Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[(3R)-3-aminopyrrolidin-1-yl]-6-propan-2-ylpyrimidin-2-amine
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 PubChem ID
CID: 24994634
SID: 56336654
Canonical SMILES
CC(C)c1cc(nc(N)n1)N1CC[C@@H](N)C1
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Compound Formula C11H19N5
Compound Structure
Protein Name
 Protein Info 
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
>
Histamine receptor
Uniprot ID
Q91ZY2
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC
 Cell Line Info 
Homo sapiens (Human)  2
1
Kd = 5.012 nM
   TI
   LI
   LO
   TS
2
Ki = 5.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8 nM
2 Ki = 5.3 nM