Cell Line Information

General Information of the Cell Line

Cell Line ID	CL000074
Cell Line Name	SK-N-MC
Synonyms	SKNMC SK-NM-C SK-NMC
Category	Cancer cell line
Organism	Homo sapiens (Human)
Cellosaurus ID	CVCL_0530
Tissue Information	Orbital region
Disease	Askin tumor (NCIt: C7542) Peripheral primitive neuroectodermal tumor (ORDO: Orphanet_370348)

Map of Molecular Bioactivity Related to the Cell Line

Map of Molecular Bioactivity Related to the Cell Line Cell Line Protein Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Cell Line

Protein ID: PT01670, Calcitonin gene-related peptide type 1 receptor

Protein Info

Compound ID	Compound Name	Compound Formula
CP0076148 Compound Info	[(5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl] 4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate Show/Hide	C28H28F2N6O3	2
1	EC50 = 0.14 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.027 nM Bioactivity Info	TI LI LO TS
CP0124034 Compound Info	N-[(2R)-3-(1-benzothiophen-3-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-2-oxospiro[1,3-dihydroquinazoline-4,4'-piperidine]-1'-carboxamide Show/Hide	C34H42N6O3S	2
1	EC50 = 3 nM Bioactivity Info	TI LI LO TS
2	IC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0492355 Compound Info	N-[(2R)-3-(1-benzothiophen-3-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-2-oxospiro[1,3-dihydroquinoline-4,4'-piperidine]-1'-carboxamide Show/Hide	C35H43N5O3S	2
1	EC50 = 12 nM Bioactivity Info	TI LI LO TS
2	IC50 = 23 nM Bioactivity Info	TI LI LO TS
CP0338333 Compound Info	N-[(2R)-3-(1-benzothiophen-3-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-oxo-2-phenyl-1,3,8-triazaspiro[4.5]dec-1-ene-8-carboxamide Show/Hide	C35H42N6O3S	2
1	EC50 = 13 nM Bioactivity Info	TI LI LO TS
2	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0428998 Compound Info	N-[(2R)-3-(1-benzothiophen-3-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-3-oxospiro[2,4-dihydroisoquinoline-1,4'-piperidine]-1'-carboxamide Show/Hide	C35H43N5O3S	2
1	EC50 = 15 nM Bioactivity Info	TI LI LO TS
2	IC50 = 29 nM Bioactivity Info	TI LI LO TS
CP0114078 Compound Info	N-[(2R)-3-(1-benzothiophen-3-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-2-oxospiro[1H-3,1-benzoxazine-4,4'-piperidine]-1'-carboxamide Show/Hide	C34H41N5O4S	2
1	EC50 = 31 nM Bioactivity Info	TI LI LO TS
2	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0513149 Compound Info	N-[(2R)-3-(1-benzothiophen-3-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-1-oxospiro[2,3-dihydroisoquinoline-4,4'-piperidine]-1'-carboxamide Show/Hide	C35H43N5O3S	2
1	EC50 = 130 nM Bioactivity Info	TI LI LO TS
2	IC50 = 150 nM Bioactivity Info	TI LI LO TS
CP0481070 Compound Info	(2S)-2-[(7-methyl-1H-indazol-5-yl)methyl]-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C36H47N7O3	2
1	IC50 = 0.019 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.06 nM Bioactivity Info	TI LI LO TS
CP0408833 Compound Info	[2-(7-methyl-1H-indazol-5-yl)-1-[4-(piperidin-1-ylmethyl)pyridin-2-yl]ethyl] 4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate Show/Hide	C35H41N7O3	2
1	IC50 = 0.02 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.1 nM Bioactivity Info	TI LI LO TS
CP0000982 Compound Info	N-[(2R)-1-[[(2S)-6-amino-1-oxo-1-(4-pyridin-4-ylpiperazin-1-yl)hexan-2-yl]amino]-3-(3,5-dibromo-4-hydroxyphenyl)-1-oxopropan-2-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C38H47Br2N9O5	3
1	IC50 = 0.02 nM Bioactivity Info	TI LI LO TS
2	IC50 = 4 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.01 nM Bioactivity Info	TI LI LO TS
CP0184709 Compound Info	(R)-4-(8-Fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl)piperidin-1-yl)propan-2-yl)piperidine-1-carboxamide Show/Hide	C35H45FN8O3	2
1	IC50 = 0.026 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.013 nM Bioactivity Info	TI LI LO TS
CP0436219 Compound Info	4-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidine-1-carboxylic acid [(S)-1-[(R)-5-amino-1-(4-pyridin-4-yl-piperazine-1-carbonyl)-pentylcarbamoyl]-2-(3,5-dibromo-4-hydroxy-phenyl)-ethyl]-amide Show/Hide	C38H47Br2N9O5	1
1	IC50 = 0.03 nM Bioactivity Info	TI LI LO TS
CP0517281 Compound Info	[1-[4-(azepan-1-ylmethyl)pyridin-2-yl]-2-(7-methyl-1H-indazol-5-yl)ethyl] 4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxylate Show/Hide	C37H42N6O3	2
1	IC50 = 0.042 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.095 nM Bioactivity Info	TI LI LO TS
CP0566747 Compound Info	2-[(7-methyl-1H-indazol-5-yl)methyl]-4-[4-(2-oxo-5-phenyl-1H-imidazol-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C37H47N7O3	2
1	IC50 = 0.049 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.15 nM Bioactivity Info	TI LI LO TS
CP0431517 Compound Info	4-(2-Oxo-4-phenyl-2,3-dihydro-imidazol-1-yl)-piperidine-1-carboxylic acid [(S)-1-[(R)-5-amino-1-(4-pyridin-4-yl-piperazine-1-carbonyl)-pentylcarbamoyl]-2-(3,5-dibromo-4-hydroxy-phenyl)-ethyl]-amide Show/Hide	C39H47Br2N9O5	1
1	IC50 = 0.05 nM Bioactivity Info	TI LI LO TS
CP0911096 Compound Info	(S)-4-Chloro-1-methyl-7-{2-oxo-2-[4-(2-oxo-1,2,4,5-tetrahydro-benzo[d][1,3]diazepin-3-yl)-piperidin-1-yl]-ethyl}-9-(2,2,2-trifluoro-ethyl)-1,3,6,7,9,10-hexahydro-1,3,9-triaza-cyclohepta[e]indene-2,8-dione Show/Hide	C30H32ClF3N6O4	2
1	IC50 = 0.06 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.015 nM Bioactivity Info	TI LI LO TS
CP0525112 Compound Info	[(1R)-1-[6-chloro-4-(dimethylcarbamoyl)pyridin-2-yl]-2-(7-methyl-1H-indazol-5-yl)ethyl] 4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxylate Show/Hide	C33H33ClN6O4	2
1	IC50 = 0.064 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.077 nM Bioactivity Info	TI LI LO TS
CP0928613 Compound Info	rac-1-(1,4'-bipiperidin-1'-yl)-2-((7-methyl-1H-indazol-5-yl)methyl)-4-(4-(2-oxo-1,2-dihydroquinazolin-3(4H)-yl)piperidin-1-yl)butane-1,4-dione Show/Hide	C36H47N7O3	2
1	IC50 = 0.068 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.074 nM Bioactivity Info	TI LI LO TS
CP0400118 Compound Info	[1-[6-chloro-4-(dimethylcarbamoyl)pyridin-2-yl]-2-(7-methyl-1H-indazol-5-yl)ethyl] 4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate Show/Hide	C30H31ClN8O4	2
1	IC50 = 0.071 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.18 nM Bioactivity Info	TI LI LO TS
CP0538969 Compound Info	N-[1-[1-[(2-chloro-6-methylpyridin-4-yl)methyl]imidazol-2-yl]-2-(7-methyl-1H-indazol-5-yl)ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C34H36ClN9O2	1
1	IC50 = 0.078 nM Bioactivity Info	TI LI LO TS
CP0389936 Compound Info	(2S)-4-[4-(8-fluoro-2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-2-[(7-methyl-1H-indazol-5-yl)methyl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C36H46FN7O3	2
1	IC50 = 0.082 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.2 nM Bioactivity Info	TI LI LO TS
CP0481069 Compound Info	4-[4-(8-fluoro-2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-2-[(7-methyl-1H-indazol-5-yl)methyl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C36H46FN7O3	2
1	IC50 = 0.089 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.18 nM Bioactivity Info	TI LI LO TS
