Brief Information of the Compound and Protein
Compound Name
3-(5-(4-cyclopropyl-1,4-diazepane-1-carbonyl)pyridin-2-yloxy)benzonitrile
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PubChem ID
CID: 24771308
SID: 49692740
Canonical SMILES
O=C(N1CCCN(CC1)C1CC1)c1ccc(Oc2cccc(c2)C#N)nc1
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Compound Formula C21H22N4O2
Compound Structure
Protein Name
Histamine H3 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  2
1
Kd = 2.951 nM
   TI
   LI
   LO
   TS
2
Ki = 12 nM
   TI
   LI
   LO
   TS