Brief Information of the Compound and Protein
Compound Name
Imifuramine
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PubChem ID
CID: 10197870
SID: 15194977
Canonical SMILES
NC[C@H]1CC[C@@H](O1)c1c[nH]cn1
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Compound Formula C8H13N3O
Compound Structure
Protein Name
Histamine H3 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  3
1
EC50 = 39.81 nM
   TI
   LI
   LO
   TS
2
EC50 = 44.67 nM
   TI
   LI
   LO
   TS
3
Ki = 251.19 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 229.09 nM