyridin-3-yl)(4-cyclobutyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C21H24ClN3O2
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0506136
|
(6-(3-chlorophenoxy)pyridin-3-yl)(4-cyclopropyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C20H22ClN3O2
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0514260
|
3-(4-((dimethylamino)methyl)phenoxy)-N,N-dimethylpropan-1-amine
Show/Hide
|
C14H24N2O
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0430782
|
(6-(3,4-dichlorophenoxy)pyridin-3-yl)(4-isopropyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C20H23Cl2N3O2
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0428622
|
1-[[4-[4-(2-phenyl-1-piperidin-1-ylethyl)phenyl]phenyl]methyl]piperidine
Show/Hide
|
C31H38N2
|
1
|
| 1 |
Ki = 19.05 nM
|
|
|
|
CP0469735
|
4-[[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]methyl]morpholine
Show/Hide
|
C23H30N2O
|
1
|
| 1 |
Ki = 19.5 nM
|
|
|
|
CP0377713
|
3-(1H-imidazol-5-yl)propyl N'-(4-phenylbutyl)carbamimidothioate
Show/Hide
|
C17H24N4S
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0870384
|
2-[3-(Imidazol-4-yl)-propyl]-1-[2-(phenyl)-ethyl]-isothiourea dihydrobromide
Show/Hide
|
C15H22Br2N4S
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0902073
|
2-[3-(Imidazol-4-yl)-propyl]-1-[2-(4-methoxy-phenyl)-ethyl]-isothiourea dihydrobromide
Show/Hide
|
C16H24Br2N4OS
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0433629
|
(4-methylpiperazin-1-yl)-[4-(morpholin-4-ylmethyl)phenyl]methanone
Show/Hide
|
C17H25N3O2
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0144385
|
N,N-diethyl-3-[[8-(4-methoxyphenyl)-5,6,7,8-tetrahydro-2,6-naphthyridin-3-yl]oxy]propan-1-amine
Show/Hide
|
C22H31N3O2
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0037479
|
(4-cyclopropylpiperazin-1-yl)(4-(3,4-dichlorophenoxy)-3-((methylamino)methyl)phenyl)methanone
Show/Hide
|
C22H25Cl2N3O2
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0478513
|
(4-Isopropyl-piperazin-1-yl)-(5-morpholin-4-ylmethylpyrazin-2-yl)-methanone
Show/Hide
|
C17H27N5O2
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0129069
|
4-cyclopentyl-6-piperazin-1-ylpyrimidin-2-amine
Show/Hide
|
C13H21N5
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0538254
|
(4-methylpiperazin-1-yl)-[4-(piperidin-1-ylmethyl)phenyl]methanone
Show/Hide
|
C18H27N3O
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0512560
|
(4-Isopropyl-piperazin-1-yl)-(5-morpholin-4-ylmethylthiophen-2-yl)-methanone
Show/Hide
|
C17H27N3O2S
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0346170
|
(4-isopropylpiperazin-1-yl)(3-(piperidin-1-ylmethyl)-1H-indol-7-yl)methanone
Show/Hide
|
C22H32N4O
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0432836
|
Aplysamine-1
Show/Hide
