All Bioactivity

Brief Information of the Cell Line and Protein

Cell Line ID: CL000074 , SK-N-MC

Cell Line Info

Synonyms	SKNMC SK-NM-C SK-NMC
Category	Cancer cell line
Organism	Homo sapiens (Human)
Cellosaurus ID	CVCL_0530

Protein ID: PT04285 , Calcitonin gene-related peptide 1

Protein Info

Gene Name	CALCA
Organism	Homo sapiens, Human
Protein Classification	Secreted protein
Uniprot ID	P06881

Table of Molecular Bioactivities Related to the Cell Line and Protein

Cell Line ID: CL000074

Cell Line Info

Protein ID: PT04285

Protein Info

Compound ID	Compound Name	Compound Formula
CP0467359 Compound Info	ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-amide Show/Hide	C163H267N51O49S2	1
1	EC50 = 0.05 nM Bioactivity Info	TI LI LO TS
CP0458714 Compound Info	4-(3-cyanonaphthalen-2-yl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide Show/Hide	C38H45N7O2	1
1	IC50 = 0.11 nM Bioactivity Info	TI LI LO TS
CP0007084 Compound Info	Ac-WVTHRLAGLLSRSGGVVRKNFVPTDVGPFAF-NH2 Show/Hide	C159H246N46O39	2
1	IC50 = 0.2 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.06 nM Bioactivity Info	TI LI LO TS
CP0102191 Compound Info	4-(3-chloronaphthalen-2-yl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide Show/Hide	C37H45ClN6O2	1
1	IC50 = 0.23 nM Bioactivity Info	TI LI LO TS
CP0507949 Compound Info	Ac-WVTHQLAGLLSQSGGVVRKNFVPTDVGPFAF-NH2 Show/Hide	C157H238N42O41	1
1	IC50 = 0.53 nM Bioactivity Info	TI LI LO TS
CP0467355 Compound Info	Ac-WVTH[Cit]LAGLLSRSGGVVRKNFVPTDVGPFAF-NH2 Show/Hide	C159H245N45O40	1
1	IC50 = 0.57 nM Bioactivity Info	TI LI LO TS
CP0502287 Compound Info	Ac-WVTHRLAGLLS[Cit]SGGVVRKNFVPTDVGPFAF-NH2 Show/Hide	C159H245N45O40	1
1	IC50 = 0.58 nM Bioactivity Info	TI LI LO TS
CP0427227 Compound Info	(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-amino-1-hydroxy-3-(1H-indol-3-yl)propylidene]amino]-1-hydroxy-3-methylbutylidene]amino]-1,3-dihydroxybutylidene]amino]-1-hydroxy-3-(1H-imidazol-5-yl)propylidene]amino]-5-carbamimidamido-1-hydroxypentylidene]amino]-1-hydroxy-4-methylpentylidene]amino]-1-hydroxypropylidene]amino]-1-hydroxyethylidene]amino]-1-hydroxy-4-methylpentylidene]amino]-1-hydroxy-4-methylpentylidene]amino]-1,3-dihydroxypropylidene]amino]-5-carbamimidamido-1-hydroxypentylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxyethylidene]amino]-1-hydroxyethylidene]amino]-1-hydroxy-3-methylbutylidene]amino]-1-hydroxy-3-methylbutylidene]amino]-1-hydroxyhexylidene]amino]-N-[(2S)-1-[(2S)-1-[(2S)-1-[(2S)-2-[N-[(2S,3R)-1-[(2S)-1-[(2S)-1-[2-[(2S)-1-[(2S)-6-amino-1-hydroxy-1-[(2S)-1-hydroxy-1-[(2S)-1-hydroxy-1-imino-3-phenylpropan-2-yl]iminopropan-2-yl]iminohexan-2-yl]imino-1,3-dihydroxypropan-2-yl]imino-2-hydroxyethyl]imino-1-hydroxy-3-methylbutan-2-yl]imino-1,4-dihydroxy-4-iminobutan-2-yl]imino-1,3-dihydroxybutan-2-yl]-C-hydroxycarbonimidoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]imino-1-hydroxy-3-phenylpropan-2-yl]imino-1,4-dihydroxy-4-iminobutan-2-yl]butanediimidic acid Show/Hide	C150H240N46O39	1
1	IC50 = 0.64 nM Bioactivity Info	TI LI LO TS
CP0423722 Compound Info	Ac-VTHRLAGLLSRSGGVVRKNFVPTDVGPFAF-NH2 Show/Hide	C148H236N44O38	1
1	IC50 = 0.71 nM Bioactivity Info	TI LI LO TS
CP0009629 Compound Info	Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVGP[2-Nal]AF-NH2 Show/Hide	C164H248N44O41	2
1	IC50 = 0.79 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.6 nM Bioactivity Info	TI LI LO TS
