| Compound ID |
Compound Name |
Compound Formula |
|
CP0270460
|
3-[4-(5-fluoro-4-methyl-1H-benzimidazol-2-yl)-3-methylphenoxy]-N-[2-(1H-imidazol-5-yl)ethyl]propan-1-amine
Show/Hide
|
C23H26FN5O
|
1
|
| 1 |
EC50 = 0.56 nM
|
|
|
|
CP0213380
|
5-(3-(4-(5-fluoro-4-methyl-1H-benzo[d]imidazol-2-yl)-3-methylphenoxy)propyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine
Show/Hide
|
C24H26FN5O
|
1
|
| 1 |
EC50 = 3.3 nM
|
|
|
|
CP0288245
|
3-(4-(5-fluoro-4-methyl-1H-benzo[d]imidazol-2-yl)-3-methylphenoxy)-N-(pyridin-3-ylmethyl)propan-1-amine
Show/Hide
|
C24H25FN4O
|
1
|
| 1 |
EC50 = 3.3 nM
|
|
|
|
CP0089117
|
N-butyl-4-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine
Show/Hide
|
C13H23N5
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0415218
|
(+/-)-3-(4-(5-fluoro-4-methyl-1H-benzo[d]imidazol-2-yl)-3-methylphenoxy)-N-(piperidin-3-ylmethyl)propan-1-amine
Show/Hide
|
C24H31FN4O
|
1
|
| 1 |
EC50 = 6.9 nM
|
|
|
|
CP0242757
|
6-N-cyclopentyl-4-(4-methylpiperazin-1-yl)pyridine-2,6-diamine
Show/Hide
|
C15H25N5
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0346009
|
6-(4-methylpiperazin-1-yl)-4-N-propan-2-ylpyrimidine-2,4-diamine
Show/Hide
|
C12H22N6
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0098027
|
2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide
Show/Hide
|
C6H10N4S
|
3
|
| 1 |
EC50 = 12.59 nM
|
|
|
| 2 |
Ki = 3.6 nM
|
|
|
| 3 |
Ki = 6.31 nM
|
|
|
|
CP0214392
|
5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole
Show/Hide
|
C13H15IN2O
|
1
|
| 1 |
EC50 = 12.59 nM
|
|
|
|
CP0437514
|
VUF 8328
Show/Hide
|
C7H12N4S
|
2
|
| 1 |
EC50 = 12.59 nM
|
|
|
| 2 |
Ki = 12.59 nM
|
|
|
|
CP0853195
|
4,7-dichloro-11-(4-methylpiperazin-1-yl)-dibenzo[b,f][1,4]oxazepine
Show/Hide
|
C18H17Cl2N3O
|
2
|
| 1 |
EC50 = 14.79 nM
|
|
|
| 2 |
Ki = 45.71 nM
|
|
|
|
CP0897701
|
8-chloro-4-Fluoro-11-(4-methylpiperazin-1-yl)-dibenzo[b,f][1,4]oxazepine
Show/Hide
|
C18H17ClFN3O
|
2
|
| 1 |
EC50 = 14.79 nM
|
|
|
| 2 |
Ki = 27.54 nM
|
|
|
|
CP0116622
|
4-[(3R)-3-(methylamino)pyrrolidin-1-yl]-N-(2-methylpropyl)pyrimidin-2-amine
Show/Hide
|
C13H23N5
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0110239
|
4-(1H-imidazol-4-ylmethyl)piperidine
Show/Hide
|
C9H15N3
|
4
|
| 1 |
EC50 = 15.85 nM
|
|
|
| 2 |
EC50 = 56.23 nM
|
|
|
| 3 |
Ki = 19.95 nM
|
|
|
| 4 |
Ki = 21.88 nM
|
|
|
|
CP0303224
|
2-N-cyclopentyl-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C14H24N6