|
C15H24Br2N2O
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0400801
|
(6-(2-chlorophenoxy)pyridin-3-yl)(4-isopropylpiperazin-1-yl)methanone
Show/Hide
|
C19H22ClN3O2
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0881053
|
cyclohexyl-[4-(1H-imidazol-4-yl)-butyl]-amine tartaric acid
Show/Hide
|
C13H23N3
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0858273
|
2-[3-(Imidazol-4-yl)-propyl]-1-(3,3-diphenylpropyl)-isothiourea dihydrobromide
Show/Hide
|
C22H28Br2N4S
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0478511
|
(4-Isopropyl-yl)-(1-methyl-4-piperidin-1-ylmethyl-1Hpyrrol-2-yl)-methanone
Show/Hide
|
C19H32N4O
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0400800
|
(4-ethyl-1,4-diazepan-1-yl)(6-(4-fluorophenoxy)pyridin-3-yl)methanone
Show/Hide
|
C19H22FN3O2
|
1
|
| 1 |
Ki = 34 nM
|
|
|
|
CP0522003
|
(4-Isopropyl-piperazin-1-yl)-{5-[(2-methoxy-ethylamino)-methyl]-furan-2-yl}-methanone
Show/Hide
|
C16H27N3O3
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0424984
|
3-(2,6-dibromo-4-((dimethylamino)methyl)phenoxy)-N,N-dimethylpropan-1-amine
Show/Hide
|
C14H22Br2N2O
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0505254
|
(4-Isopropyl-piperazin-1-yl)-(5-morpholin-4-ylmethylthiophen-3-yl)-methanone
Show/Hide
|
C17H27N3O2S
|
1
|
| 1 |
Ki = 37 nM
|
|
|
|
CP0381645
|
N-[[4-[4-[[cyclohexyl(methyl)amino]methyl]phenyl]phenyl]methyl]-N-methylcyclohexanamine
Show/Hide
|
C28H40N2
|
1
|
| 1 |
Ki = 37.15 nM
|
|
|
|
CP0849120
|
cycloheptyl-[4-(1H-imidazol-4-yl)-butyl]-amine
Show/Hide
|
C14H25N3
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0854867
|
cyclopentyl-[4-(1H-imidazol-4-yl)-butyl]-amine
Show/Hide
|
C12H21N3
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0875455
|
tert-butyl-[5-(1H-imidazol-4-yl)-pentyl]-amine
Show/Hide
|
C12H23N3
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0495912
|
2-(4-(2-(dimethylamino)ethoxy)phenyl)-N,N-dimethylethanamine
Show/Hide
|
C14H24N2O
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0522685
|
(6-(2-chlorophenoxy)pyridin-3-yl)(4-cyclopentylpiperazin-1-yl)methanone
Show/Hide
|
C21H24ClN3O2
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0514582
|
(4-cyclobutyl-1,4-diazepan-1-yl)(4-phenoxypyridin-2-yl)methanone
Show/Hide
|
C21H25N3O2
|
1
|
| 1 |
Ki = 41 nM
|
|
|
|
CP0203170
|
4-(4-methoxyphenyl)-7-(3-morpholinopropoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
Show/Hide
|
C22H29N3O3
|
1
|
| 1 |
Ki = 43 nM
|
|
|
|
CP0240512
|
(3-((4-cyclobutylpiperazin-1-yl)methyl)-1H-indol-6-yl)(morpholino)methanone
Show/Hide
|
C22H30N4O2
|
1
|
| 1 |
Ki = 43 nM
|
|
|
|
CP0511764
|
1-[[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]methyl]piperidin-2-one
Show/Hide
|
C24H30N2O
|
1
|
| 1 |
Ki = 46.77 nM