CP0467357 Compound Info	(3S)-3-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(1H-indol-3-yl)propanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-6-aminohexanoyl]amino]-4-amino-4-oxobutanoyl]amino]-3-phenylpropanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2S)-1-[[2-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid Show/Hide	C163H250N44O41	1
1	IC50 = 0.85 nM Bioactivity Info	TI LI LO TS
CP0423193 Compound Info	Ac-WVEHRLKGELSRKGGVV[hArg]KNFVPTDVGPFAF-NH2 Show/Hide	C166H254N48O39	1
1	IC50 = 1.02 nM Bioactivity Info	TI LI LO TS
CP0296037 Compound Info	4-(2,4-dichlorophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide Show/Hide	C33H42Cl2N6O2	1
1	IC50 = 1.1 nM Bioactivity Info	TI LI LO TS
CP0004918 Compound Info	Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVGPFAF-NH2 Show/Hide	C160H246N44O41	2
1	IC50 = 1.27 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.53 nM Bioactivity Info	TI LI LO TS
CP0467358 Compound Info	(3S)-3-[[(2S,3R)-2-[[1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(1H-indol-3-yl)propanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-6-carbamimidamidohexanoyl]amino]-6-aminohexanoyl]amino]-4-amino-4-oxobutanoyl]amino]-3-phenylpropanoyl]amino]-3-methylbutanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2S)-1-[[2-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid Show/Hide	C168H258N44O41	1
1	IC50 = 1.31 nM Bioactivity Info	TI LI LO TS
CP0423196 Compound Info	Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVGP[Bip]AF-NH2 Show/Hide	C166H250N44O41	1
1	IC50 = 1.56 nM Bioactivity Info	TI LI LO TS
CP0010527 Compound Info	Ac-WVTH[Cit]LAGLLS[Cit]SGGVVRKNFVPTDVGPFAF-NH2 Show/Hide	C159H244N44O41	2
1	IC50 = 1.73 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.46 nM Bioactivity Info	TI LI LO TS
CP0507950 Compound Info	Ac-VTHRLAGLLSRSGGVVKNNFVPTDVGPFAF-NH2 Show/Hide	C146H230N42O39	1
1	IC50 = 1.74 nM Bioactivity Info	TI LI LO TS
CP0468320 Compound Info	Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVGP[1-Nal]AF-NH2 Show/Hide	C163H251N47O39	1
1	IC50 = 1.82 nM Bioactivity Info	TI LI LO TS
CP0468321 Compound Info	Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVG[Thz]FAF-NH2 Show/Hide	C159H244N44O41S	1
1	IC50 = 1.97 nM Bioactivity Info	TI LI LO TS
CP0423192 Compound Info	Ac-WVTH[hArg]LAGLLS[hArg]SGGVVRKNFVPTDVGPFAF-NH2 Show/Hide	C161H250N46O39	1
1	IC50 = 2.1 nM Bioactivity Info	TI LI LO TS
CP0003836 Compound Info	Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVGP[1-Nal]AF-NH Show/Hide	C164H248N44O41	2
1	IC50 = 2.18 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.64 nM Bioactivity Info	TI LI LO TS
CP0011107 Compound Info	(3S)-3-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(1H-indol-3-yl)propanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-6-carbamimidamidohexanoyl]amino]-6-aminohexanoyl]amino]-4-amino-4-oxobutanoyl]amino]-3-phenylpropanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2S)-1-[[2-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid Show/Hide	C164H252N44O41	2
1	IC50 = 2.23 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.73 nM Bioactivity Info	TI LI LO TS
CP0474196 Compound Info	4-(4-fluoro-2-methylsulfonylphenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperazine-1-carboxamide Show/Hide	C33H44FN7O4S	1
1	IC50 = 2.9 nM Bioactivity Info	TI LI LO TS
