Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-cyano-3-[[(2R,5R)-5-(1H-imidazol-5-yl)oxolan-2-yl]methyl]-2-methylguanidine
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 PubChem ID
CID: 10106063
SID: 15094307
Canonical SMILES
C\N=C(\NC[C@H]1CC[C@@H](O1)c1c[nH]cn1)NC#N
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Compound Formula C11H16N6O
Compound Structure
Protein Name
 Protein Info 
Histamine H3 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 3162.28 nM
   TI
   LI
   LO
   TS
2
Ki = 1995.26 nM
   TI
   LI
   LO
   TS
3
Ki = 2200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 2187.76 nM