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0180153
|
7-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepine
Show/Hide
|
C18H18ClN3O
|
6
|
| 1 |
EC50 = 19.95 nM
|
|
|
| 2 |
Kd = 10.7 nM
|
|
|
| 3 |
Kd = 13 nM
|
|
|
| 4 |
Kd = 22.2 nM
|
|
|
| 5 |
Kd = 72 nM
|
|
|
| 6 |
Ki = 28.18 nM
|
|
|
|
CP0036920
|
2-(1H-imidazol-4-yl)ethan-1-amine
Show/Hide
|
C5H9N3
|
9
|
| 1 |
EC50 = 19.95 nM
|
|
|
| 2 |
EC50 = 20.89 nM
|
|
|
| 3 |
EC50 = 54.95 nM
|
|
|
| 4 |
EC50 = 79.43 nM
|
|
|
| 5 |
Ki = 7.943 nM
|
|
|
| 6 |
Ki = 12.59 nM
|
|
|
| 7 |
Ki = 13.4 nM
|
|
|
| 8 |
Ki = 14.45 nM
|
|
|
| 9 |
Ki = 15.85 nM
|
|
|
|
CP0057002
|
1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea
Show/Hide
|
C9H16N4S
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
|
CP0412799
|
1-[4-(1H-imidazol-4-yl)butyl]-3-propan-2-ylthiourea
Show/Hide
|
C11H20N4S
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
|
CP0437516
|
Clobenprobit
Show/Hide
|
C15H19ClN4S
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
|
CP0398278
|
N-(2-bicyclo[2.2.1]heptanyl)-4-(4-methylpiperazin-1-yl)pyrimidin-2-amine
Show/Hide
|
C16H25N5
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0930756
|
7-chloro-4-fluoro-11-(4-methylpiperazin-1-yl)-dibenzo[b,f][1,4]oxazepine
Show/Hide
|
C18H17ClFN3O
|
2
|
| 1 |
EC50 = 20.42 nM
|
|
|
| 2 |
Ki = 30.9 nM
|
|
|
|
CP0247767
|
4-[(3R)-3-(methylamino)pyrrolidin-1-yl]-N-propan-2-ylpyrimidin-2-amine
Show/Hide
|
C12H21N5
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0186261
|
2-[3-(1H-imidazol-5-yl)propyl]-1-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine
Show/Hide
|
C14H23N7S
|
1
|
| 1 |
EC50 = 25.12 nM
|
|
|
|
CP0005613
|
8-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepine
Show/Hide
|
C18H18ClN3O
|
2
|
| 1 |
EC50 = 28.18 nM
|
|
|
| 2 |
Ki = 42.66 nM
|
|
|
|
CP0185384
|
4-(1H-imidazol-5-yl)butan-1-amine
Show/Hide
|
C7H13N3
|
5
|
| 1 |
EC50 = 31.62 nM
|
|
|
| 2 |
EC50 = 89.13 nM
|
|
|
| 3 |
Ki = 10 nM
|
|
|
| 4 |
Ki = 12.7 nM
|
|
|
| 5 |
Ki = 14.45 nM
|
|
|
|
CP0883850
|
7-chloro-3-fluoro-11-(4-methylpiperazin-1-yl)-dibenzo[b,f][1,4]oxazepine
Show/Hide
|
C18H17ClFN3O
|
2
|
| 1 |
EC50 = 38.9 nM
|
|
|
| 2 |
Ki = 38.9 nM
|
|
|
|
CP0439321
|
(NZ)-N-[(5-chloro-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methylidene]hydroxylamine
Show/Hide
|
C14H17ClN4O
|
2
|
| 1 |
EC50 = 39.81 nM
|
|
|
| 2 |
Ki = 31.62 nM
|
|
|
|
CP0398855
|
2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine
Show/Hide
|
C6H11N3
