General Information of the Compound
Compound ID
CP0386084
Compound Name
N-[[4-[4-[(cyclohexylamino)methyl]phenyl]phenyl]methyl]cyclohexanamine
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Structure
Formula
C26H36N2
Molecular Weight
376.588
Canonical SMILES
C(NC1CCCCC1)c1ccc(cc1)-c1ccc(CNC2CCCCC2)cc1
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InChI
InChI=1S/C26H36N2/c1-3-7-25(8-4-1)27-19-21-11-15-23(16-12-21)24-17-13-22(14-18-24)20-28-26-9-5-2-6-10-26/h11-18,25-28H,1-10,19-20H2
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InChIKey
DEHUWVFAQOAJBV-UHFFFAOYSA-N
Physicochemical Property
logP
6.1982
Rotatable Bonds
7
Heavy Atom Count
28
Polar Areas
24.06
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44414417
ChEMBL ID
CHEMBL447846
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01194, Histamine H3 receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  1
1
Ki = 562.34 nM
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