General Information of the Compound
Compound ID
CP0441099
Compound Name
2-((1H-imidazol-4-yl)methyl)pyridine
    Show/Hide
Synonyms
2-((1H-imidazol-4-yl)methyl)pyridine
BDBM50326296
CHEMBL81644
    Show/Hide
Structure
Formula
C9H9N3
Molecular Weight
159.192
Canonical SMILES
C(c1cnc[nH]1)c1ccccn1
    Show/Hide
InChI
InChI=1S/C9H9N3/c1-2-4-11-8(3-1)5-9-6-10-7-12-9/h1-4,6-7H,5H2,(H,10,12)
    Show/Hide
InChIKey
YSOIYRCVNZBHGT-UHFFFAOYSA-N
Physicochemical Property
logP
1.3955
Rotatable Bonds
2
Heavy Atom Count
12
Polar Areas
41.57
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
12

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 9877454
SID: 16349292
ChEMBL ID
CHEMBL81644
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01194, Histamine H3 receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  2
1
EC50 = 602.56 nM
   TI
   LI
   LO
   TS
2
Ki = 588.84 nM
   TI
   LI
   LO
   TS
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 1300 nM
   TI
   LI
   LO
   TS
2
Ki = 1800 nM
   TI
   LI
   LO
   TS
Protein ID: PT01711, Histamine H4 receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  2
1
EC50 = 10471.29 nM
   TI
   LI
   LO
   TS
2
Ki = 4570.88 nM
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( 2-((1H-imidazol-4-yl)methyl)pyridine )
Drug Name 2-((1H-imidazol-4-yl)methyl)pyridine
Target(s)
Histamine H3 receptor (H3R)
Inhibitor