General Information of the Protein
| Protein ID |
PT04285
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| Protein Name |
Calcitonin gene-related peptide 1
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| Secondarily Protein Name |
Alpha-type CGRP
Calcitonin gene-related peptide I
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| Gene Name |
CALCA
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| Secondarily Gene Name |
CALC1
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| Sequence |
MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQMKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFGRRRRDLQA
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| Organism |
Homo sapiens, Human
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| Protein Classification |
Secreted protein
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| Function |
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP.
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| Uniprot ID |
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| Ensembl ID | |||||
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| Subcellular Location |
Secreted
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Map of Molecular Bioactivity Related to the Protein
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Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000006 , HEK293
Cell Line ID: CL000074 , SK-N-MC
Clinical Information about the Protein
Target 1 ( Calcitonin gene-related peptide 1 (CALCA) )
| Target Type | Clinical trial Target | ||||
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