Brief Information of the Compound and Protein
Compound Name
2-[(7-methyl-1H-indazol-5-yl)methyl]-4-(2-oxospiro[1,3-dihydroquinazoline-4,4'-piperidine]-1'-yl)-1-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione
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PubChem ID
CID: 11169454
SID: 16248949
Canonical SMILES
Cc1cc(CC(CC(=O)N2CCC3(CC2)NC(=O)Nc2ccccc32)C(=O)N2CCC(CC2)N2CCCCC2)cc2cn[nH]c12
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Compound Formula C35H45N7O3
Compound Structure
Protein Name
Calcitonin gene-related peptide type 1 receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Calcitonin-like receptor
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Calcitonin gene-related peptide receptor
Uniprot ID
Q16602
Gene Name
CALCRL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  2
1
IC50 = 0.34 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.35 nM
   TI
   LI
   LO
   TS