General Information of the Compound
Compound ID
CP0386069
Compound Name
N-ethyl-N-[[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]methyl]ethanamine
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Structure
Formula
C23H32N2
Molecular Weight
336.523
Canonical SMILES
CCN(CC)Cc1ccc(cc1)-c1ccc(CN2CCCCC2)cc1
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InChI
InChI=1S/C23H32N2/c1-3-24(4-2)18-20-8-12-22(13-9-20)23-14-10-21(11-15-23)19-25-16-6-5-7-17-25/h8-15H,3-7,16-19H2,1-2H3
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InChIKey
JNCUXGASTFMNNI-UHFFFAOYSA-N
Physicochemical Property
logP
5.1813
Rotatable Bonds
7
Heavy Atom Count
25
Polar Areas
6.48
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44588217
ChEMBL ID
CHEMBL457007
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01194, Histamine H3 receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  1
1
Ki = 1.95 nM
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