|
1
|
| 1 |
EC50 = 39.81 nM
|
|
|
|
CP0089184
|
N-butyl-4-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyridin-2-amine
Show/Hide
|
C14H24N4
|
1
|
| 1 |
EC50 = 48 nM
|
|
|
|
CP0288241
|
5-fluoro-4-methyl-2-(2-methyl-4-(3-(4-methylpiperazin-1-yl)propoxy)phenyl)-1H-benzo[d]imidazole
Show/Hide
|
C23H29FN4O
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0242755
|
4-(4-methylpiperazin-1-yl)-6-N-(2-methylpropyl)pyridine-2,6-diamine
Show/Hide
|
C14H25N5
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0202795
|
2-(diaminomethylideneamino)ethyl carbamimidothioate
Show/Hide
|
C4H11N5S
|
1
|
| 1 |
EC50 = 50.12 nM
|
|
|
|
CP0221940
|
1-(3-(4-(5-fluoro-4-methyl-1H-benzo[d]imidazol-2-yl)-3-methylphenoxy)propyl)-N-methylpyrrolidin-3-amine
Show/Hide
|
C23H29FN4O
|
1
|
| 1 |
EC50 = 62 nM
|
|
|
|
CP0213459
|
3-(1H-imidazol-4-yl)propylphenylmethyl ether
Show/Hide
|
C13H16N2O
|
1
|
| 1 |
EC50 = 63.1 nM
|
|
|
|
CP0377744
|
1-[(4-chlorophenyl)methyl]-3-[5-(1H-imidazol-4-yl)pentyl]thiourea
Show/Hide
|
C16H21ClN4S
|
1
|
| 1 |
EC50 = 63.1 nM
|
|
|
|
CP0437519
|
1-[4-(1H-imidazol-4-yl)butyl]-3-propylthiourea
Show/Hide
|
C11H20N4S
|
1
|
| 1 |
EC50 = 63.1 nM
|
|
|
|
CP0115852
|
N-cyclopentyl-4-(4-methylpiperazin-1-yl)pyrimidin-2-amine
Show/Hide
|
C14H23N5
|
1
|
| 1 |
EC50 = 75 nM
|
|
|
|
CP0100890
|
1-cyano-3-[[(2R,5R)-5-(1H-imidazol-5-yl)oxolan-2-yl]methyl]-2-methylguanidine
Show/Hide
|
C11H16N6O
|
4
|
| 1 |
EC50 = 77.62 nM
|
|
|
| 2 |
EC50 = 78 nM
|
|
|
| 3 |
EC50 = 79.43 nM
|
|
|
| 4 |
Ki = 125 nM
|
|
|
|
CP0412802
|
(NZ)-N-[(6-chloro-1H-benzimidazol-2-yl)-(1-methylpiperidin-4-yl)methylidene]hydroxylamine
Show/Hide
|
C14H17ClN4O
|
2
|
| 1 |
EC50 = 79.43 nM
|
|
|
| 2 |
Ki = 15.85 nM
|
|
|
|
CP0380240
|
1-benzyl-3-[4-(1H-imidazol-4-yl)butyl]thiourea
Show/Hide
|
C15H20N4S
|
1
|
| 1 |
EC50 = 79.43 nM
|
|
|
|
CP0877909
|
8-chloro-2-fluoro-11-(4-methylpiperazin-1-yl)-dibenzo[b,f][1,4]oxazepine
Show/Hide
|
C18H17ClFN3O
|
2
|
| 1 |
EC50 = 81.28 nM
|
|
|
| 2 |
Ki = 190.55 nM
|
|
|
|
CP0371150
|
4-(4-methylpiperazin-1-yl)-N-(2-methylpropyl)pyrimidin-2-amine
Show/Hide
|
C13H23N5
|
1
|
| 1 |
EC50 = 84 nM
|
|
|
|
CP0311383
|
6-(4-methylpiperazin-1-yl)-2-N-(2-methylpropyl)pyrimidine-2,4-diamine
Show/Hide
|
C13H24N6
|
1
|
| 1 |
EC50 = 86 nM
|
|
|
|
CP0130122
|
N-cyclopentyl-4-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine
Show/Hide
|
C14H23N5
|
1
|
| 1 |
EC50 = 86 nM
|
|
|
|
CP0386870
|
