General Information of the Compound
| Compound ID |
CP0044460
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| Compound Name |
N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide
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| Synonyms |
1-Piperidinecarbothioamide, N-cyclohexyl-4-(1H-imidazol-4-yl)-
106243-16-7
AC1MI071
BDBM22914
CHEBI:81391
CHEMBL260374
DTXSID50147555
GTPL1267
II4319BWUI
Lopac-T-123
Lopac0_001214
MR 12842
MolPort-015-163-994
MolPort-023-275-907
N-Cyclohexy-4-(imidazol-4-yl)-1-piperidinecarbothioamide
N-Cyclohexyl-4-(1H-imidazol-5-yl)-1-piperidinecarbothioamide
N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide
SCHEMBL2235762
Thioperamide
Thioperamide maleate
Tocris-0644
UNII-II4319BWUI
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| Structure |
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| Formula |
C15H24N4S
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| Molecular Weight |
292.452
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| Canonical SMILES |
S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1
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| InChI |
InChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20)
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| InChIKey |
QKDDJDBFONZGBW-UHFFFAOYSA-N
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| CAS |
106243-16-7
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01650, Alpha-2A adrenergic receptor
Protein ID: PT01598, Alpha-2C adrenergic receptor
Protein ID: PT04604, Cholesterol 24-hydroxylase
Protein ID: PT01206, Histamine H1 receptor
Protein ID: PT03665, Histamine H3 receptor
Protein ID: PT01194, Histamine H3 receptor
Cell-based Assay
Protein ID: PT01173, Histamine H3 receptor
Protein ID: PT04730, Histamine H4 receptor
Cell-based Assay
Protein ID: PT01711, Histamine H4 receptor
Cell-based Assay
Clinical Information about the Compound