CP0914648 Compound Info	(S)-4-Chloro-1-ethyl-7-{2-oxo-2-[4-(2-oxo-1,2,4,5-tetrahydro-benzo[d][1,3]diazepin-3-yl)-piperidin-1-yl]-ethyl}-9-(2,2,2-trifluoro-ethyl)-1,3,6,7,9,10-hexahydro-1,3,9-triaza-cyclohepta[e]indene-2,8-dione Show/Hide	C31H34ClF3N6O4	2
1	IC50 = 0.09 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.014 nM Bioactivity Info	TI LI LO TS
CP0548634 Compound Info	[1-[6-chloro-4-(dimethylcarbamoyl)pyridin-2-yl]-2-(7-methyl-1H-indazol-5-yl)ethyl] 4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidine-1-carboxylate Show/Hide	C33H36ClN7O4	1
1	IC50 = 0.093 nM Bioactivity Info	TI LI LO TS
CP0537730 Compound Info	[2-(7-methyl-1H-indazol-5-yl)-1-[4-(piperidine-1-carbonyl)pyridin-2-yl]ethyl] 4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate Show/Hide	C35H39N7O4	2
1	IC50 = 0.099 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.28 nM Bioactivity Info	TI LI LO TS
CP0450869 Compound Info	[2-(7-methyl-1H-indazol-5-yl)-1-[4-(piperidin-1-ylmethyl)pyridin-2-yl]ethyl] 4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxylate Show/Hide	C36H40N6O3	2
1	IC50 = 0.1 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.16 nM Bioactivity Info	TI LI LO TS
CP0488116 Compound Info	2-[(7-methyl-1H-indazol-5-yl)methyl]-4-[4-(2-oxo-1H-quinolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C37H46N6O3	2
1	IC50 = 0.12 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.3 nM Bioactivity Info	TI LI LO TS
CP0952876 Compound Info	(S)-4-Chloro-7-{2-oxo-2-[4-(2-oxo-1,2,4,5-tetrahydro-benzo[d][1,3]diazepin-3-yl)-piperidin-1-yl]-ethyl}-1,9-bis-(2,2,2-trifluoro-ethyl)-1,3,6,7,9,10-hexahydro-1,3,9-triaza-cyclohepta[e]indene-2,8-dione Show/Hide	C31H31ClF6N6O4	2
1	IC50 = 0.12 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.02 nM Bioactivity Info	TI LI LO TS
CP0482492 Compound Info	N-[2-(7-methyl-1H-indazol-5-yl)-1-[1-[(2-methylpyridin-4-yl)methyl]imidazol-2-yl]ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C34H37N9O2	1
1	IC50 = 0.13 nM Bioactivity Info	TI LI LO TS
CP0414762 Compound Info	N-[1-[1-[(4-tert-butylphenyl)methyl]imidazol-2-yl]-2-(7-methyl-1H-indazol-5-yl)ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C38H44N8O2	1
1	IC50 = 0.19 nM Bioactivity Info	TI LI LO TS
CP0476072 Compound Info	4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidine-1-carboxylic acid [(S)-1-[(R)-5-amino-1-(4-pyridin-4-yl-piperazine-1-carbonyl)-pentylcarbamoyl]-2-(3,5-dibromo-4-hydroxy-phenyl)-ethyl]-amide Show/Hide	C37H45Br2N9O5	2
1	IC50 = 0.2 nM Bioactivity Info	TI LI LO TS
2	Kd = 0.07943 nM Bioactivity Info	TI LI LO TS
CP0428373 Compound Info	[1-(4-formylpyridin-2-yl)-2-(7-methyl-1H-indazol-5-yl)ethyl] 4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate Show/Hide	C30H30N6O4	2
1	IC50 = 0.21 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.28 nM Bioactivity Info	TI LI LO TS
CP0533009 Compound Info	[1-(7-cyclohexyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-3-yl)-2-(7-methyl-1H-indazol-5-yl)ethyl] 4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxylate Show/Hide	C37H43N7O3	1
1	IC50 = 0.22 nM Bioactivity Info	TI LI LO TS
CP0400341 Compound Info	[2-(7-methyl-1H-indazol-5-yl)-1-[4-(pyrrolidin-1-ylmethyl)pyridin-2-yl]ethyl] 4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxylate Show/Hide	C35H38N6O3	1
1	IC50 = 0.24 nM Bioactivity Info	TI LI LO TS
CP0548280 Compound Info	[2-(7-methyl-3-phenyl-2H-indazol-5-yl)-1-pyridin-2-ylethyl] 4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate Show/Hide	C35H34N6O3	1
1	IC50 = 0.24 nM Bioactivity Info	TI LI LO TS
CP0533008 Compound Info	[1-(7-benzyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-3-yl)-2-(7-methyl-1H-indazol-5-yl)ethyl] 4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxylate Show/Hide	C38H39N7O3	1
1	IC50 = 0.26 nM Bioactivity Info	TI LI LO TS
CP0428375 Compound Info	[2-(7-methyl-1H-indazol-5-yl)-1-(4-pyridin-4-ylpyridin-2-yl)ethyl] 4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate Show/Hide	C34H33N7O3	1
1	IC50 = 0.27 nM Bioactivity Info	TI LI LO TS
CP0400115 Compound Info	[1-[6-chloro-4-(dimethylcarbamoyl)pyridin-2-yl]-2-(7-methyl-1H-indazol-5-yl)ethyl] 4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxylate Show/Hide	C33H33ClN6O4	3
1	IC50 = 0.28 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.34 nM Bioactivity Info	TI LI LO TS
3	Ki = 3.3 nM Bioactivity Info	TI LI LO TS
CP0467320 Compound Info	3-(3,3-dimethylbutyl)-2-[3-fluoro-2-(4-propan-2-ylpiperazin-1-yl)phenyl]-5-[2-oxo-2-[4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C38H53FN6O3S	2
1	IC50 = 0.3 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.02 nM Bioactivity Info	TI LI LO TS
CP0499039 Compound Info	2-[(7-methyl-1H-indazol-5-yl)methyl]-4-(2-oxospiro[1H-3,1-benzoxazine-4,4'-piperidine]-1'-yl)-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C35H44N6O4	2
1	IC50 = 0.33 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.7 nM Bioactivity Info	TI LI LO TS
CP0408838 Compound Info	[2-(3-bromo-7-methyl-2H-indazol-5-yl)-1-pyridin-2-ylethyl] 4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate Show/Hide	C29H29BrN6O3	1
1	IC50 = 0.33 nM Bioactivity Info	TI LI LO TS
CP0525063 Compound Info	[1-[4-(dimethylcarbamoyl)pyridin-2-yl]-2-(7-methyl-1H-indazol-5-yl)ethyl] 4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate Show/Hide	C32H35N7O4	1
1	IC50 = 0.33 nM Bioactivity Info	TI LI LO TS
CP0430769 Compound Info	2-[(7-methyl-1H-indazol-5-yl)methyl]-4-(2-oxospiro[1,3-dihydroquinazoline-4,4'-piperidine]-1'-yl)-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C35H45N7O3	2
1	IC50 = 0.34 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.35 nM Bioactivity Info	TI LI LO TS
CP0414761 Compound Info	N-[1-[1-[(3-fluorophenyl)methyl]-5-methylimidazol-2-yl]-2-(7-methyl-1H-indazol-5-yl)ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C35H37FN8O2	1
1	IC50 = 0.37 nM Bioactivity Info	TI LI LO TS
CP0513778 Compound Info	[1-(6-bromopyridin-2-yl)-2-(7-methyl-1H-indazol-5-yl)ethyl] 4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate Show/Hide	C29H29BrN6O3	2
1	IC50 = 0.38 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.46 nM Bioactivity Info	TI LI LO TS
CP0400342 Compound Info	[2-(3-chloro-7-methyl-2H-indazol-5-yl)-1-pyridin-2-ylethyl] 4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate Show/Hide	C29H29ClN6O3	1
1	IC50 = 0.39 nM Bioactivity Info	TI LI LO TS
CP0482428 Compound Info	N-[1-[1-[(3,5-difluorophenyl)methyl]imidazol-2-yl]-2-(7-methyl-1H-indazol-5-yl)ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C34H34F2N8O2	1
1	IC50 = 0.39 nM Bioactivity Info	TI LI LO TS
CP0491726 Compound Info	N-[1-[4-bromo-1-[(3,5-difluorophenyl)methyl]imidazol-2-yl]-2-(7-methyl-1H-indazol-5-yl)ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C34H33BrF2N8O2	1
1	IC50 = 0.39 nM Bioactivity Info	TI LI LO TS
CP0482493 Compound Info	N-[2-(7-methyl-1H-indazol-5-yl)-1-[1-(pyridin-3-ylmethyl)imidazol-2-yl]ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C33H35N9O2	1
1	IC50 = 0.42 nM Bioactivity Info	TI LI LO TS
CP0482029 Compound Info	[1-isoquinolin-3-yl-2-(7-methyl-1H-indazol-5-yl)ethyl] 4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate Show/Hide	C33H32N6O3	2
1	IC50 = 0.46 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.63 nM Bioactivity Info	TI LI LO TS