N-butyl-4-(4-methylpiperazin-1-yl)pyrimidin-2-amine
Show/Hide
|
C13H23N5
|
1
|
| 1 |
EC50 = 91 nM
|
|
|
|
CP0394508
|
(NZ)-N-[(5-methyl-1H-indol-2-yl)-(1-methylpiperidin-4-yl)methylidene]hydroxylamine
Show/Hide
|
C16H21N3O
|
2
|
| 1 |
EC50 = 100 nM
|
|
|
| 2 |
Ki = 50.12 nM
|
|
|
|
CP0380243
|
3-ethyl-1-[4-(1H-imidazol-4-yl)butyl]thiourea
Show/Hide
|
C10H18N4S
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0171841
|
4-N-cyclopentyl-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C14H24N6
|
1
|
| 1 |
EC50 = 101 nM
|
|
|
|
CP0886367
|
3,8-dichloro-11-(4-methylpiperazin-1-yl)-dibenzo[b,f][1,4]oxazepine
Show/Hide
|
C18H17Cl2N3O
|
2
|
| 1 |
EC50 = 102.33 nM
|
|
|
| 2 |
Ki = 309.03 nM
|
|
|
|
CP0897727
|
7-methyl-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepine
Show/Hide
|
C19H21N3O
|
2
|
| 1 |
EC50 = 104.71 nM
|
|
|
| 2 |
Ki = 79.43 nM
|
|
|
|
CP0371151
|
4-(4-methylpiperazin-1-yl)-N-propan-2-ylpyrimidin-2-amine
Show/Hide
|
C12H21N5
|
1
|
| 1 |
EC50 = 112 nM
|
|
|
|
CP0172969
|
5-[(2R,5S)-5-(phenylmethoxymethyl)oxolan-2-yl]-1H-imidazole
Show/Hide
|
C15H18N2O2
|
2
|
| 1 |
EC50 = 125.89 nM
|
|
|
| 2 |
EC50 = 134.9 nM
|
|
|
|
CP0221941
|
1-(3-(4-(5-fluoro-4-methyl-1H-benzo[d]imidazol-2-yl)-3-methylphenoxy)propyl)-N,N-dimethylpyrrolidin-3-amine
Show/Hide
|
C24H31FN4O
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0108024
|
3-(1H-imidazol-5-yl)propan-1-amine
Show/Hide
|
C6H11N3
|
2
|
| 1 |
EC50 = 199.53 nM
|
|
|
| 2 |
EC50 = 213.8 nM
|
|
|
|
CP0279022
|
1-cyano-3-[[(2S,5R)-5-(1H-imidazol-5-yl)oxolan-2-yl]methyl]-2-methylguanidine
Show/Hide
|
C11H16N6O
|
2
|
| 1 |
EC50 = 199.53 nM
|
|
|
| 2 |
EC50 = 223.87 nM
|
|
|
|
CP0076121
|
13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene
Show/Hide
|
C18H18ClN3O
|
2
|
| 1 |
EC50 = 218.78 nM
|
|
|
| 2 |
Ki = 4570.88 nM
|
|
|
|
CP0801066
|
11-(4-Methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepine
Show/Hide
|
C18H19N3O
|
2
|
| 1 |
EC50 = 302 nM
|
|
|
| 2 |
Ki = 131.83 nM
|
|
|
|
CP0305706
|
1-(3-(4-(5-fluoro-4-methyl-1H-benzo[d]imidazol-2-yl)-3-methylphenoxy)propyl)piperidin-3-amine
Show/Hide
|
C23H29FN4O
|
1
|
| 1 |
EC50 = 331 nM
|
|
|
|
CP0227942
|
5-[[(3R)-pyrrolidin-3-yl]methyl]-1H-imidazole
Show/Hide
|
C8H13N3
|
1
|
| 1 |
EC50 = 416.87 nM
|
|
|
|
CP0213376
|
1-(3-(4-(5-fluoro-4-methyl-1H-benzo[d]imidazol-2-yl)-3-methylphenoxy)propyl)pyrrolidin-3-amine
Show/Hide
|
C22H27FN4O
|
2
|
| 1 |
EC50 = 470 nM
|
|
|
| 2 |
Kd = 50.12 nM
|
|
|
|
CP0332122