|
|
|
|
CP0399176
|
4-isopropyl-2-((4-(morpholinomethyl)phenoxy)methyl)morpholine
Show/Hide
|
C19H30N2O3
|
1
|
| 1 |
Ki = 49 nM
|
|
|
|
CP0346172
|
(4-isopropylpiperazin-1-yl)(3-(piperidin-1-ylmethyl)benzo[b]thiophen-5-yl)methanone
Show/Hide
|
C22H31N3OS
|
1
|
| 1 |
Ki = 50 nM
|
|
|
|
CP0878596
|
Diethyl-[2-(4-piperidin-1-ylmethyl-phenoxy)-ethyl]-amine
Show/Hide
|
C18H30N2O
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0957242
|
1-[3-(4-Cyclohexylmethyl-phenoxy)-propyl]-piperidine
Show/Hide
|
C21H33NO
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0530481
|
(4-Isopropyl-piperazin-1-yl)-(5-morpholin-4-ylmethylfuran-2-yl)-methanone
Show/Hide
|
C17H27N3O3
|
1
|
| 1 |
Ki = 54 nM
|
|
|
|
CP0498417
|
1-(4-phenylbut-3-ynyl)piperidine
Show/Hide
|
C15H19N
|
1
|
| 1 |
Ki = 56.23 nM
|
|
|
|
CP0877509
|
[5-(1H-imidazol-4-yl)-pentyl]-diethyl-amine
Show/Hide
|
C12H23N3
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0400802
|
(6-(4-chlorophenoxy)pyridin-3-yl)(4-isopropylpiperazin-1-yl)methanone
Show/Hide
|
C19H22ClN3O2
|
1
|
| 1 |
Ki = 73 nM
|
|
|
|
CP0372999
|
4-[[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]methoxy]benzonitrile
Show/Hide
|
C26H26N2O
|
1
|
| 1 |
Ki = 75.86 nM
|
|
|
|
CP0417142
|
(6-(3,4-dichlorophenoxy)pyridin-3-yl)(4-isopropylpiperazin-1-yl)methanone
Show/Hide
|
C19H21Cl2N3O2
|
1
|
| 1 |
Ki = 78 nM
|
|
|
|
CP0400804
|
(6-(4-fluorophenoxy)pyridin-3-yl)(4-isopropylpiperazin-1-yl)methanone
Show/Hide
|
C19H22FN3O2
|
1
|
| 1 |
Ki = 79 nM
|
|
|
|
CP0522006
|
(2-Methoxy-ethyl)-[3-(3-piperidin-1-yl-propoxy)-isoxazol-5-ylmethyl]-amine
Show/Hide
|
C15H27N3O3
|
1
|
| 1 |
Ki = 79 nM
|
|
|
|
CP0878273
|
[4-(1H-imidazol-4-yl)-butyl]-iso-propyl-amine
Show/Hide
|
C10H19N3
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0431202
|
2-benzyl-1-[3-(1H-imidazol-5-yl)propyl]guanidine
Show/Hide
|
C14H19N5
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0373853
|
1-[4-[3-(pyrrolidin-1-ylmethyl)phenyl]but-3-ynyl]piperidine
Show/Hide
|
C20H28N2
|
1
|
| 1 |
Ki = 81.28 nM
|
|
|
|
CP0498418
|
1-[2-(4-piperidin-1-ylbut-1-ynyl)phenyl]piperidine
Show/Hide
|
C20H28N2
|
1
|
| 1 |
Ki = 83.18 nM
|
|
|
|
CP0452036
|
4-[3-(3-Piperidin-1-yl-propoxy)-isoxazol-5-ylmethyl]-morpholine
Show/Hide
|
C16H27N3O3
|
1
|
| 1 |
Ki = 85 nM
|
|
|
|
CP0060679
|
(4-isopropylpiperazin-1-yl)(3-(piperidin-1-ylmethyl)-1H-indol-5-yl)methanone
Show/Hide
|
C22H32N4O
|
1
|
| 1 |
Ki = 88 nM
|
|
|
|
CP0237145
|
(3-((4-isopropylpiperazin-1-yl)methyl)-1H-indol-6-yl)(piperidin-1-yl)methanone
Show/Hide
|
C22H32N4O
|
1
|
| 1 |
Ki = 88 nM
|
|
|
|
CP0846756
|
[4-(1H-imidazol-4-yl)-butyl]-diethyl-amine
Show/Hide
|
C11H21N3
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0438773
|
(6-(3-chlorophenoxy)pyridin-3-yl)(4-isopropylpiperazin-1-yl)methanone