CP0423725 Compound Info	(3S)-3-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(1H-indol-3-yl)propanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-6-carbamimidamidohexanoyl]amino]-6-aminohexanoyl]amino]-4-amino-4-oxobutanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2S)-1-[[2-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-naphthalen-2-yl-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid Show/Hide	C172H256N44O41	1
1	IC50 = 3.45 nM Bioactivity Info	TI LI LO TS
CP0467356 Compound Info	Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVG[Aib]FAF-NH2 Show/Hide	C159H246N44O41	1
1	IC50 = 3.54 nM Bioactivity Info	TI LI LO TS
CP0003835 Compound Info	(3S)-3-[[(2S,3R)-2-[[1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(1H-indol-3-yl)propanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-6-carbamimidamidohexanoyl]amino]-6-aminohexanoyl]amino]-4-amino-4-oxobutanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-methylbutanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2S)-1-[[2-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-naphthalen-2-yl-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid Show/Hide	C176H262N44O41	2
1	IC50 = 3.57 nM Bioactivity Info	TI LI LO TS
2	Ki = 3.3 nM Bioactivity Info	TI LI LO TS
CP0423194 Compound Info	Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVG[Sar]FAF-NH2 Show/Hide	C158H244N44O41	1
1	IC50 = 3.81 nM Bioactivity Info	TI LI LO TS
CP0423197 Compound Info	(3S)-3-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(1H-indol-3-yl)propanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-6-carbamimidamidohexanoyl]amino]-6-aminohexanoyl]amino]-4-amino-4-oxobutanoyl]amino]-3-phenylpropanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2S)-1-[[2-[(2S)-2-[[(1S)-2-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-(2,3-dihydro-1H-inden-2-yl)-2-oxoethyl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid Show/Hide	C162H248N44O41	1
1	IC50 = 4.15 nM Bioactivity Info	TI LI LO TS
CP0326336 Compound Info	4-(2,4-dichlorophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperazine-1-carboxamide Show/Hide	C32H41Cl2N7O2	1
1	IC50 = 4.3 nM Bioactivity Info	TI LI LO TS
CP0009888 Compound Info	(2S)-N-[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S,3R)-1-[[(2S)-4-amino-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,4-dioxobutan-2-yl]-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]butanediamide Show/Hide	C139H230N44O38	4
1	IC50 = 4.87 nM Bioactivity Info	TI LI LO TS
2	Ki = 3.19 nM Bioactivity Info	TI LI LO TS
3	Ki = 4.5 nM Bioactivity Info	TI LI LO TS
4	Ki = 5.5 nM Bioactivity Info	TI LI LO TS
CP0507948 Compound Info	Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVG[Hyp]FAF-NH2 Show/Hide	C160H246N44O42	1
1	IC50 = 4.98 nM Bioactivity Info	TI LI LO TS
CP0469726 Compound Info	4-(2-chloro-4-methylsulfonylphenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperazine-1-carboxamide Show/Hide	C33H44ClN7O4S	1
1	IC50 = 7 nM Bioactivity Info	TI LI LO TS
CP0512500 Compound Info	4-(2-cyanophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperazine-1-carboxamide Show/Hide	C33H42N8O2	1
1	IC50 = 8.9 nM Bioactivity Info	TI LI LO TS
CP0404535 Compound Info	4-(2-chlorophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide Show/Hide	C33H43ClN6O2	1
1	IC50 = 9.8 nM Bioactivity Info	TI LI LO TS
CP0502288 Compound Info	Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVG[Pip]FAF-NH2 Show/Hide	C161H249N45O41	1
1	IC50 = 11.21 nM Bioactivity Info	TI LI LO TS
