Brief Information of the Compound and Protein
Compound Name
N,N-diethyl-3-[(6-methyl-8-phenyl-7,8-dihydro-5H-2,6-naphthyridin-3-yl)oxy]propan-1-amine
    Show/Hide
PubChem ID
CID: 15983457
SID: 24262475
Canonical SMILES
CCN(CC)CCCOc1cc2CN(C)CC(c3ccccc3)c2cn1
    Show/Hide
Compound Formula C22H31N3O
Compound Structure
Protein Name
Histamine H3 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  2
1
Kd = 0.6607 nM
   TI
   LI
   LO
   TS
2
Ki = 4 nM
   TI
   LI
   LO
   TS