Show/Hide
|
C19H22ClN3O2
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0511935
|
4-cyclopropyl-2-((4-(morpholinomethyl)phenoxy)methyl)morpholine
Show/Hide
|
C19H28N2O3
|
1
|
| 1 |
Ki = 106 nM
|
|
|
|
CP0522686
|
3-(5-(4-isopropylpiperazine-1-carbonyl)pyridin-2-yloxy)benzonitrile
Show/Hide
|
C20H22N4O2
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0475917
|
(4-Isopropyl-piperazin-1-yl)-(2-piperidin-1-ylmethylthiazol-4-yl)-methanone
Show/Hide
|
C17H28N4OS
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0530480
|
(4-Isopropyl-piperazin-1-yl)-(1-methyl-4-morpholin-4-ylmethyl-1H-pyrrol-2-yl)-methanone
Show/Hide
|
C18H30N4O2
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0400797
|
(4-cyclobutyl-1,4-diazepan-1-yl)(6-(3,4-dichlorophenoxy)pyridin-2-yl)methanone
Show/Hide
|
C21H23Cl2N3O2
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0549527
|
4-ethyl-2-((4-(morpholinomethyl)phenoxy)methyl)morpholine
Show/Hide
|
C18H28N2O3
|
1
|
| 1 |
Ki = 165 nM
|
|
|
|
CP0088872
|
(4-isopropylpiperazin-1-yl)(3-(morpholinomethyl)-1H-indol-5-yl)methanone
Show/Hide
|
C21H30N4O2
|
1
|
| 1 |
Ki = 180 nM
|
|
|
|
CP0522004
|
(4-Isopropyl-piperazin-1-yl)-(2-piperidin-1-ylmethyloxazol-4-yl)-methanone
Show/Hide
|
C17H28N4O2
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0533340
|
(4-isopropylpiperazin-1-yl)(6-(4-(methylthio)phenoxy)pyridin-3-yl)methanone
Show/Hide
|
C20H25N3O2S
|
1
|
| 1 |
Ki = 230 nM
|
|
|
|
CP0329087
|
(3-((4-cyclobutylpiperazin-1-yl)methyl)-1H-indol-7-yl)(piperidin-1-yl)methanone
Show/Hide
|
C23H32N4O
|
1
|
| 1 |
Ki = 240 nM
|
|
|
|
CP0386080
|
2-[4-[4-[(dipropylamino)methyl]phenyl]phenyl]-1-piperidin-1-ylethanone
Show/Hide
|
C26H36N2O
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0491037
|
(4-isopropylpiperazin-1-yl)(6-phenoxypyridin-3-yl)methanone
Show/Hide
|
C19H23N3O2
|
1
|
| 1 |
Ki = 260 nM
|
|
|
|
CP0847508
|
1-(3-(1H-imidazol-4-yl)propyl)-3-(2,2-diphenylvinyl)guanidine
Show/Hide
|
C21H23N5
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0475916
|
(4-Isopropyl-piperazin-1-yl)-{2-[(2-methoxy-ethylamino)-methyl]-thiazol-4-yl}-methanone
Show/Hide
|
C15H26N4O2S
|
1
|
| 1 |
Ki = 356 nM
|
|
|
|
CP0428189
|
1-[[4-[4-[(3,5-dimethylpiperidin-1-yl)methyl]phenyl]phenyl]methyl]-3,5-dimethylpiperidine
Show/Hide
|
C28H40N2
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0400803
|
(4-cyclopropylpiperazin-1-yl)(6-(4-fluorophenoxy)pyridin-3-yl)methanone
Show/Hide
|
C19H20FN3O2
|
1
|
| 1 |
Ki = 430 nM
|
|
|
|
CP0514094
|
(6-(3,4-dichlorophenoxy)pyridin-2-yl)(4-isopropyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C20H23Cl2N3O2
|
1
|
| 1 |
Ki = 430 nM
|
|
|
|
CP0475918
|
(4-Isopropyl-piperazin-1-yl)-{2-[(2-methoxy-ethylamino)-methyl]-oxazol-4-yl}-methanone