CP0226169 Compound Info	4-(2-bromophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperazine-1-carboxamide Show/Hide	C32H42BrN7O2	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0505214 Compound Info	4-(3,4-dichlorophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperazine-1-carboxamide Show/Hide	C32H41Cl2N7O2	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0429248 Compound Info	4-(4-bromophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide Show/Hide	C33H43BrN6O2	1
1	IC50 = 13 nM Bioactivity Info	TI LI LO TS
CP0313182 Compound Info	N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-naphthalen-2-ylpiperidine-1-carboxamide Show/Hide	C37H46N6O2	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0407768 Compound Info	4-(2-chlorophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperazine-1-carboxamide Show/Hide	C32H42ClN7O2	1
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
CP0158318 Compound Info	4-(2-chloro-4-methylphenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide Show/Hide	C34H45ClN6O2	1
1	IC50 = 16 nM Bioactivity Info	TI LI LO TS
CP0100099 Compound Info	4-(3-chlorophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperazine-1-carboxamide Show/Hide	C32H42ClN7O2	1
1	IC50 = 19 nM Bioactivity Info	TI LI LO TS
CP0434878 Compound Info	4-(3,4-dichlorophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide Show/Hide	C33H42Cl2N6O2	1
1	IC50 = 19 nM Bioactivity Info	TI LI LO TS
CP0407767 Compound Info	4-(3-bromophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperazine-1-carboxamide Show/Hide	C32H42BrN7O2	1
1	IC50 = 22 nM Bioactivity Info	TI LI LO TS
CP0296038 Compound Info	4-[2,4-bis(trifluoromethyl)phenyl]-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide Show/Hide	C35H42F6N6O2	1
1	IC50 = 24 nM Bioactivity Info	TI LI LO TS
CP0468322 Compound Info	(3S)-3-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(1H-indol-3-yl)propanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-6-carbamimidamidohexanoyl]amino]-6-aminohexanoyl]amino]-4-amino-4-oxobutanoyl]amino]-3-phenylpropanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2S)-1-[[2-[(3S)-3-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid Show/Hide	C167H249N45O41	1
1	IC50 = 29.73 nM Bioactivity Info	TI LI LO TS
CP0313105 Compound Info	4-(4-bromophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperazine-1-carboxamide Show/Hide	C32H42BrN7O2	1
1	IC50 = 33 nM Bioactivity Info	TI LI LO TS
CP0404536 Compound Info	4-(2-fluoro-4-methylsulfonylphenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperazine-1-carboxamide Show/Hide	C33H44FN7O4S	1
1	IC50 = 34 nM Bioactivity Info	TI LI LO TS
CP0387909 Compound Info	N-[(2R)-3-(3,5-dibromo-4-hydroxyphenyl)-1-(dimethylamino)-1-oxopropan-2-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C25H29Br2N5O4	4
1	IC50 = 41 nM Bioactivity Info	TI LI LO TS
2	Ki = 8 nM Bioactivity Info	TI LI LO TS
3	Ki = 9 nM Bioactivity Info	TI LI LO TS
4	Ki = 9.3 nM Bioactivity Info	TI LI LO TS
CP0519341 Compound Info	4-(4-chlorophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide Show/Hide	C33H43ClN6O2	1
1	IC50 = 41 nM Bioactivity Info	TI LI LO TS
CP0404538 Compound Info	ethyl 4-[4-[[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]carbamoyl]piperazin-1-yl]benzoate Show/Hide	C35H47N7O4	1
1	IC50 = 44 nM Bioactivity Info	TI LI LO TS
CP0573666 Compound Info	N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-phenylpiperazine-1-carboxamide Show/Hide	C32H43N7O2	1