CP0400116 Compound Info	N-[1-(6-bromopyridin-2-yl)-2-(7-methyl-1H-indazol-5-yl)ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C29H30BrN7O2	2
1	IC50 = 0.49 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.82 nM Bioactivity Info	TI LI LO TS
CP0467319 Compound Info	2-[2-(4-tert-butylpiperazin-1-yl)-3-fluorophenyl]-3-(3,3-dimethylbutyl)-5-[2-oxo-2-[4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C39H55FN6O3S	2
1	IC50 = 0.6 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.1 nM Bioactivity Info	TI LI LO TS
CP0414763 Compound Info	N-[1-[1-[(3-fluorophenyl)methyl]imidazol-2-yl]-2-(7-methyl-1H-indazol-5-yl)ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C34H35FN8O2	1
1	IC50 = 0.63 nM Bioactivity Info	TI LI LO TS
CP0482430 Compound Info	N-[1-(1-benzylimidazol-2-yl)-2-(7-methyl-1H-indazol-5-yl)ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C34H36N8O2	1
1	IC50 = 0.77 nM Bioactivity Info	TI LI LO TS
CP0400338 Compound Info	N-[1-isoquinolin-3-yl-2-(7-methyl-1H-indazol-5-yl)ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C33H33N7O2	2
1	IC50 = 0.82 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1 nM Bioactivity Info	TI LI LO TS
CP0395548 Compound Info	N-[2-(7-methyl-1H-indazol-5-yl)-1-[1-(pyridin-4-ylmethyl)imidazol-2-yl]ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C33H35N9O2	1
1	IC50 = 0.83 nM Bioactivity Info	TI LI LO TS
CP0459298 Compound Info	N-[2-(7-methyl-1H-indazol-5-yl)-1-[1-(2-phenylethyl)imidazol-2-yl]ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C35H38N8O2	1
1	IC50 = 0.88 nM Bioactivity Info	TI LI LO TS
CP0400343 Compound Info	6-[1-(7-methyl-1H-indazol-5-yl)-4-oxo-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]butan-2-yl]pyridine-3-carbaldehyde Show/Hide	C31H32N6O3	2
1	IC50 = 0.94 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1.1 nM Bioactivity Info	TI LI LO TS
CP0414765 Compound Info	N-[1-[1-[(4-fluorophenyl)methyl]imidazol-2-yl]-2-(7-methyl-1H-indazol-5-yl)ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C34H35FN8O2	1
1	IC50 = 0.98 nM Bioactivity Info	TI LI LO TS
CP0471460 Compound Info	(2R,5S)-2-[2-(4-tert-butylpiperazin-1-yl)-3-fluorophenyl]-3-(3,3-dimethylbutyl)-5-[2-oxo-2-[4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C39H55FN6O3S	2
1	IC50 = 1 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.03 nM Bioactivity Info	TI LI LO TS
CP0450868 Compound Info	[2-(7-methyl-1H-indazol-5-yl)-1-[4-(morpholin-4-ylmethyl)pyridin-2-yl]ethyl] 4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxylate Show/Hide	C35H38N6O4	1
1	IC50 = 1.2 nM Bioactivity Info	TI LI LO TS
CP0513779 Compound Info	[2-(3-formyl-7-methyl-2H-indazol-5-yl)-1-pyridin-2-ylethyl] 4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate Show/Hide	C30H30N6O4	1
1	IC50 = 1.3 nM Bioactivity Info	TI LI LO TS
CP0408840 Compound Info	3-[1-[4-(7-methyl-1H-indazol-5-yl)-3-[5-(piperidin-1-ylmethyl)pyridin-2-yl]butanoyl]piperidin-4-yl]-1,4-dihydroquinazolin-2-one Show/Hide	C36H43N7O2	2
1	IC50 = 1.3 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1.8 nM Bioactivity Info	TI LI LO TS
CP0526159 Compound Info	[2-(7-methyl-1H-indazol-5-yl)-1-quinolin-2-ylethyl] 4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate Show/Hide	C33H32N6O3	2
1	IC50 = 1.4 nM Bioactivity Info	TI LI LO TS
2	IC50 = 4.8 nM Bioactivity Info	TI LI LO TS
CP0400337 Compound Info	N-[2-(7-methyl-1H-indazol-5-yl)-1-quinolin-2-ylethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C33H33N7O2	2
1	IC50 = 1.4 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2 nM Bioactivity Info	TI LI LO TS
CP0527352 Compound Info	[2-(7-methyl-1H-indazol-5-yl)-1-pyridin-2-ylethyl] 4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate Show/Hide	C29H30N6O3	2
1	IC50 = 1.5 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1.9 nM Bioactivity Info	TI LI LO TS
CP0533010 Compound Info	N-[2-(7-methyl-1H-indazol-5-yl)-1-[1-(pyridin-2-ylmethyl)imidazol-2-yl]ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C33H35N9O2	1
1	IC50 = 1.6 nM Bioactivity Info	TI LI LO TS
CP0459297 Compound Info	[1-(7-ethyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-3-yl)-2-(7-methyl-1H-indazol-5-yl)ethyl] 4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxylate Show/Hide	C33H37N7O3	1
1	IC50 = 1.7 nM Bioactivity Info	TI LI LO TS
CP0527351 Compound Info	[2-[7-methyl-3-(morpholin-4-ylmethyl)-2H-indazol-5-yl]-1-pyridin-2-ylethyl] 4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate Show/Hide	C34H39N7O4	1
1	IC50 = 1.9 nM Bioactivity Info	TI LI LO TS
CP0395549 Compound Info	N-[1-[1-[(2-fluorophenyl)methyl]imidazol-2-yl]-2-(7-methyl-1H-indazol-5-yl)ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C34H35FN8O2	1
1	IC50 = 1.9 nM Bioactivity Info	TI LI LO TS
CP0399633 Compound Info	2-[(7-methyl-1H-indazol-5-yl)methyl]-1-(4-methylpiperidin-1-yl)-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]butane-1,4-dione Show/Hide	C32H40N6O3	2
1	IC50 = 2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2.7 nM Bioactivity Info	TI LI LO TS
CP0537731 Compound Info	[1-[4-(hydroxymethyl)pyridin-2-yl]-2-(7-methyl-1H-indazol-5-yl)ethyl] 4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate Show/Hide	C30H32N6O4	2
1	IC50 = 2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2.1 nM Bioactivity Info	TI LI LO TS
CP0443518 Compound Info	3-(3,3-dimethylbutyl)-2-[2-(4-ethylpiperazin-1-yl)-3-fluorophenyl]-5-[2-oxo-2-[4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C37H51FN6O3S	2
1	IC50 = 2 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.07 nM Bioactivity Info	TI LI LO TS
CP0395547 Compound Info	[2-(7-methyl-1H-indazol-5-yl)-1-(5,6,7,8-tetrahydroimidazo[1,5-a]pyrazin-3-yl)ethyl] 4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxylate Show/Hide	C31H33N7O3	1
1	IC50 = 2.9 nM Bioactivity Info	TI LI LO TS
CP0524274 Compound Info	[1-(4-cyanopyridin-2-yl)-2-(7-methyl-1H-indazol-5-yl)ethyl] 4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate Show/Hide	C30H29N7O3	1
1	IC50 = 3 nM Bioactivity Info	TI LI LO TS
CP0406123 Compound Info	(R)-N-(1-(1,4'-bipiperidin-1'-yl)-3-(benzo[b]thiophen-3-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinazolin-3(4H)-yl)piperidine-1-carboxamide Show/Hide	C35H44N6O3S	1
1	IC50 = 3 nM Bioactivity Info	TI LI LO TS
CP0443683 Compound Info	3-(3,3-dimethylbutyl)-2-[3-fluoro-2-(4-methylpiperazin-1-yl)phenyl]-5-[2-oxo-2-[4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C36H49FN6O3S	2
1	IC50 = 3 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.5 nM Bioactivity Info	TI LI LO TS
CP0517505 Compound Info	N-[2-(7-methyl-1H-indazol-5-yl)-1-pyridin-2-ylethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C29H31N7O2	2
1	IC50 = 3.1 nM Bioactivity Info	TI LI LO TS
2	IC50 = 4.1 nM Bioactivity Info	TI LI LO TS
CP0499052 Compound Info	1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-2-[(7-methyl-1H-indazol-5-yl)methyl]-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]butane-1,4-dione Show/Hide	C33H40N6O5	2
1	IC50 = 3.2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 5.8 nM Bioactivity Info	TI LI LO TS
CP0400339 Compound Info	N-[2-(7-methyl-1H-indazol-5-yl)-1-(6-methylpyridin-2-yl)ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C30H33N7O2	2