Show/Hide
|
C15H26N4O3
|
1
|
| 1 |
Ki = 458 nM
|
|
|
|
CP0423668
|
N-(2,2-dimethylpropyl)-4-[(3R)-3-[methyl(tritritiomethyl)amino]pyrrolidin-1-yl]pyrimidin-2-amine;2,2,2-trifluoroacetic acid
Show/Hide
|
C19H29F6N5O4
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0329089
|
(4-cyclobutylpiperazin-1-yl)(3-(piperidine-1-carbonyl)benzo[b]thiophen-5-yl)methanone
Show/Hide
|
C23H29N3O2S
|
1
|
| 1 |
Ki = 520 nM
|
|
|
|
CP0386084
|
N-[[4-[4-[(cyclohexylamino)methyl]phenyl]phenyl]methyl]cyclohexanamine
Show/Hide
|
C26H36N2
|
1
|
| 1 |
Ki = 562.34 nM
|
|
|
|
CP0468359
|
4-cyclopropyl-2-((3-(morpholinomethyl)phenoxy)methyl)morpholine
Show/Hide
|
C19H28N2O3
|
1
|
| 1 |
Ki = 566 nM
|
|
|
|
CP0935743
|
1-[4-(3-Cyclohexyl-propoxy)-benzyl]-piperidine
Show/Hide
|
C21H33NO
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0849116
|
tert-Butyl-[4-(1H-imidazol-4-yl)-butyl]-amine
Show/Hide
|
C11H21N3
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0247768
|
4-ethyl-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine
Show/Hide
|
C11H19N5
|
1
|
| 1 |
Ki = 670 nM
|
|
|
|
CP0459510
|
(4-Isopropyl-piperazin-1-yl)-(2-morpholin-4-ylmethylthiazol-4-yl)-methanone
Show/Hide
|
C16H26N4O2S
|
1
|
| 1 |
Ki = 679 nM
|
|
|
|
CP0478512
|
(4-Isopropyl-piperazin-1-yl)-(2-morpholin-4-ylmethyloxazol-4-yl)-methanone
Show/Hide
|
C16H26N4O3
|
1
|
| 1 |
Ki = 692 nM
|
|
|
|
CP0381644
|
N-[[4-[4-[(pentylamino)methyl]phenyl]phenyl]methyl]pentan-1-amine
Show/Hide
|
C24H36N2
|
1
|
| 1 |
Ki = 758.58 nM
|
|
|
|
CP0533339
|
(6-(4-fluorophenoxy)pyridin-3-yl)(4-methyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C18H20FN3O2
|
1
|
| 1 |
Ki = 860 nM
|
|
|
|
CP0430781
|
(4-cyclopropyl-1,4-diazepan-1-yl)(6-(3,4-dichlorophenoxy)pyridin-2-yl)methanone
Show/Hide
|
C20H21Cl2N3O2
|
1
|
| 1 |
Ki = 1040 nM
|
|
|
|
CP0058845
|
4-[(3R)-3-aminopyrrolidin-1-yl]-6-propan-2-ylpyrimidin-2-amine
Show/Hide
|
C11H19N5
|
1
|
| 1 |
Ki = 1043 nM
|
|
|
|
CP0304548
|
1-[[4-(piperidin-1-ylmethyl)phenyl]methyl]piperidine
Show/Hide
|
C18H28N2
|
1
|
| 1 |
Ki = 1230.27 nM
|
|
|
|
CP0386067
|
1-[4-[[4-[4-[(4-acetylpiperazin-1-yl)methyl]phenyl]phenyl]methyl]piperazin-1-yl]ethanone
Show/Hide
|
C26H34N4O2
|
1
|
| 1 |
Ki = 1412.54 nM
|
|
|
|
CP0423535
|
4-methyl-2-((4-(morpholinomethyl)phenoxy)methyl)morpholine
Show/Hide
|
C17H26N2O3
|
1
|
| 1 |
Ki = 2100 nM
|
|
|
|
CP0294507
|
(3-(morpholinomethyl)-1H-indol-7-yl)(piperazin-1-yl)methanone
Show/Hide
|
C18H24N4O2
|
1
|
| 1 |
Ki = 2130 nM
|
|
|
|
CP0505481
|
(NZ)-N-[1H-indol-2-yl-(1-methylpiperidin-4-yl)methylidene]hydroxylamine
Show/Hide
|
C15H19N3O
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0276308
|
(4-isopropylpiperazin-1-yl)(3-(piperidine-1-carbonyl)benzo[b]thiophen-5-yl)methanone
