Brief Information of the Compound and Protein
Compound Name
 Compound Info 
((2R,4S)-4-(4-chlorophenoxy)pyrrolidin-2-yl)(4-cyclobutyl-1,4-diazepan-1-yl)methanone
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 PubChem ID
CID: 46887963
Canonical SMILES
Clc1ccc(O[C@@H]2CN[C@H](C2)C(=O)N2CCCN(CC2)C2CCC2)cc1
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Compound Formula C20H28ClN3O2
Compound Structure
Protein Name
 Protein Info 
Histamine H3 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC
 Cell Line Info 
Homo sapiens (Human)  1
1
Kd = 0.955 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 2 nM