Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-indole
    Show/Hide
 PubChem ID
CID: 4908365
SID: 125299313
Canonical SMILES
CN1CCN(CC1)C(=O)c1cc2cc(Cl)ccc2[nH]1
    Show/Hide
Compound Formula C14H16ClN3O
Compound Structure
Protein Name
 Protein Info 
Histamine H3 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 5011.87 nM
   TI
   LI
   LO
   TS
CL000074 SK-N-MC
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 1000 nM
   TI
   LI
   LO
   TS
2
Ki = 1995.26 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 2238.72 nM
2 Ki = 5125 nM