1	IC50 = 3.4 nM Bioactivity Info	TI LI LO TS
2	IC50 = 3.8 nM Bioactivity Info	TI LI LO TS
CP0389935 Compound Info	2-[(7-methyl-1H-indazol-5-yl)methyl]-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-piperidin-1-ylbutane-1,4-dione Show/Hide	C31H38N6O3	2
1	IC50 = 3.7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 6.9 nM Bioactivity Info	TI LI LO TS
CP0544581 Compound Info	N-[(2R)-3-(1-benzothiophen-3-yl)-1-oxo-1-(4-piperidin-4-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide Show/Hide	C34H42N6O3S	1
1	IC50 = 4 nM Bioactivity Info	TI LI LO TS
CP0387856 Compound Info	(2R,5S)-3-(3,3-dimethylbutyl)-2-[2-(4-methylpiperazin-1-yl)phenyl]-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C35H48N6O3S	2
1	IC50 = 4 nM Bioactivity Info	TI LI LO TS
2	Ki = 2 nM Bioactivity Info	TI LI LO TS
CP0400340 Compound Info	methyl 2-[2-(7-methyl-1H-indazol-5-yl)-1-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carbonyl]oxyethyl]pyridine-4-carboxylate Show/Hide	C31H32N6O5	1
1	IC50 = 4.4 nM Bioactivity Info	TI LI LO TS
CP0428370 Compound Info	3-[1-[4-(7-methyl-1H-indazol-5-yl)-3-(3-methylpyridin-2-yl)butanoyl]piperidin-4-yl]-1,4-dihydroquinazolin-2-one Show/Hide	C31H34N6O2	2
1	IC50 = 4.4 nM Bioactivity Info	TI LI LO TS
2	IC50 = 8.2 nM Bioactivity Info	TI LI LO TS
CP0399634 Compound Info	(2R)-4-[4-(8-fluoro-2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-2-[(7-methyl-1H-indazol-5-yl)methyl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C36H46FN7O3	2
1	IC50 = 4.6 nM Bioactivity Info	TI LI LO TS
2	IC50 = 6.7 nM Bioactivity Info	TI LI LO TS
CP0431516 Compound Info	4-(1-Phenyl-ureido)-piperidine-1-carboxylic acid [(S)-1-[(R)-5-amino-1-(4-pyridin-4-yl-piperazine-1-carbonyl)-pentylcarbamoyl]-2-(3,5-dibromo-4-hydroxy-phenyl)-ethyl]-amide Show/Hide	C37H47Br2N9O5	2
1	IC50 = 4.7 nM Bioactivity Info	TI LI LO TS
2	Kd = 0.7943 nM Bioactivity Info	TI LI LO TS
CP0405916 Compound Info	N-[1-(4,5-dibromo-1H-imidazol-2-yl)-2-(7-methyl-1H-indazol-5-yl)ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C27H28Br2N8O2	1
1	IC50 = 4.8 nM Bioactivity Info	TI LI LO TS
CP0459299 Compound Info	N-[1-(1-methylimidazol-2-yl)-2-(7-methyl-1H-indazol-5-yl)ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C28H32N8O2	1
1	IC50 = 4.8 nM Bioactivity Info	TI LI LO TS
CP0414426 Compound Info	1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-2-[(7-methyl-1H-indazol-5-yl)methyl]-4-(2-oxospiro[1H-3,1-benzoxazine-4,4'-piperidine]-1'-yl)butane-1,4-dione Show/Hide	C32H37N5O6	2
1	IC50 = 5.9 nM Bioactivity Info	TI LI LO TS
2	IC50 = 8.8 nM Bioactivity Info	TI LI LO TS
CP0447779 Compound Info	3-[1-[3-[5-(hydroxymethyl)pyridin-2-yl]-4-(7-methyl-1H-indazol-5-yl)butanoyl]piperidin-4-yl]-1,4-dihydroquinazolin-2-one Show/Hide	C31H34N6O3	2
1	IC50 = 6 nM Bioactivity Info	TI LI LO TS
2	IC50 = 7.9 nM Bioactivity Info	TI LI LO TS
CP0525099 Compound Info	[2-[7-methyl-3-(piperidin-1-ylmethyl)-2H-indazol-5-yl]-1-pyridin-2-ylethyl] 4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate Show/Hide	C35H41N7O3	1
1	IC50 = 6.6 nM Bioactivity Info	TI LI LO TS
CP0517491 Compound Info	[2-[7-methyl-3-(pyrrolidin-1-ylmethyl)-2H-indazol-5-yl]-1-pyridin-2-ylethyl] 4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate Show/Hide	C34H39N7O3	1
1	IC50 = 6.8 nM Bioactivity Info	TI LI LO TS
CP0467386 Compound Info	N-[1-(5-bromo-1H-imidazol-2-yl)-2-(7-methyl-1H-indazol-5-yl)ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C27H29BrN8O2	1
1	IC50 = 7.4 nM Bioactivity Info	TI LI LO TS
CP0517282 Compound Info	3-[1-[4-(7-methyl-1H-indazol-5-yl)-3-pyridin-2-ylbutanoyl]piperidin-4-yl]-1,4-dihydroquinazolin-2-one Show/Hide	C30H32N6O2	2
1	IC50 = 8.6 nM Bioactivity Info	TI LI LO TS
2	IC50 = 8.7 nM Bioactivity Info	TI LI LO TS
CP0424040 Compound Info	N-[(2R)-3-(1-benzothiophen-3-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide Show/Hide	C34H42N6O3S	2
1	IC50 = 9 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.55 nM Bioactivity Info	TI LI LO TS
CP0400336 Compound Info	3-[1-[3-(4-ethylpyridin-2-yl)-4-(7-methyl-1H-indazol-5-yl)butanoyl]piperidin-4-yl]-1,4-dihydroquinazolin-2-one Show/Hide	C32H36N6O2	2
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
2	IC50 = 13 nM Bioactivity Info	TI LI LO TS
CP0467253 Compound Info	(2S,5R)-3-(3,3-dimethylbutyl)-2-[2-(4-methylpiperazin-1-yl)phenyl]-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C35H48N6O3S	2
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.9 nM Bioactivity Info	TI LI LO TS
CP0517334 Compound Info	(2R)-2-[(7-methyl-1H-indazol-5-yl)methyl]-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C36H47N7O3	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0428379 Compound Info	3-[1-[4-(7-methyl-1H-indazol-5-yl)-3-(5-methylpyridin-2-yl)butanoyl]piperidin-4-yl]-1,4-dihydroquinazolin-2-one Show/Hide	C31H34N6O2	2
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
2	IC50 = 18 nM Bioactivity Info	TI LI LO TS
CP0428382 Compound Info	N-[2-(7-methyl-1H-indazol-5-yl)-1-(6-phenylpyridin-2-yl)ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C35H35N7O2	2
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
2	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0522527 Compound Info	[2-(7-methyl-1H-indazol-5-yl)-1-pyridin-2-ylethyl] 4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxylate Show/Hide	C30H29N5O3	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0481072 Compound Info	2-(1H-indazol-5-ylmethyl)-4-(2-oxospiro[1H-3,1-benzoxazine-4,4'-piperidine]-1'-yl)-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C34H42N6O4	2
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
2	IC50 = 53 nM Bioactivity Info	TI LI LO TS
CP0517321 Compound Info	2-[(7-methyl-1H-indazol-5-yl)methyl]-4-(2-oxospiro[1H-3,1-benzoxazine-4,4'-piperidine]-1'-yl)-1-piperidin-1-ylbutane-1,4-dione Show/Hide	C30H35N5O4	2
1	IC50 = 19 nM Bioactivity Info	TI LI LO TS
2	IC50 = 34 nM Bioactivity Info	TI LI LO TS
CP0421544 Compound Info	3-(3,3-dimethylbutyl)-2-[2-(4-methylpiperazin-1-yl)phenyl]-5-[2-oxo-2-[4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C36H50N6O3S	2
1	IC50 = 19 nM Bioactivity Info	TI LI LO TS
2	Ki = 2 nM Bioactivity Info	TI LI LO TS
CP0522898 Compound Info	8-fluoro-3-[1-[4-(7-methyl-1H-indazol-5-yl)-3-pyridin-2-ylbutanoyl]piperidin-4-yl]-1,4-dihydroquinazolin-2-one Show/Hide	C30H31FN6O2	2
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
2	IC50 = 35 nM Bioactivity Info	TI LI LO TS
CP0524990 Compound Info	3-[1-[4-(7-methyl-1H-indazol-5-yl)-3-pyridin-2-ylbutanoyl]piperidin-4-yl]-1H-quinolin-2-one Show/Hide	C31H31N5O2	2
1	IC50 = 24 nM Bioactivity Info	TI LI LO TS
2	IC50 = 30 nM Bioactivity Info	TI LI LO TS
CP0527353 Compound Info	2-[2-(7-methyl-1H-indazol-5-yl)-1-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carbonyl]oxyethyl]pyridine-4-carboxylic acid Show/Hide	C30H30N6O5	2
1	IC50 = 28 nM Bioactivity Info	TI LI LO TS
2	IC50 = 30 nM Bioactivity Info	TI LI LO TS
CP0399632 Compound Info	(2S)-2-(4-chloro-2-nitroanilino)-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C33H42ClN7O5	1
1	IC50 = 32 nM Bioactivity Info	TI LI LO TS
