Brief Information of the Compound and Protein
Compound Name
[2-(7-methyl-1H-indazol-5-yl)-1-[4-(piperidine-1-carbonyl)pyridin-2-yl]ethyl] 4-(2-oxo-1,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate
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PubChem ID
CID: 11308069
SID: 16396572
Canonical SMILES
Cc1cc(CC(OC(=O)N2CCC(CC2)N2Cc3ccccc3NC2=O)c2cc(ccn2)C(=O)N2CCCCC2)cc2cn[nH]c12
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Compound Formula C35H39N7O4
Compound Structure
Protein Name
Calcitonin gene-related peptide type 1 receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Calcitonin-like receptor
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Calcitonin gene-related peptide receptor
Uniprot ID
Q16602
Gene Name
CALCRL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  2
1
IC50 = 0.099 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.28 nM
   TI
   LI
   LO
   TS