Brief Information of the Compound and Protein
Compound Name
(4-cyclobutyl-1,4-diazepan-1-yl)(5-(2-fluorophenoxy)pyridin-2-yl)methanone
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PubChem ID
CID: 24770908
SID: 49692315
Canonical SMILES
Fc1ccccc1Oc1ccc(nc1)C(=O)N1CCCN(CC1)C1CCC1
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Compound Formula C21H24FN3O2
Compound Structure
Protein Name
Histamine H3 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  2
1
Kd = 0.537 nM
   TI
   LI
   LO
   TS
2
Ki = 4.3 nM
   TI
   LI
   LO
   TS