CP0395147 Compound Info	3-(3,3-dimethylbutyl)-5-[2-oxo-2-[4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidin-1-yl]ethyl]-2-(2-piperazin-1-ylphenyl)-1,3-thiazolidin-4-one Show/Hide	C35H48N6O3S	2
1	IC50 = 33 nM Bioactivity Info	TI LI LO TS
2	Ki = 1 nM Bioactivity Info	TI LI LO TS
CP0476013 Compound Info	1-(2,4-dichlorophenyl)-3-[(2S)-1,4-dioxo-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butan-2-yl]urea Show/Hide	C34H43Cl2N7O4	1
1	IC50 = 36 nM Bioactivity Info	TI LI LO TS
CP0484611 Compound Info	3-(3,3-dimethylbutyl)-2-[2-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl]-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C36H50N6O4S	2
1	IC50 = 36 nM Bioactivity Info	TI LI LO TS
2	Ki = 8 nM Bioactivity Info	TI LI LO TS
CP0431774 Compound Info	3-(3,3-dimethylbutyl)-2-[2-(4-methylpiperazin-1-yl)phenyl]-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C35H48N6O3S	2
1	IC50 = 40 nM Bioactivity Info	TI LI LO TS
2	Ki = 2 nM Bioactivity Info	TI LI LO TS
CP0372685 Compound Info	4-(2-Oxo-benzooxazol-3-yl)-piperidine-1-carboxylic acid [(S)-1-[(R)-5-amino-1-(4-pyridin-4-yl-piperazine-1-carbonyl)-pentylcarbamoyl]-2-(3,5-dibromo-4-hydroxy-phenyl)-ethyl]-amide Show/Hide	C37H44Br2N8O6	2
1	IC50 = 44 nM Bioactivity Info	TI LI LO TS
2	Kd = 10 nM Bioactivity Info	TI LI LO TS
CP0431772 Compound Info	2-[2-(4-butylpiperazin-1-yl)phenyl]-3-(3,3-dimethylbutyl)-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C38H54N6O3S	2
1	IC50 = 44 nM Bioactivity Info	TI LI LO TS
2	Ki = 3 nM Bioactivity Info	TI LI LO TS
CP0431773 Compound Info	3-(3,3-dimethylbutyl)-2-[2-(4-hydroxypiperidin-1-yl)phenyl]-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C35H47N5O4S	2
1	IC50 = 44 nM Bioactivity Info	TI LI LO TS
2	Ki = 18 nM Bioactivity Info	TI LI LO TS
CP0519804 Compound Info	1-[(2S)-1,4-dioxo-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butan-2-yl]-3-(2-fluorophenyl)urea Show/Hide	C34H44FN7O4	1
1	IC50 = 45 nM Bioactivity Info	TI LI LO TS
CP0399630 Compound Info	(2S)-2-[(6-chloropyrimidin-4-yl)amino]-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C31H41ClN8O3	2
1	IC50 = 46 nM Bioactivity Info	TI LI LO TS
2	IC50 = 98 nM Bioactivity Info	TI LI LO TS
CP0443517 Compound Info	(2S,5S)-2-[2-(4-tert-butylpiperazin-1-yl)-3-fluorophenyl]-3-(3,3-dimethylbutyl)-5-[2-oxo-2-[4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C39H55FN6O3S	2
1	IC50 = 46 nM Bioactivity Info	TI LI LO TS
2	Ki = 1 nM Bioactivity Info	TI LI LO TS
CP0548447 Compound Info	(2S)-2-(1H-indol-5-ylamino)-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C35H45N7O3	2
1	IC50 = 59 nM Bioactivity Info	TI LI LO TS
2	IC50 = 180 nM Bioactivity Info	TI LI LO TS
CP0387858 Compound Info	3-(3,3-dimethylbutyl)-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-(2-piperazin-1-ylphenyl)-1,3-thiazolidin-4-one Show/Hide	C34H46N6O3S	2
1	IC50 = 60 nM Bioactivity Info	TI LI LO TS
2	Ki = 2 nM Bioactivity Info	TI LI LO TS
CP0433439 Compound Info	3-(3,3-dimethylbutyl)-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-(2-pyrazol-1-ylphenyl)-1,3-thiazolidin-4-one Show/Hide	C33H40N6O3S	2
1	IC50 = 62 nM Bioactivity Info	TI LI LO TS
2	Ki = 40 nM Bioactivity Info	TI LI LO TS
CP0433438 Compound Info	3-(3,3-dimethylbutyl)-2-[2-fluoro-6-(4-methylpiperazin-1-yl)phenyl]-5-[2-oxo-2-[4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C36H49FN6O3S	2
1	IC50 = 65 nM Bioactivity Info	TI LI LO TS
2	Ki = 1 nM Bioactivity Info	TI LI LO TS
CP0395146 Compound Info	3-(3,3-dimethylbutyl)-2-[5-fluoro-2-(4-methylpiperazin-1-yl)phenyl]-5-[2-oxo-2-[4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C36H49FN6O3S	2
1	IC50 = 72 nM Bioactivity Info	TI LI LO TS
2	Ki = 14 nM Bioactivity Info	TI LI LO TS
CP0476014 Compound Info	(2S)-2-[(7-methyl-2H-triazolo[4,5-d]pyrimidin-5-yl)amino]-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C32H43N11O3	2
1	IC50 = 73 nM Bioactivity Info	TI LI LO TS
2	IC50 = 120 nM Bioactivity Info	TI LI LO TS
CP0430621 Compound Info	(2S)-2-[(4-amino-6-methyl-5-nitropyrimidin-2-yl)amino]-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C32H44N10O5	1
1	IC50 = 80 nM Bioactivity Info	TI LI LO TS
CP0467321 Compound Info	3-(3,3-dimethylbutyl)-2-[4-fluoro-2-(4-methylpiperazin-1-yl)phenyl]-5-[2-oxo-2-[4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C36H49FN6O3S	2
1	IC50 = 84 nM Bioactivity Info	TI LI LO TS
2	Ki = 14 nM Bioactivity Info	TI LI LO TS
CP0443685 Compound Info	3-(3,3-dimethylbutyl)-2-(2-imidazol-1-ylphenyl)-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C33H40N6O3S	2
1	IC50 = 86 nM Bioactivity Info	TI LI LO TS
2	Ki = 7 nM Bioactivity Info	TI LI LO TS
CP0519810 Compound Info	1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-2-(1H-indazol-5-ylmethyl)-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]butane-1,4-dione Show/Hide	C32H38N6O5	2
1	IC50 = 87 nM Bioactivity Info	TI LI LO TS
2	IC50 = 320 nM Bioactivity Info	TI LI LO TS
CP0387857 Compound Info	3-(3,3-dimethylbutyl)-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-(2-pyridin-3-ylphenyl)-1,3-thiazolidin-4-one Show/Hide	C35H41N5O3S	2
1	IC50 = 88 nM Bioactivity Info	TI LI LO TS
2	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0430620 Compound Info	1-(2,3-dichlorophenyl)-3-[(2S)-1,4-dioxo-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butan-2-yl]urea Show/Hide	C34H43Cl2N7O4	1
1	IC50 = 97 nM Bioactivity Info	TI LI LO TS
CP0482429 Compound Info	N-[1-(1H-imidazol-2-yl)-2-(7-methyl-1H-indazol-5-yl)ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C27H30N8O2	1
1	IC50 = 97 nM Bioactivity Info	TI LI LO TS
CP0519396 Compound Info	(2R,5R)-3-(3,3-dimethylbutyl)-2-[2-(4-methylpiperazin-1-yl)phenyl]-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C35H48N6O3S	2
1	IC50 = 98 nM Bioactivity Info	TI LI LO TS
2	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0519806 Compound Info	(2S)-2-[(6-chloro-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino]-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C32H41ClN10O3	2
1	IC50 = 99 nM Bioactivity Info	TI LI LO TS
2	IC50 = 250 nM Bioactivity Info	TI LI LO TS
CP0407429 Compound Info	3-(3,3-dimethylbutyl)-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-(2-pyridin-4-ylphenyl)-1,3-thiazolidin-4-one Show/Hide	C35H41N5O3S	2
1	IC50 = 99 nM Bioactivity Info	TI LI LO TS
2	Ki = 20 nM Bioactivity Info	TI LI LO TS
CP0519808 Compound Info	1-(2-chlorophenyl)-3-[(2S)-1,4-dioxo-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butan-2-yl]urea Show/Hide	C34H44ClN7O4	1
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
CP0558040 Compound Info	(2S)-2-[(4-bromonaphthalen-1-yl)amino]-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C37H45BrN6O3	1
1	IC50 = 120 nM Bioactivity Info	TI LI LO TS
CP0482494 Compound Info	N-[1-(5-methyl-1H-imidazol-2-yl)-2-(7-methyl-1H-indazol-5-yl)ethyl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C28H32N8O2	1
1	IC50 = 120 nM Bioactivity Info	TI LI LO TS
CP0399628 Compound Info	(2S)-2-(1H-indazol-5-ylmethylamino)-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C35H46N8O3	2
1	IC50 = 130 nM Bioactivity Info	TI LI LO TS
2	IC50 = 300 nM Bioactivity Info	TI LI LO TS