1	IC50 = 44 nM Bioactivity Info	TI LI LO TS
CP0505215 Compound Info	N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(4-phenylphenyl)piperazine-1-carboxamide Show/Hide	C38H47N7O2	1
1	IC50 = 46 nM Bioactivity Info	TI LI LO TS
CP0434879 Compound Info	methyl 2-[1-[[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]carbamoyl]piperidin-4-yl]benzoate Show/Hide	C35H46N6O4	1
1	IC50 = 54 nM Bioactivity Info	TI LI LO TS
CP0505217 Compound Info	4-(4-chlorophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperazine-1-carboxamide Show/Hide	C32H42ClN7O2	1
1	IC50 = 77 nM Bioactivity Info	TI LI LO TS
CP0502289 Compound Info	Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVG[betaPro]FAF-NH2 Show/Hide	C161H248N44O41	1
1	IC50 = 78.9 nM Bioactivity Info	TI LI LO TS
CP0423724 Compound Info	(3S)-3-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(1H-indol-3-yl)propanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]acetyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-6-carbamimidamidohexanoyl]amino]-6-aminohexanoyl]amino]-4-amino-4-oxobutanoyl]amino]-3-phenylpropanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2S)-1-[[2-[(2S)-2-[(3S)-3-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl]-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carbonyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid Show/Hide	C163H247N45O41	1
1	IC50 = 79.34 nM Bioactivity Info	TI LI LO TS
CP0423198 Compound Info	Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVGP[Tic]AF-NH2 Show/Hide	C161H246N44O41	1
1	IC50 = 89.91 nM Bioactivity Info	TI LI LO TS
CP0573665 Compound Info	4-(2,4-difluorophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide Show/Hide	C33H42F2N6O2	1
1	IC50 = 92 nM Bioactivity Info	TI LI LO TS
CP0512499 Compound Info	4-(3,4-difluorophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperazine-1-carboxamide Show/Hide	C32H41F2N7O2	1
1	IC50 = 97 nM Bioactivity Info	TI LI LO TS
CP0565775 Compound Info	4-(4-cyanophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperazine-1-carboxamide Show/Hide	C33H42N8O2	1
1	IC50 = 99 nM Bioactivity Info	TI LI LO TS
CP0505216 Compound Info	methyl 2-[4-[[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]carbamoyl]piperazin-1-yl]benzoate Show/Hide	C34H45N7O4	1
1	IC50 = 110 nM Bioactivity Info	TI LI LO TS
CP0429245 Compound Info	4-(2-fluoro-3-methylphenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide Show/Hide	C34H45FN6O2	1
1	IC50 = 120 nM Bioactivity Info	TI LI LO TS
CP0455576 Compound Info	N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-phenylphenyl)piperazine-1-carboxamide Show/Hide	C38H47N7O2	1
1	IC50 = 120 nM Bioactivity Info	TI LI LO TS
CP0403275 Compound Info	4-(4-fluorophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperazine-1-carboxamide Show/Hide	C32H42FN7O2	1
1	IC50 = 130 nM Bioactivity Info	TI LI LO TS
CP0407764 Compound Info	4-(3-bromophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide Show/Hide	C33H43BrN6O2	1
1	IC50 = 130 nM Bioactivity Info	TI LI LO TS
CP0407766 Compound Info	4-(2-fluorophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperazine-1-carboxamide Show/Hide	C32H42FN7O2	1
1	IC50 = 130 nM Bioactivity Info	TI LI LO TS
CP0455553 Compound Info	4-(2,4-difluorophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperazine-1-carboxamide Show/Hide	C32H41F2N7O2	1
1	IC50 = 140 nM Bioactivity Info	TI LI LO TS
CP0459843 Compound Info	4-(3-chlorophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide Show/Hide	C33H43ClN6O2	1
