Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide
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 PubChem ID
CID: 3035905
SID: 14922586
Canonical SMILES
S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1
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Compound Formula C15H24N4S
Compound Structure
Protein Name
 Protein Info 
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q91ZY2
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 66.07 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 28.18 nM
   TI
   LI
   LO
   TS
CL000904 HEK293-SF-mH4R-His6-CRE-Luc
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 302 nM
   TI
   LI
   LO
   TS
CL000909 HEK293T-SF-His6-CRE-Luc
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 79.43 nM
   TI
   LI
   LO
   TS