Brief Information of the Compound and Protein
Compound Name
4-bromo-N-[(3,5-difluorophenyl)methyl]-6-(1,1-dioxothiazinan-2-yl)-3-hydroxypyridine-2-carboxamide
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PubChem ID
CID: 9847811
SID: 14809862
Canonical SMILES
Oc1c(Br)cc(nc1C(=O)NCc1cc(F)cc(F)c1)N1CCCCS1(=O)=O
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Compound Formula C17H16BrF2N3O4S
Compound Structure
Protein Name
Calcitonin gene-related peptide 1
Protein Classification
Secreted protein
Uniprot ID
P06881
Gene Name
CALCA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 7500 nM
   TI
   LI
   LO
   TS
CL000074 SK-N-MC Homo sapiens (Human)  4
1
IC50 = 2700 nM
   TI
   LI
   LO
   TS
2
Ki = 2700 nM
   TI
   LI
   LO
   TS
3
Ki = 3300 nM
   TI
   LI
   LO
   TS
4
Ki > 100000 nM
   TI
   LI
   LO
   TS