|
4-(4-methylpiperazin-1-yl)-6-N-propan-2-ylpyridine-2,6-diamine
Show/Hide
|
C13H23N5
|
1
|
| 1 |
EC50 = 533 nM
|
|
|
|
CP0047136
|
(2R)-1-(1H-imidazol-5-yl)propan-2-amine
Show/Hide
|
C6H11N3
|
3
|
| 1 |
EC50 = 630.96 nM
|
|
|
| 2 |
EC50 = 1122.02 nM
|
|
|
| 3 |
Ki = 184 nM
|
|
|
|
CP0068025
|
(+/-)-5-fluoro-4-methyl-2-(2-methyl-4-(3-(3-methyl-3,6-diazabicyclo[3.1.0]hexan-6-yl)propoxy)phenyl)-1H-benzo[d]imidazole
Show/Hide
|
C23H27FN4O
|
2
|
| 1 |
EC50 = 710 nM
|
|
|
| 2 |
Kd = 66.07 nM
|
|
|
|
CP0099997
|
5-(pyrrolidin-3-ylmethyl)-1H-imidazole
Show/Hide
|
C8H13N3
|
1
|
| 1 |
EC50 = 741.31 nM
|
|
|
|
CP0348117
|
5-[(2R,5R)-5-(phenylmethoxymethyl)oxolan-2-yl]-1H-imidazole
Show/Hide
|
C15H18N2O2
|
2
|
| 1 |
EC50 = 741.31 nM
|
|
|
| 2 |
EC50 = 794.33 nM
|
|
|
|
CP0061272
|
N(alpha)-Methylhistamine
Show/Hide
|
C6H11N3
|
1
|
| 1 |
EC50 = 794.33 nM
|
|
|
|
CP0376332
|
4-(1H-imidazol-5-ylmethyl)pyridine
Show/Hide
|
C9H9N3
|
3
|
| 1 |
EC50 = 912.01 nM
|
|
|
| 2 |
EC50 = 1000 nM
|
|
|
| 3 |
Ki = 245.47 nM
|
|
|
|
CP0130186
|
N-(2-bicyclo[2.2.1]heptanyl)-5-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyridazin-3-amine
Show/Hide
|
C16H25N5
|
2
|
| 1 |
EC50 = 1000 nM
|
|
|
| 2 |
Kd = 10 nM
|
|
|
|
CP0220693
|
5-[[(3S)-pyrrolidin-3-yl]methyl]-1H-imidazole
Show/Hide
|
C8H13N3
|
1
|
| 1 |
EC50 = 1023.29 nM
|
|
|
|
CP0108124
|
[2-(1H-imidazol-5-yl)cyclopropyl]methanamine
Show/Hide
|
C7H11N3
|
1
|
| 1 |
EC50 = 1096.48 nM
|
|
|
|
CP0861251
|
3-[3-(3H-Imidazol-4-yl)-propyl]-pyridine
Show/Hide
|
C11H13N3
|
2
|
| 1 |
EC50 = 1258.93 nM
|
|
|
| 2 |
Ki = 478.63 nM
|
|
|
|
CP0437520
|
3-[4-(1H-imidazol-4-yl)butyl]-1-(2-phenylethyl)thiourea
Show/Hide
|
C16H22N4S
|
1
|
| 1 |
EC50 = 1258.93 nM
|
|
|
|
CP0846869
|
4-[2-(3H-Imidazol-4-yl)-ethyl]-pyridine
Show/Hide
|
C10H11N3
|
2
|
| 1 |
EC50 = 1513.56 nM
|
|
|
| 2 |
Ki = 1318.26 nM
|
|
|
|
CP0845651
|
4-[3-(3H-Imidazol-4-yl)-propyl]-pyridine
Show/Hide
|
C11H13N3
|
2
|
| 1 |
EC50 = 1548.82 nM
|
|
|
| 2 |
Ki = 1000 nM
|
|
|
|
CP0250505
|
3-(dimethylamino)propyl carbamimidothioate
Show/Hide
|
C6H15N3S
|
3
|
| 1 |
EC50 = 1584.89 nM
|
|
|
| 2 |
Ki = 90 nM
|
|
|
| 3 |
Ki = 316.23 nM
|
|
|
|
CP0130853
|
Imifuramine
Show/Hide
|
C8H13N3O
|
1
|
| 1 |
EC50 = 1995.26 nM
|
|
|
|
CP0050043
|
3-[2-(1H-imidazol-5-yl)ethyl]piperidine
Show/Hide
|
C10H17N3
|
1
|
| 1 |
EC50 = 2041.74 nM
|
|
|
|
CP0365453
|
5-[(3R)-3-(methylamino)pyrrolidin-1-yl]-N-(2-methylpropyl)pyridazin-3-amine
Show/Hide
|