1	IC50 = 150 nM Bioactivity Info	TI LI LO TS
CP0429246 Compound Info	4-(2-fluorophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperidine-1-carboxamide Show/Hide	C33H43FN6O2	1
1	IC50 = 170 nM Bioactivity Info	TI LI LO TS
CP0469725 Compound Info	N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(2-methylphenyl)piperidine-1-carboxamide Show/Hide	C34H46N6O2	1
1	IC50 = 170 nM Bioactivity Info	TI LI LO TS
CP0512498 Compound Info	4-[3,5-bis(trifluoromethyl)phenyl]-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperazine-1-carboxamide Show/Hide	C34H41F6N7O2	1
1	IC50 = 190 nM Bioactivity Info	TI LI LO TS
CP0404534 Compound Info	N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-(4-methylphenyl)piperidine-1-carboxamide Show/Hide	C34H46N6O2	1
1	IC50 = 240 nM Bioactivity Info	TI LI LO TS
CP0459844 Compound Info	4-(2,3-dichlorophenyl)-N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]piperazine-1-carboxamide Show/Hide	C32H41Cl2N7O2	1
1	IC50 = 350 nM Bioactivity Info	TI LI LO TS
CP0573664 Compound Info	N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-naphthalen-1-ylpiperidine-1-carboxamide Show/Hide	C37H46N6O2	1
1	IC50 = 430 nM Bioactivity Info	TI LI LO TS
CP0434881 Compound Info	N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-piperidin-1-ylpiperidin-1-yl)propan-2-yl]-4-phenylpiperidine-1-carboxamide Show/Hide	C33H44N6O2	1
1	IC50 = 460 nM Bioactivity Info	TI LI LO TS
CP0009514 Compound Info	(3S)-3-[[(2S,3R)-2-[[2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]-2-methylpropanoyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2S)-1-[[2-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid Show/Hide	C59H81N11O15	1
1	IC50 = 740 nM Bioactivity Info	TI LI LO TS
CP0391056 Compound Info	N-[2-(1-adamantylamino)-2-oxoethyl]-4-bromo-6-(1,1-dioxothiazinan-2-yl)-3-hydroxypyridine-2-carboxamide Show/Hide	C22H29BrN4O5S	4
1	IC50 = 2100 nM Bioactivity Info	TI LI LO TS
2	Ki = 710 nM Bioactivity Info	TI LI LO TS
3	Ki = 840 nM Bioactivity Info	TI LI LO TS
4	Ki = 5600 nM Bioactivity Info	TI LI LO TS
CP0393463 Compound Info	4-bromo-N-[2-(cyclobutylamino)-2-oxoethyl]-6-(1,1-dioxothiazinan-2-yl)-3-hydroxypyridine-2-carboxamide Show/Hide	C16H21BrN4O5S	2
1	IC50 = 2400 nM Bioactivity Info	TI LI LO TS
2	Ki = 1800 nM Bioactivity Info	TI LI LO TS
CP0401340 Compound Info	N-[(3,5-difluorophenyl)methyl]-5-(1,1-dioxothiazinan-2-yl)-8-hydroxy-1,6-naphthyridine-7-carboxamide Show/Hide	C20H18F2N4O4S	2
1	IC50 = 2600 nM Bioactivity Info	TI LI LO TS
2	Ki = 1900 nM Bioactivity Info	TI LI LO TS
CP0298816 Compound Info	4-bromo-N-[(3,5-difluorophenyl)methyl]-6-(1,1-dioxothiazinan-2-yl)-3-hydroxypyridine-2-carboxamide Show/Hide	C17H16BrF2N3O4S	4
1	IC50 = 2700 nM Bioactivity Info	TI LI LO TS
2	Ki = 2700 nM Bioactivity Info	TI LI LO TS
3	Ki = 3300 nM Bioactivity Info	TI LI LO TS
4	Ki > 100000 nM Bioactivity Info	TI LI LO TS
CP0387908 Compound Info	tert-butyl 2-[[4-bromo-6-(1,1-dioxothiazinan-2-yl)-3-hydroxypyridine-2-carbonyl]amino]acetate Show/Hide	C16H22BrN3O6S	2
1	IC50 = 9800 nM Bioactivity Info	TI LI LO TS
2	Ki = 1700 nM Bioactivity Info	TI LI LO TS
CP0401345 Compound Info	5-(1,1-dioxothiazinan-2-yl)-N-[(3-fluorophenyl)methyl]-8-hydroxy-1,6-naphthyridine-7-carboxamide Show/Hide	C20H19FN4O4S	2
1	IC50 > 10000 nM Bioactivity Info	TI LI LO TS
2	Ki = 5200 nM Bioactivity Info	TI LI LO TS