CP0467255 Compound Info	3-(3,3-dimethylbutyl)-2-(2-morpholin-4-ylphenyl)-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C34H45N5O4S	2
1	IC50 = 160 nM Bioactivity Info	TI LI LO TS
2	Ki = 52 nM Bioactivity Info	TI LI LO TS
CP0499038 Compound Info	(2S)-2-(1H-indazol-5-ylamino)-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C34H44N8O3	2
1	IC50 = 170 nM Bioactivity Info	TI LI LO TS
2	IC50 = 230 nM Bioactivity Info	TI LI LO TS
CP0524957 Compound Info	N-[(2R)-3-(1-benzothiophen-3-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-2-oxospiro[1H-indole-3,4'-piperidine]-1'-carboxamide Show/Hide	C34H41N5O3S	1
1	IC50 = 170 nM Bioactivity Info	TI LI LO TS
CP0443520 Compound Info	2-(2,6-difluorophenyl)-3-(3,3-dimethylbutyl)-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C30H36F2N4O3S	2
1	IC50 = 170 nM Bioactivity Info	TI LI LO TS
2	Ki = 59 nM Bioactivity Info	TI LI LO TS
CP0525357 Compound Info	3-(3,3-dimethylbutyl)-2-(2-fluorophenyl)-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C30H37FN4O3S	2
1	IC50 = 180 nM Bioactivity Info	TI LI LO TS
2	Ki = 54 nM Bioactivity Info	TI LI LO TS
CP0433440 Compound Info	2-(2,4-difluorophenyl)-3-(3,3-dimethylbutyl)-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C30H36F2N4O3S	2
1	IC50 = 190 nM Bioactivity Info	TI LI LO TS
2	Ki = 30 nM Bioactivity Info	TI LI LO TS
CP0378931 Compound Info	(S)-N-[(R)-5-Amino-1-(4-pyridin-4-yl-piperazine-1-carbonyl)-pentyl]-3-(3,5-dibromo-4-hydroxy-phenyl)-2-{3-[2-(3-methoxy-phenyl)-ethyl]-ureido}-propionamide Show/Hide	C34H43Br2N7O5	2
1	IC50 = 200 nM Bioactivity Info	TI LI LO TS
2	Kd = 125.89 nM Bioactivity Info	TI LI LO TS
CP0507372 Compound Info	N-[(2R)-3-(1-benzothiophen-3-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-oxo-2-pyridin-3-yl-1,3,8-triazaspiro[4.5]dec-1-ene-8-carboxamide Show/Hide	C34H41N7O3S	1
1	IC50 = 210 nM Bioactivity Info	TI LI LO TS
CP0387859 Compound Info	2-(2,3-difluorophenyl)-3-(3,3-dimethylbutyl)-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C30H36F2N4O3S	2
1	IC50 = 210 nM Bioactivity Info	TI LI LO TS
2	Ki = 118 nM Bioactivity Info	TI LI LO TS
CP0550505 Compound Info	(2S)-2-(naphthalen-1-ylamino)-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C37H46N6O3	1
1	IC50 = 220 nM Bioactivity Info	TI LI LO TS
CP0505627 Compound Info	4-(2-Methoxy-phenyl)-piperazine-1-carboxylic acid [(S)-1-[(R)-5-amino-1-(4-pyridin-4-yl-piperazine-1-carbonyl)-pentylcarbamoyl]-2-(3,5-dibromo-4-hydroxy-phenyl)-ethyl]-amide Show/Hide	C36H46Br2N8O5	1
1	IC50 = 226 nM Bioactivity Info	TI LI LO TS
CP0448612 Compound Info	4-(2-Methoxy-phenyl)-piperidine-1-carboxylic acid [(S)-1-[(R)-5-amino-1-(4-pyridin-4-yl-piperazine-1-carbonyl)-pentylcarbamoyl]-2-(3,5-dibromo-4-hydroxy-phenyl)-ethyl]-amide Show/Hide	C37H47Br2N7O5	1
1	IC50 = 250 nM Bioactivity Info	TI LI LO TS
CP0443689 Compound Info	3-(2,2-dimethylpropyl)-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-phenyl-1,3-thiazolidin-4-one Show/Hide	C29H36N4O3S	2
1	IC50 = 250 nM Bioactivity Info	TI LI LO TS
2	Ki = 9 nM Bioactivity Info	TI LI LO TS
CP0517333 Compound Info	phenyl N-[(2S)-1,4-dioxo-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butan-2-yl]carbamate Show/Hide	C34H44N6O5	1
1	IC50 = 280 nM Bioactivity Info	TI LI LO TS
CP0443696 Compound Info	3-butyl-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-phenyl-1,3-thiazolidin-4-one Show/Hide	C28H34N4O3S	2
1	IC50 = 320 nM Bioactivity Info	TI LI LO TS
2	Ki = 64 nM Bioactivity Info	TI LI LO TS
CP0544582 Compound Info	N-[(2R)-3-(1-benzothiophen-3-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-8-carboxamide Show/Hide	C35H44N6O3S	1
1	IC50 = 330 nM Bioactivity Info	TI LI LO TS
CP0431781 Compound Info	3-(3-methylbutyl)-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-phenyl-1,3-thiazolidin-4-one Show/Hide	C29H36N4O3S	2
1	IC50 = 370 nM Bioactivity Info	TI LI LO TS
2	Ki = 32 nM Bioactivity Info	TI LI LO TS
CP0525359 Compound Info	3-(2-methylpropyl)-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-phenyl-1,3-thiazolidin-4-one Show/Hide	C28H34N4O3S	2
1	IC50 = 370 nM Bioactivity Info	TI LI LO TS
2	Ki = 32 nM Bioactivity Info	TI LI LO TS
CP0524779 Compound Info	(2S)-2-(1H-indol-5-ylmethylamino)-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C36H47N7O3	1
1	IC50 = 380 nM Bioactivity Info	TI LI LO TS
CP0399629 Compound Info	N-[(2S)-1,4-dioxo-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butan-2-yl]-3,4-difluorobenzamide Show/Hide	C34H42F2N6O4	1
1	IC50 = 430 nM Bioactivity Info	TI LI LO TS
CP0549659 Compound Info	1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-2-(1H-indazol-5-ylmethyl)-4-(2-oxospiro[1H-3,1-benzoxazine-4,4'-piperidine]-1'-yl)butane-1,4-dione Show/Hide	C31H35N5O6	1
1	IC50 = 460 nM Bioactivity Info	TI LI LO TS
CP0443691 Compound Info	3-(oxolan-2-ylmethyl)-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-phenyl-1,3-thiazolidin-4-one Show/Hide	C29H34N4O4S	2
1	IC50 = 520 nM Bioactivity Info	TI LI LO TS
2	Ki = 68 nM Bioactivity Info	TI LI LO TS
CP0524780 Compound Info	tert-butyl N-[(2S)-1,4-dioxo-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butan-2-yl]carbamate Show/Hide	C32H48N6O5	1
1	IC50 = 590 nM Bioactivity Info	TI LI LO TS
CP0558039 Compound Info	(2S)-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)-2-(pyridin-2-ylmethylamino)butane-1,4-dione Show/Hide	C33H45N7O3	1
1	IC50 = 700 nM Bioactivity Info	TI LI LO TS
CP0443521 Compound Info	3-cyclohexyl-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-phenyl-1,3-thiazolidin-4-one Show/Hide	C30H36N4O3S	2
1	IC50 = 710 nM Bioactivity Info	TI LI LO TS
2	Ki = 88 nM Bioactivity Info	TI LI LO TS
CP0467027 Compound Info	N-[(3,5-dibromo-4-hydroxyphenyl)methyl]-N-(3-methylbutyl)-4-oxo-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]butanamide Show/Hide	C29H36Br2N4O4	2
1	IC50 = 740 nM Bioactivity Info	TI LI LO TS
2	Ki = 282 nM Bioactivity Info	TI LI LO TS
CP0443687 Compound Info	3-[(4-fluorophenyl)methyl]-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-phenyl-1,3-thiazolidin-4-one Show/Hide	C31H31FN4O3S	2
1	IC50 = 750 nM Bioactivity Info	TI LI LO TS
2	Ki = 56 nM Bioactivity Info	TI LI LO TS
CP0467256 Compound Info	5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-phenyl-3-(pyridin-3-ylmethyl)-1,3-thiazolidin-4-one Show/Hide	C30H31N5O3S	2
1	IC50 = 800 nM Bioactivity Info	TI LI LO TS
2	Ki = 260 nM Bioactivity Info	TI LI LO TS
CP0484610 Compound Info	3-(cyclopropylmethyl)-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-phenyl-1,3-thiazolidin-4-one Show/Hide	C28H32N4O3S	2
1	IC50 = 840 nM Bioactivity Info	TI LI LO TS
2	Ki = 45 nM Bioactivity Info	TI LI LO TS
CP0492353 Compound Info	N-[(2R)-3-(1-benzothiophen-3-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-1-methyl-4-oxospiro[3H-quinazoline-2,4'-piperidine]-1'-carboxamide Show/Hide	C35H44N6O3S	1
1	IC50 = 860 nM Bioactivity Info	TI LI LO TS
CP0430622 Compound Info	(2S)-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)-2-(quinolin-5-ylamino)butane-1,4-dione Show/Hide	C36H45N7O3	1
1	IC50 = 890 nM Bioactivity Info	TI LI LO TS
CP0525364 Compound Info	5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-phenyl-3-(1-phenylethyl)-1,3-thiazolidin-4-one Show/Hide	C32H34N4O3S	2
1	IC50 = 940 nM Bioactivity Info	TI LI LO TS