C13H23N5
|
2
|
| 1 |
EC50 = 3160 nM
|
|
|
| 2 |
Kd = 15.85 nM
|
|
|
|
CP0090040
|
4-[(3R)-3-(methylamino)pyrrolidin-1-yl]-N-propan-2-ylpyridin-2-amine
Show/Hide
|
C13H22N4
|
2
|
| 1 |
EC50 = 3162 nM
|
|
|
| 2 |
Kd = 3.162 nM
|
|
|
|
CP0272050
|
N-(2-bicyclo[2.2.1]heptanyl)-4-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine
Show/Hide
|
C16H25N5
|
2
|
| 1 |
EC50 = 3162 nM
|
|
|
| 2 |
Kd = 0.07943 nM
|
|
|
|
CP0847382
|
2-[3-(3H-Imidazol-4-yl)-propyl]-pyridine
Show/Hide
|
C11H13N3
|
2
|
| 1 |
EC50 = 3162.28 nM
|
|
|
| 2 |
Ki = 1258.93 nM
|
|
|
|
CP0684017
|
3-((1H-imidazol-5-yl)methyl)piperidine
Show/Hide
|
C9H15N3
|
1
|
| 1 |
EC50 = 3981.07 nM
|
|
|
|
CP0182141
|
[(2S,5R)-5-(1H-imidazol-5-yl)oxolan-2-yl]methanamine
Show/Hide
|
C8H13N3O
|
2
|
| 1 |
EC50 = 5011.87 nM
|
|
|
| 2 |
EC50 = 5495.41 nM
|
|
|
|
CP0376707
|
4-(1H-imidazol-5-ylmethyl)-1-methylpiperidine
Show/Hide
|
C10H17N3
|
2
|
| 1 |
EC50 = 5011.87 nM
|
|
|
| 2 |
Ki = 1995.26 nM
|
|
|
|
CP0047517
|
(1S,2S)-2-(1H-Imidazol-4-yl)-cyclopropylamine
Show/Hide
|
C6H9N3
|
1
|
| 1 |
EC50 = 7079.46 nM
|
|
|
|
CP0097151
|
[(2R,5S)-5-(1H-imidazol-5-yl)oxolan-2-yl]methanamine
Show/Hide
|
C8H13N3O
|
2
|
| 1 |
EC50 = 7585.78 nM
|
|
|
| 2 |
EC50 = 7943.28 nM
|
|
|
|
CP0099909
|
1-cyano-3-[[(2R,5S)-5-(1H-imidazol-5-yl)oxolan-2-yl]methyl]-2-methylguanidine
Show/Hide
|
C11H16N6O
|
2
|
| 1 |
EC50 = 7585.78 nM
|
|
|
| 2 |
EC50 = 7943.28 nM
|
|
|
|
CP0213377
|
(+/-)-5-fluoro-2-(4-(3-(hexahydropyrrolo[3,4-b]pyrrol-5(1H)-yl)propoxy)-2-methylphenyl)-4-methyl-1H-benzo[d]imidazole
Show/Hide
|
C24H29FN4O
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 12.59 nM
|
|
|
|
CP0221946
|
(+/-)-5-fluoro-4-methyl-2-(2-methyl-4-(3-(6-methyl-3,6-diazabicyclo[3.1.0]hexan-3-yl)propoxy)phenyl)-1H-benzo[d]imidazole
Show/Hide
|
C23H27FN4O
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 158.49 nM
|
|
|
|
CP0274705
|
(+/-)-5-fluoro-4-methyl-2-(2-methyl-4-(3-(tetrahydro-1H-pyrrolo[3,4-b]pyridin-6(2H,7H,7aH)-yl)propoxy)phenyl)-1H-benzo[d]imidazole
Show/Hide
|
C25H31FN4O
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 50.12 nM
|
|
|
|
CP0288244
|
5-fluoro-4-methyl-2-(2-methyl-4-(3-((4aR,7aR)-tetrahydro-1H-pyrrolo[3,4-b]pyridin-6(2H,7H,7aH)-yl)propoxy)phenyl)-1H-benzo[d]imidazole
Show/Hide
|
C25H31FN4O
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 25.12 nM
|
|
|
|
CP0171496
|
(R)-N2-cyclopentyl-6-(3-(methylamino)pyrrolidin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C14H24N6
