Brief Information of the Compound and Protein
Compound Name
2-[(7-methyl-1H-indazol-5-yl)methyl]-4-(2-oxospiro[1H-3,1-benzoxazine-4,4'-piperidine]-1'-yl)-1-piperidin-1-ylbutane-1,4-dione
    Show/Hide
PubChem ID
CID: 24756768
SID: 49660206
Canonical SMILES
Cc1cc(CC(CC(=O)N2CCC3(CC2)OC(=O)Nc2ccccc32)C(=O)N2CCCCC2)cc2cn[nH]c12
    Show/Hide
Compound Formula C30H35N5O4
Compound Structure
Protein Name
Calcitonin gene-related peptide type 1 receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Calcitonin-like receptor
>
Calcitonin gene-related peptide receptor
Uniprot ID
Q16602
Gene Name
CALCRL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  2
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
2
IC50 = 34 nM
   TI
   LI
   LO
   TS