2	Ki = 297 nM Bioactivity Info	TI LI LO TS
CP0466977 Compound Info	(S)-N-[(R)-5-Amino-1-(4-pyridin-4-yl-piperazine-1-carbonyl)-pentyl]-3-(3,5-dibromo-4-hydroxy-phenyl)-2-{3-[2-(2-methoxy-phenyl)-ethyl]-ureido}-propionamide Show/Hide	C34H43Br2N7O5	1
1	IC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0407432 Compound Info	3-(2-methoxyethyl)-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-phenyl-1,3-thiazolidin-4-one Show/Hide	C27H32N4O4S	2
1	IC50 = 1220 nM Bioactivity Info	TI LI LO TS
2	Ki = 124 nM Bioactivity Info	TI LI LO TS
CP0407430 Compound Info	5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-phenyl-3-(2-pyridin-2-ylethyl)-1,3-thiazolidin-4-one Show/Hide	C31H33N5O3S	2
1	IC50 = 1370 nM Bioactivity Info	TI LI LO TS
2	Ki = 202 nM Bioactivity Info	TI LI LO TS
CP0549362 Compound Info	(2S)-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)-2-(pyrimidin-4-ylamino)butane-1,4-dione Show/Hide	C31H42N8O3	1
1	IC50 = 1400 nM Bioactivity Info	TI LI LO TS
CP0524958 Compound Info	N-[(2R)-3-(1-benzothiophen-3-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-oxo-2-pyridin-4-yl-1,3,8-triazaspiro[4.5]dec-1-ene-8-carboxamide Show/Hide	C34H41N7O3S	1
1	IC50 = 1400 nM Bioactivity Info	TI LI LO TS
CP0380902 Compound Info	5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-phenyl-3-propan-2-yl-1,3-thiazolidin-4-one Show/Hide	C27H32N4O3S	2
1	IC50 = 1500 nM Bioactivity Info	TI LI LO TS
2	Ki = 115 nM Bioactivity Info	TI LI LO TS
CP0387861 Compound Info	5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2,3-diphenyl-1,3-thiazolidin-4-one Show/Hide	C30H30N4O3S	2
1	IC50 = 2940 nM Bioactivity Info	TI LI LO TS
2	Ki = 806 nM Bioactivity Info	TI LI LO TS
CP0443698 Compound Info	3-methyl-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-phenyl-1,3-thiazolidin-4-one Show/Hide	C25H28N4O3S	2
1	IC50 = 4470 nM Bioactivity Info	TI LI LO TS
2	Ki = 203 nM Bioactivity Info	TI LI LO TS
CP0517332 Compound Info	(2S)-2-[(4-hydroxycyclohexyl)amino]-4-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione Show/Hide	C33H50N6O4	1
1	IC50 = 4500 nM Bioactivity Info	TI LI LO TS
CP0387870 Compound Info	5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-phenyl-3-(2,2,2-trifluoroethyl)-1,3-thiazolidin-4-one Show/Hide	C26H27F3N4O3S	2
1	IC50 = 4540 nM Bioactivity Info	TI LI LO TS
2	Ki = 763 nM Bioactivity Info	TI LI LO TS
CP0443692 Compound Info	3-[2-(diethylamino)ethyl]-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-phenyl-1,3-thiazolidin-4-one Show/Hide	C30H39N5O3S	2
1	IC50 = 4880 nM Bioactivity Info	TI LI LO TS
2	Ki = 303 nM Bioactivity Info	TI LI LO TS
CP0433441 Compound Info	3-cyclopropyl-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-phenyl-1,3-thiazolidin-4-one Show/Hide	C27H30N4O3S	2
1	IC50 = 5150 nM Bioactivity Info	TI LI LO TS
2	Ki = 865 nM Bioactivity Info	TI LI LO TS
CP0443693 Compound Info	3-tert-butyl-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-2-phenyl-1,3-thiazolidin-4-one Show/Hide	C28H34N4O3S	2
1	IC50 = 7600 nM Bioactivity Info	TI LI LO TS
2	Ki = 1880 nM Bioactivity Info	TI LI LO TS
CP0428997 Compound Info	N-[(2R)-3-(1-benzothiophen-3-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-2-cyclohexyl-4-oxo-1,3,8-triazaspiro[4.5]dec-1-ene-8-carboxamide Show/Hide	C35H48N6O3S	1
1	IC50 = 8500 nM Bioactivity Info	TI LI LO TS
CP0436217 Compound Info	N-[(2S)-3-(4-amino-3,5-dibromophenyl)-1-[[(2R)-6-amino-1-oxo-1-(4-pyridin-4-ylpiperazin-1-yl)hexan-2-yl]amino]-1-oxopropan-2-yl]-4-phenylbutanamide Show/Hide	C34H43Br2N7O3	1
1	IC50 = 10300 nM Bioactivity Info	TI LI LO TS
CP0436218 Compound Info	(R)-6-Amino-2-((S)-3-(3,5-dibromo-4-hydroxy-phenyl)-2-{3-[2-(2-methoxy-phenyl)-ethyl]-ureido}-propionylamino)-hexanoic acid phenethyl-amide Show/Hide	C33H41Br2N5O5	1
1	IC50 = 13000 nM Bioactivity Info	TI LI LO TS
CP0395150 Compound Info	(2S,5S)-3-(3,3-dimethylbutyl)-2-[2-(4-methylpiperazin-1-yl)phenyl]-5-[2-oxo-2-[4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidin-1-yl]ethyl]-1,3-thiazolidin-4-one Show/Hide	C35H48N6O3S	2
1	IC50 = 13900 nM Bioactivity Info	TI LI LO TS
2	Ki = 1800 nM Bioactivity Info	TI LI LO TS
CP0486663 Compound Info	(R)-6-Amino-2-[(S)-3-(3,5-dibromo-4-hydroxy-phenyl)-2-(4-phenyl-butyrylamino)-propionylamino]-hexanoic acid phenethyl-amide Show/Hide	C33H40Br2N4O4	1
1	IC50 = 17000 nM Bioactivity Info	TI LI LO TS
CP0431289 Compound Info	(R)-6-Amino-2-[(S)-3-(4-amino-3,5-dibromo-phenyl)-2-(4-phenyl-butyrylamino)-propionylamino]-hexanoic acid phenethyl-amide Show/Hide	C33H41Br2N5O3	1
1	IC50 = 40000 nM Bioactivity Info	TI LI LO TS
CP0428061 Compound Info	(R)-6-Amino-2-[(S)-3-(4-amino-3,5-dibromo-phenyl)-2-(4-phenyl-butyrylamino)-propionylamino]-hexanoic acid phenylamide Show/Hide	C31H37Br2N5O3	1
1	IC50 = 50000 nM Bioactivity Info	TI LI LO TS
CP0914646 Compound Info	(S)-4-Chloro-7-{2-oxo-2-[4-(2-oxo-1,2,4,5-tetrahydro-benzo[d][1,3]diazepin-3-yl)-piperidin-1-yl]-ethyl}-9-(2,2,2-trifluoro-ethyl)-1,3,6,7,9,10-hexahydro-1,3,9-triaza-cyclohepta[e]indene-2,8-dione Show/Hide	C29H30ClF3N6O4	1
1	Ki = 0.019 nM Bioactivity Info	TI LI LO TS
CP0962458 Compound Info	(S)-4-Chloro-7-{2-oxo-2-[4-(2-oxo-2,3-dihydro-imidazo[4,5-b]pyridin-1-yl)-piperidin-1-yl]-ethyl}-1,9-bis-(2,2,2-trifluoro-ethyl)-1,3,6,7,9,10-hexahydro-1,3,9-triaza-cyclohepta[e]indene-2,8-dione Show/Hide	C28H26ClF6N7O4	1
1	Ki = 0.026 nM Bioactivity Info	TI LI LO TS
CP0955001 Compound Info	(S)-4-Chloro-1-methyl-7-{2-oxo-2-[4-(6-oxo-5,6,8,9-tetrahydro-1,5,7-triaza-benzocyclohepten-7-yl)-piperidin-1-yl]-ethyl}-9-(2,2,2-trifluoro-ethyl)-1,3,6,7,9,10-hexahydro-1,3,9-triaza-cyclohepta[e]indene-2,8-dione Show/Hide	C29H31ClF3N7O4	1
1	Ki = 0.043 nM Bioactivity Info	TI LI LO TS
CP0697885 Compound Info	(S)-4-chloro-7-(2-oxo-2-(4-(2-oxo-4,5-dihydro-1H-benzo[d][1,3]diazepin-3(2H)-yl)piperidin-1-yl)ethyl)-9-(2,2,2-trifluoroethyl)-6,7,9,10-tetrahydroazepino[3,4-e]indazol-8(3H)-one Show/Hide	C29H30ClF3N6O3	1
1	Ki = 0.046 nM Bioactivity Info	TI LI LO TS
CP0911094 Compound Info	(S)-4-Chloro-8-oxo-7-{2-oxo-2-[4-(2-oxo-2,3-dihydro-imidazo[4,5-b]pyridin-1-yl)-piperidin-1-yl]-ethyl}-9-(2,2,2-trifluoro-ethyl)-3,6,7,8,9,10-hexahydro-3,9-diaza-cyclohepta[e]indene-1-carbonitrile Show/Hide	C28H25ClF3N7O3	1
1	Ki = 0.06 nM Bioactivity Info	TI LI LO TS
CP0959145 Compound Info	(S)-4-Chloro-8-oxo-7-{2-oxo-2-[4-(2-oxo-1,2,4,5-tetrahydro-benzo[d][1,3]diazepin-3-yl)-piperidin-1-yl]-ethyl}-9-(2,2,2-trifluoro-ethyl)-3,6,7,8,9,10-hexahydro-3,9-diaza-cyclohepta[e]indene-1-carbonitrile Show/Hide	C31H30ClF3N6O3	1
1	Ki = 0.06 nM Bioactivity Info	TI LI LO TS
CP0376813 Compound Info	[(5S,6S,9R)-5-azido-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl] 4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate Show/Hide	C28H26F2N8O3	1
1	Ki = 0.066 nM Bioactivity Info	TI LI LO TS
CP0567565 Compound Info	(4S)-7-chloro-10,10-difluoro-4-[2-oxo-2-[4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidin-1-yl]ethyl]-2-(2,2,2-trifluoroethyl)-1,4,5,8-tetrahydropyrrolo[2,3-i][2]benzazepine-3,9-dione Show/Hide	C30H29ClF5N5O4	1
1	Ki = 0.069 nM Bioactivity Info	TI LI LO TS
CP0452710 Compound Info	[(5S,6S,9R)-6-(2,3-difluorophenyl)-5-hydroxy-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl] 4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate Show/Hide	C28H27F2N5O4	1