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 12.59 nM
|
|
|
|
CP0171499
|
(R)-4-(3-(methylamino)pyrrolidin-1-yl)-6-(pyrrolidin-1-yl)pyridin-2-amine
Show/Hide
|
C14H23N5
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 15.85 nM
|
|
|
|
CP0171840
|
4-(4-Methylpiperazin-1-yl)-6-pyrrolidin-1-ylpyrimidin-2-ylamine
Show/Hide
|
C13H22N6
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 1.995 nM
|
|
|
|
CP0207351
|
6-(4-methylpiperazin-1-yl)-4-N-(2-methylpropyl)pyrimidine-2,4-diamine
Show/Hide
|
C13H24N6
|
3
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 1.259 nM
|
|
|
| 3 |
Ki = 3.162 nM
|
|
|
|
CP0207352
|
(R)-N4-isobutyl-6-(3-(methylamino)pyrrolidin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C13H24N6
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 0.5012 nM
|
|
|
|
CP0242759
|
(R)-N2-isobutyl-4-(3-(methylamino)pyrrolidin-1-yl)pyridine-2,6-diamine
Show/Hide
|
C14H25N5
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 1.585 nM
|
|
|
|
CP0257100
|
(R)-N4-isopropyl-6-(3-(methylamino)pyrrolidin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C12H22N6
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 10 nM
|
|
|
|
CP0257102
|
(R)-N4-cyclopentyl-6-(3-(methylamino)pyrrolidin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C14H24N6
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 0.3981 nM
|
|
|
|
CP0282159
|
(R)-N2-cyclopentyl-4-(3-(methylamino)pyrrolidin-1-yl)pyridine-2,6-diamine
Show/Hide
|
C15H25N5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0292387
|
(R)-N2-isobutyl-6-(3-(methylamino)pyrrolidin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C13H24N6
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 1.585 nM
|
|
|
|
CP0292394
|
4-(piperazin-1-yl)-6-(pyrrolidin-1-yl)pyrimidin-2-amine
Show/Hide
|
C12H20N6
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0296515
|
(R)-N2-isopropyl-6-(3-(methylamino)pyrrolidin-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C12H22N6
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 12.59 nM
|
|
|
|
CP0332121
|
4-N-methyl-6-(4-methylpiperazin-1-yl)-4-N-propan-2-ylpyrimidine-2,4-diamine
Show/Hide
|
C13H24N6
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0337586
|
(R)-4-(3-(methylamino)pyrrolidin-1-yl)-6-(pyrrolidin-1-yl)pyrimidin-2-amine
Show/Hide
|
C13H22N6
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 7.943 nM
|
|
|
|
CP0337591
|
