Brief Information of the Compound and Protein
Compound Name
N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
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PubChem ID
CID: 11319053
SID: 50086919
Canonical SMILES
Fc1cccc([C@@H]2CC[C@@H](NC(=O)N3CCC(CC3)n3c4cccnc4[nH]c3=O)C(=O)N(CC(F)(F)F)C2)c1F
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Compound Formula C26H27F5N6O3
Compound Structure
Protein Name
Calcitonin gene-related peptide 1
Protein Classification
Secreted protein
Uniprot ID
P06881
Gene Name
CALCA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 2.2 nM
   TI
   LI
   LO
   TS
2
Ki > 100000 nM
   TI
   LI
   LO
   TS
CL000074 SK-N-MC Homo sapiens (Human)  1
1
Ki = 0.78 nM
   TI
   LI
   LO
   TS