General Information of the Compound
| Compound ID |
CP0058845
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| Compound Name |
4-[(3R)-3-aminopyrrolidin-1-yl]-6-propan-2-ylpyrimidin-2-amine
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| Synonyms |
JNJ-39758979
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| Structure |
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| Formula |
C11H19N5
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| Molecular Weight |
221.308
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| Canonical SMILES |
CC(C)c1cc(nc(N)n1)N1CC[C@@H](N)C1
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| InChI |
InChI=1S/C11H19N5/c1-7(2)9-5-10(15-11(13)14-9)16-4-3-8(12)6-16/h5,7-8H,3-4,6,12H2,1-2H3,(H2,13,14,15)/t8-/m1/s1
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| InChIKey |
COOGVHJHSCBOQT-MRVPVSSYSA-N
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| CAS |
1046447-90-8
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01194, Histamine H3 receptor
Protein ID: PT04730, Histamine H4 receptor
Protein ID: PT01711, Histamine H4 receptor
Protein ID: PT02519, Histamine H4 receptor
Clinical Information about the Compound