CP0463145 Compound Info	tert-butyl 2-[[5-(1,1-dioxothiazinan-2-yl)-8-hydroxy-1,6-naphthyridine-7-carbonyl]amino]acetate Show/Hide	C19H24N4O6S	2
1	IC50 > 10000 nM Bioactivity Info	TI LI LO TS
2	Ki = 8000 nM Bioactivity Info	TI LI LO TS
CP0523753 Compound Info	4-bromo-N-[2-(tert-butylamino)-2-oxoethyl]-6-(1,1-dioxothiazinan-2-yl)-3-hydroxypyridine-2-carboxamide Show/Hide	C16H23BrN4O5S	2
1	IC50 > 10000 nM Bioactivity Info	TI LI LO TS
2	Ki = 11000 nM Bioactivity Info	TI LI LO TS
CP0055455 Compound Info	5-(1,1-dioxo-1,2-thiazinan-2-yl)-N-[(4-fluorophenyl)methyl]-8-hydroxy-1,6-naphthyridine-7-carboxamide Show/Hide	C20H19FN4O4S	2
1	IC50 = 28000 nM Bioactivity Info	TI LI LO TS
2	Ki = 7300 nM Bioactivity Info	TI LI LO TS
CP0927092 Compound Info	Ac-WVTH[Cit]LAGLLS[Cit]SGGVV[hArg]KNFVPTDVGpFAF-NH2 Show/Hide	C160H246N44O41	1
1	IC50 >= 1000 nM Bioactivity Info	TI LI LO TS
CP0391033 Compound Info	(3S)-4-[[(2S,3R)-1-[[(2S)-1-[[(2S,3R)-1-[[(2R)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-4-amino-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S,3R)-1-[[(2S)-4-amino-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-[[(2R)-2-[[(2S)-2-aminopropanoyl]amino]-3-sulfanylpropanoyl]amino]-4-oxobutanoic acid Show/Hide	C163H269N51O49S2	1
1	Ki = 0.01 nM Bioactivity Info	TI LI LO TS
CP0000982 Compound Info	N-[(2R)-1-[[(2S)-6-amino-1-oxo-1-(4-pyridin-4-ylpiperazin-1-yl)hexan-2-yl]amino]-3-(3,5-dibromo-4-hydroxyphenyl)-1-oxopropan-2-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide Show/Hide	C38H47Br2N9O5	1
1	Ki = 0.014 nM Bioactivity Info	TI LI LO TS
CP0003456 Compound Info	2-[(8R)-8-(3,5-difluorophenyl)-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-N-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide Show/Hide	C31H29F2N5O3	1
1	Ki = 0.024 nM Bioactivity Info	TI LI LO TS
CP0024947 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C26H27F5N6O3	1
1	Ki = 0.78 nM Bioactivity Info	TI LI LO TS
CP0463144 Compound Info	5-(1,1-dioxothiazinan-2-yl)-8-hydroxy-N-(pyridin-3-ylmethyl)-1,6-naphthyridine-7-carboxamide Show/Hide	C19H19N5O4S	1
1	Ki = 14000 nM Bioactivity Info	TI LI LO TS
CP0332853 Compound Info	N-benzyl-5-(1,1-dioxothiazinan-2-yl)-8-hydroxy-1,6-naphthyridine-7-carboxamide Show/Hide	C20H20N4O4S	1
1	Ki = 16000 nM Bioactivity Info	TI LI LO TS
CP0391055 Compound Info	1-(1,1-dioxothiazinan-2-yl)-N-[(3-fluorophenyl)methyl]-4-hydroxyisoquinoline-3-carboxamide Show/Hide	C21H20FN3O4S	1
1	Ki = 26000 nM Bioactivity Info	TI LI LO TS
CP0432816 Compound Info	N-[(3,5-difluorophenyl)methyl]-6-(1,1-dioxothiazinan-2-yl)-3-hydroxypyridine-2-carboxamide Show/Hide	C17H17F2N3O4S	1
1	Ki = 45000 nM Bioactivity Info	TI LI LO TS
CP0387910 Compound Info	N-[(3,5-difluorophenyl)methyl]-5-(1,1-dioxothiazinan-2-yl)-8-hydroxyquinoline-7-carboxamide Show/Hide	C21H19F2N3O4S	1
1	Ki > 100000 nM Bioactivity Info	TI LI LO TS
CP0387912 Compound Info	4-bromo-N-[(3,5-difluorophenyl)methyl]-6-(1,1-dioxothiazinan-2-yl)-3-methoxypyridine-2-carboxamide Show/Hide	C18H18BrF2N3O4S	1
1	Ki > 100000 nM Bioactivity Info	TI LI LO TS
CP0440299 Compound Info	(3,5-difluorophenyl)methyl 5-(1,1-dioxothiazinan-2-yl)-8-hydroxy-1,6-naphthyridine-7-carboxylate Show/Hide	C20H17F2N3O5S	1
1	Ki > 100000 nM Bioactivity Info	TI LI LO TS
CP0456637 Compound Info	5-(1,1-dioxothiazinan-2-yl)-N-[(4-fluorophenyl)methyl]-1,6-naphthyridine-7-carboxamide Show/Hide	C20H19FN4O3S	1
1	Ki > 100000 nM Bioactivity Info	TI LI LO TS

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han