Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-cyano-3-[[(2S,5S)-5-(1H-imidazol-5-yl)oxolan-2-yl]methyl]-2-methylguanidine
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 PubChem ID
CID: 10879463
SID: 15925329
Canonical SMILES
C\N=C(\NC[C@@H]1CC[C@H](O1)c1c[nH]cn1)NC#N
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Compound Formula C11H16N6O
Compound Structure
Protein Name
 Protein Info 
Histamine H3 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
2
EC50 < 100000 nM
   TI
   LI
   LO
   TS
3
Ki = 19952.62 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 18620.87 nM