Show/Hide
|
C22H29N3O2S
|
1
|
| 1 |
Ki = 3280 nM
|
|
|
|
CP0307262
|
N-butyl-N-[3-[4-(5-methylimidazo[1,2-a]pyridin-2-yl)phenoxy]propyl]butan-1-amine
Show/Hide
|
C25H35N3O
|
1
|
| 1 |
Ki = 4000 nM
|
|
|
|
CP0288400
|
C-(4'-aminomethyl-biphenyl-4-yl)-methylamine
Show/Hide
|
C14H16N2
|
1
|
| 1 |
Ki = 4466.84 nM
|
|
|
|
CP0384613
|
4-isopropyl-2-(phenoxymethyl)morpholine
Show/Hide
|
C14H21NO2
|
1
|
| 1 |
Ki = 4800 nM
|
|
|
|
CP0302873
|
(4-isopropylpiperazin-1-yl)(3-(morpholinomethyl)-1H-indol-4-yl)methanone
Show/Hide
|
C21H30N4O2
|
1
|
| 1 |
Ki = 4900 nM
|
|
|
|
CP0778443
|
5-Chloro-1H-indole-2-carboxylic acid (2-dimethylamino-ethyl)-amide
Show/Hide
|
C13H16ClN3O
|
1
|
| 1 |
Ki = 5011.87 nM
|
|
|
|
CP0504913
|
4-cyclopentyl-2-((2-ethoxyphenoxy)methyl)morpholine
Show/Hide
|
C18H27NO3
|
1
|
| 1 |
Ki = 5300 nM
|
|
|
|
CP0398855
|
2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine
Show/Hide
|
C6H11N3
|
1
|
| 1 |
Ki = 6309.57 nM
|
|
|
|
CP0497869
|
4-cyclobutyl-2-((2-ethoxyphenoxy)methyl)morpholine
Show/Hide
|
C17H25NO3
|
1
|
| 1 |
Ki = 7100 nM
|
|
|
|
CP0035258
|
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
Show/Hide
|
C17H18F3NO
|
1
|
| 1 |
Ki = 7300 nM
|
|
|
|
CP0099909
|
1-cyano-3-[[(2R,5S)-5-(1H-imidazol-5-yl)oxolan-2-yl]methyl]-2-methylguanidine
Show/Hide
|
C11H16N6O
|
1
|
| 1 |
Ki = 7943.28 nM
|
|
|
|
CP0497868
|
2-((2-ethoxyphenoxy)methyl)-4-isopropylmorpholine
Show/Hide
|
C16H25NO3
|
1
|
| 1 |
Ki = 9000 nM
|
|
|
|
CP0477746
|
(1,4-diazepan-1-yl)(6-(4-fluorophenoxy)pyridin-3-yl)methanone
Show/Hide
|
C17H18FN3O2
|
1
|
| 1 |
Ki = 9000 nM
|
|
|
|
CP0180153
|
7-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepine
Show/Hide
|
C18H18ClN3O
|
1
|
| 1 |
Ki = 9120.11 nM
|
|
|
|
CP0511937
|
4-cyclopropyl-2-((2-ethoxyphenoxy)methyl)morpholine
Show/Hide
|
C16H23NO3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0553656
|
2-(phenoxymethyl)morpholine
Show/Hide
|
C11H15NO2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0394508
|
(NZ)-N-[(5-methyl-1H-indol-2-yl)-(1-methylpiperidin-4-yl)methylidene]hydroxylamine
Show/Hide
|
C16H21N3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0412802
|
(NZ)-N-[(6-chloro-1H-benzimidazol-2-yl)-(1-methylpiperidin-4-yl)methylidene]hydroxylamine
Show/Hide
|
C14H17ClN4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0439321
|
(NZ)-N-[(5-chloro-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methylidene]hydroxylamine
Show/Hide
|
C14H17ClN4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0392160
|
1-[[4-(4-pentylphenyl)phenyl]methyl]piperidine
Show/Hide
|
C23H31N
|
1
|
| 1 |
Ki = 12882.5 nM
|
|
|
|
CP0461873
|
1-[1-[4-(4-methylphenyl)phenyl]pentyl]piperidine
Show/Hide
|
C23H31N
|
1
|
| 1 |
Ki = 13489.63 nM
|
|
|