1	Ki = 0.081 nM Bioactivity Info	TI LI LO TS
CP0959142 Compound Info	(S)-4-Chloro-7-{2-oxo-2-[4-(2-oxo-1,2,4,5-tetrahydro-benzo[d][1,3]diazepin-3-yl)-piperidin-1-yl]-ethyl}-9-(2,2,2-trifluoro-ethyl)-6,7,9,10-tetrahydro-3H-1-oxa-3,9-diaza-cyclohepta[e]indene-2,8-dione Show/Hide	C29H29ClF3N5O5	1
1	Ki = 0.12 nM Bioactivity Info	TI LI LO TS
CP0959146 Compound Info	(S)-4-Chloro-1,1-difluoro-7-{2-oxo-2-[4-(2-oxo-2,3-dihydro-imidazo[4,5-b]pyridin-1-yl)-piperidin-1-yl]-ethyl}-9-(2,2,2-trifluoro-ethyl)-1,3,6,7,9,10-hexahydro-3,9-diaza-cyclohepta[e]indene-2,8-dione Show/Hide	C27H24ClF5N6O4	1
1	Ki = 0.13 nM Bioactivity Info	TI LI LO TS
CP0962459 Compound Info	(S)-4-Chloro-7-{2-oxo-2-[4-(2-oxo-1,2,4,5-tetrahydro-benzo[d][1,3]diazepin-3-yl)-piperidin-1-yl]-ethyl}-9-(2,2,2-trifluoro-ethyl)-6,7,9,10-tetrahydro-3H-1,3,9-triaza-cyclohepta[e]inden-8-one Show/Hide	C29H30ClF3N6O3	1
1	Ki = 0.17 nM Bioactivity Info	TI LI LO TS
CP0428994 Compound Info	4-(2-oxo-1,4-dihydroquinazolin-3-yl)-N-[(2R)-1-oxo-3-(2-oxo-3H-1,3-benzoxazol-6-yl)-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide Show/Hide	C34H43N7O5	1
1	Ki = 0.27 nM Bioactivity Info	TI LI LO TS
CP0914647 Compound Info	(S)-4-Chloro-8-oxo-7-{2-oxo-2-[4-(2-oxo-2,3-dihydro-imidazo[4,5-b]pyridin-1-yl)-piperidin-1-yl]-ethyl}-9-(2,2,2-trifluoro-ethyl)-3,6,7,8,9,10-hexahydro-3,9-diaza-cyclohepta[e]indene-1-carboxylic acid amide Show/Hide	C28H27ClF3N7O4	1
1	Ki = 0.4 nM Bioactivity Info	TI LI LO TS
CP0952877 Compound Info	(S)-4-Chloro-7-{2-oxo-2-[4-(2-oxo-1,2,4,5-tetrahydro-benzo[d][1,3]diazepin-3-yl)-piperidin-1-yl]-ethyl}-9-(2,2,2-trifluoro-ethyl)-6,7,9,10-tetrahydro-3H-1,2,3,9-tetraaza-cyclohepta[e]inden-8-one Show/Hide	C28H29ClF3N7O3	1
1	Ki = 0.44 nM Bioactivity Info	TI LI LO TS
CP0544663 Compound Info	N-[(2R)-3-(2H-benzotriazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C33H43N9O3	1
1	Ki = 0.55 nM Bioactivity Info	TI LI LO TS
CP0415707 Compound Info	N-[(2R)-3-(3,5-dibromo-4-hydroxyphenyl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide Show/Hide	C32H40Br2N6O4	1
1	Ki = 0.65 nM Bioactivity Info	TI LI LO TS
CP0428995 Compound Info	4-(2-oxo-1,4-dihydroquinazolin-3-yl)-N-[(2R)-1-oxo-3-(2-oxo-1,3-dihydroindol-5-yl)-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide Show/Hide	C35H45N7O4	1
1	Ki = 0.65 nM Bioactivity Info	TI LI LO TS
CP0523294 Compound Info	[(5S,6R,9R)-6-(2,3-difluorophenyl)-5-hydroxy-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl] 4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate Show/Hide	C28H27F2N5O4	1
1	Ki = 0.67 nM Bioactivity Info	TI LI LO TS
CP0963890 Compound Info	(S)-4-Chloro-7-{2-oxo-2-[4-(2-oxo-1,2,4,5-tetrahydro-benzo[d][1,3]diazepin-3-yl)-piperidin-1-yl]-ethyl}-9-(2,2,2-trifluoro-ethyl)-6,7,9,10-tetrahydro-3H-3,9-diaza-cyclohepta[e]inden-8-one Show/Hide	C30H31ClF3N5O3	1
1	Ki = 0.85 nM Bioactivity Info	TI LI LO TS
CP0513141 Compound Info	N-[(2R)-3-(4-hydroxyphenyl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide Show/Hide	C32H42N6O4	1
1	Ki = 2.5 nM Bioactivity Info	TI LI LO TS
CP0481680 Compound Info	[(5R,6S,9R)-6-(2,3-difluorophenyl)-5-hydroxy-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl] 4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate Show/Hide	C28H27F2N5O4	1
1	Ki = 4.3 nM Bioactivity Info	TI LI LO TS
CP0410318 Compound Info	N-[(2R)-3-naphthalen-1-yl-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide Show/Hide	C36H44N6O3	1
1	Ki = 7.2 nM Bioactivity Info	TI LI LO TS
CP0557853 Compound Info	N-[(2R)-3-(1-methylindol-3-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide Show/Hide	C35H45N7O3	1
1	Ki = 16 nM Bioactivity Info	TI LI LO TS
CP0415709 Compound Info	N-[(2R)-3-(2-methyl-3H-benzimidazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C35H46N8O3	1
1	Ki = 28 nM Bioactivity Info	TI LI LO TS
CP0492362 Compound Info	N-[3-(1H-indol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide Show/Hide	C34H43N7O3	1
1	Ki = 32 nM Bioactivity Info	TI LI LO TS
CP0523540 Compound Info	N-[3-(1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide Show/Hide	C33H42N8O3	1
1	Ki = 68 nM Bioactivity Info	TI LI LO TS
CP0513143 Compound Info	N-[(2R)-3-(1H-indol-3-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide Show/Hide	C34H43N7O3	1
1	Ki = 84 nM Bioactivity Info	TI LI LO TS
CP0428993 Compound Info	N-[(2R)-3-naphthalen-2-yl-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide Show/Hide	C36H44N6O3	1
1	Ki = 230 nM Bioactivity Info	TI LI LO TS
CP0507371 Compound Info	N-[(2S)-3-(1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C34H44N8O3	1
1	Ki = 250 nM Bioactivity Info	TI LI LO TS
CP0513142 Compound Info	4-(2-oxo-3H-benzimidazol-1-yl)-N-[(2R)-1-oxo-3-(4-phenylphenyl)-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide Show/Hide	C38H46N6O3	1
1	Ki = 250 nM Bioactivity Info	TI LI LO TS
CP0416212 Compound Info	4-(2-oxo-3H-benzimidazol-1-yl)-N-[(2R)-1-oxo-3-phenyl-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide Show/Hide	C32H42N6O3	1
1	Ki = 300 nM Bioactivity Info	TI LI LO TS
CP0507333 Compound Info	N-[(2R)-3-(4-aminophenyl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide Show/Hide	C32H43N7O3	1
1	Ki = 750 nM Bioactivity Info	TI LI LO TS
CP0428992 Compound Info	N-[(2R)-3-(4-methoxyphenyl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide Show/Hide	C33H44N6O4	1
1	Ki = 1400 nM Bioactivity Info	TI LI LO TS
CP0410317 Compound Info	N-[(2R)-3-(4-acetamidophenyl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide Show/Hide	C34H45N7O4	1
1	Ki = 1900 nM Bioactivity Info	TI LI LO TS
CP0544662 Compound Info	N-[(2R)-4-(4-hydroxyphenyl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)butan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide Show/Hide	C33H44N6O4	1
1	Ki = 2100 nM Bioactivity Info	TI LI LO TS
CP0424006 Compound Info	N-[(2R)-4-methyl-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)pentan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide Show/Hide	C29H44N6O3	1
1	Ki = 2400 nM Bioactivity Info	TI LI LO TS
CP0398657 Compound Info	4-(2-oxo-3H-benzimidazol-1-yl)-N-[(1R)-2-oxo-1-phenyl-2-(4-piperidin-1-ylpiperidin-1-yl)ethyl]piperidine-1-carboxamide Show/Hide	C31H40N6O3	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0398661 Compound Info	(4R)-5-oxo-4-[[4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carbonyl]amino]-5-(4-piperidin-1-ylpiperidin-1-yl)pentanoic acid Show/Hide	C28H40N6O5	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0415708 Compound Info	N-[(2R)-5-amino-1,5-dioxo-1-(4-piperidin-1-ylpiperidin-1-yl)pentan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide Show/Hide	C28H41N7O4	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0524956 Compound Info	4-(2-oxo-3H-benzimidazol-1-yl)-N-[(2R)-1-oxo-4-phenyl-1-(4-piperidin-1-ylpiperidin-1-yl)butan-2-yl]piperidine-1-carboxamide Show/Hide	C33H44N6O3	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS
CP0557852 Compound Info	N-[(2S)-3-(3,5-dibromo-4-hydroxyphenyl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxamide Show/Hide	C32H40Br2N6O4	1
1	Ki > 1000 nM Bioactivity Info	TI LI LO TS