Brief Information of the Compound and Protein
Compound Name
4-(3-methoxyphenyl)-2-methyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine
    Show/Hide
PubChem ID
CID: 15983578
SID: 24262596
Canonical SMILES
COc1cccc(c1)C1CN(C)Cc2cc(OCCCN3CCCCC3)ncc12
    Show/Hide
Compound Formula C24H33N3O2
Compound Structure
Protein Name
Histamine H3 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  2
1
Kd = 25.7 nM
   TI
   LI
   LO
   TS
2
Ki = 8 nM
   TI
   LI
   LO
   TS