Brief Information of the Compound and Protein
Compound Name
[1-[6-chloro-4-(dimethylcarbamoyl)pyridin-2-yl]-2-(7-methyl-1H-indazol-5-yl)ethyl] 4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxylate
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PubChem ID
CID: 70685595
Canonical SMILES
CN(C)C(=O)c1cc(Cl)nc(c1)C(Cc1cc(C)c2[nH]ncc2c1)OC(=O)N1CCC(CC1)c1cc2ccccc2[nH]c1=O
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Compound Formula C33H33ClN6O4
Compound Structure
Protein Name
Calcitonin gene-related peptide type 1 receptor
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Calcitonin-like receptor
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Calcitonin gene-related peptide receptor
Uniprot ID
Q16602
Gene Name
CALCRL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  3
1
IC50 = 0.28 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.34 nM
   TI
   LI
   LO
   TS
3
Ki = 3.3 nM
   TI
   LI
   LO
   TS