Brief Information of the Compound and Protein
Compound Name
N-[(2R)-3-(3,5-dibromo-4-hydroxyphenyl)-1-(dimethylamino)-1-oxopropan-2-yl]-4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxamide
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PubChem ID
CID: 57400721
Canonical SMILES
CN(C)C(=O)[C@@H](Cc1cc(Br)c(O)c(Br)c1)NC(=O)N1CCC(CC1)N1Cc2ccccc2NC1=O
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Compound Formula C25H29Br2N5O4
Compound Structure
Protein Name
Calcitonin gene-related peptide 1
Protein Classification
Secreted protein
Uniprot ID
P06881
Gene Name
CALCA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  4
1
IC50 = 41 nM
   TI
   LI
   LO
   TS
2
Ki = 8 nM
   TI
   LI
   LO
   TS
3
Ki = 9 nM
   TI
   LI
   LO
   TS
4
Ki = 9.3 nM
   TI
   LI
   LO
   TS