Brief Information of the Compound and Protein
Compound Name
(5-Iodo-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
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PubChem ID
CID: 44395308
Canonical SMILES
CN1CCN(C(=O)c2cc3cc(I)ccc3[nH]2)CC1
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Compound Formula C14H16IN3O
Compound Structure
Protein Name
Histamine H3 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  2
1
EC50 = 3162.28 nM
   TI
   LI
   LO
   TS
2
Ki = 2511.89 nM
   TI
   LI
   LO
   TS