(R)-N2-isopropyl-4-(3-(methylamino)pyrrolidin-1-yl)pyridine-2,6-diamine
Show/Hide
|
C13H23N5
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 1.585 nM
|
|
|
|
CP0346013
|
4-(4-methylpiperazin-1-yl)-6-(pyrrolidin-1-yl)pyridin-2-amine
Show/Hide
|
C14H23N5
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 19.95 nM
|
|
|
|
CP0052696
|
N-cyclopentyl-4-[(3S)-3-(methylamino)pyrrolidin-1-yl]pyridin-2-amine
Show/Hide
|
C15H24N4
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 39.81 nM
|
|
|
|
CP0089118
|
N-cyclopentyl-4-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyridin-2-amine
Show/Hide
|
C15H24N4
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 1 nM
|
|
|
|
CP0119547
|
N-(2-bicyclo[2.2.1]heptanyl)-4-[(3S)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine
Show/Hide
|
C16H25N5
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 7.943 nM
|
|
|
|
CP0130185
|
N-(2-bicyclo[2.2.1]heptanyl)-5-[(3S)-3-(methylamino)pyrrolidin-1-yl]pyridazin-3-amine
Show/Hide
|
C16H25N5
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 7.943 nM
|
|
|
|
CP0386871
|
N-(2-bicyclo[2.2.1]heptanyl)-4-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyridin-2-amine
Show/Hide
|
C17H26N4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0398277
|
N-(2-bicyclo[2.2.1]heptanyl)-4-[(3S)-3-(methylamino)pyrrolidin-1-yl]pyridin-2-amine
Show/Hide
|
C17H26N4
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 1 nM
|
|
|
|
CP0441099
|
2-((1H-imidazol-4-yl)methyl)pyridine
Show/Hide
|
C9H9N3
|
2
|
| 1 |
EC50 = 10471.29 nM
|
|
|
| 2 |
Ki = 4570.88 nM
|
|
|
|
CP0122622
|
5-[(2S,5R)-5-(phenylmethoxymethyl)oxolan-2-yl]-1H-imidazole
Show/Hide
|
C15H18N2O2
|
2
|
| 1 |
EC50 = 11481.54 nM
|
|
|
| 2 |
EC50 = 12589.25 nM
|
|
|
|
CP0309840
|
5-[(2S,5S)-5-(phenylmethoxymethyl)oxolan-2-yl]-1H-imidazole
Show/Hide
|
C15H18N2O2
|
2
|
| 1 |
EC50 = 12589.25 nM
|
|
|
| 2 |
EC50 = 12882.5 nM
|
|
|
|
CP0376706
|
(2S)-1-(1H-imidazol-5-yl)propan-2-amine
Show/Hide
|
C6H11N3
|
1
|
| 1 |
EC50 = 12589.25 nM
|
|
|
|
CP0380345
|
3-((1H-imidazol-4-yl)methyl)pyridine
Show/Hide
|
C9H9N3
|
2
|
| 1 |
EC50 = 15135.61 nM
|
|
|
| 2 |
Ki = 691.83 nM
|
|
|
|
CP0195654
|
1-cyano-3-[[(2S,5S)-5-(1H-imidazol-5-yl)oxolan-2-yl]methyl]-2-methylguanidine
Show/Hide
|
C11H16N6O
|
2
|
| 1 |
EC50 = 19952.62 nM
|
|
|
| 2 |
EC50 = 21379.62 nM
|
|
|
|
CP0154225
|
[(2R,5R)-5-(1H-imidazol-5-yl)-2,5-dihydrofuran-2-yl]methanamine
Show/Hide
|
C8H11N3O
|
1
|
| 1 |
EC50 = 23988.33 nM
|
|
|
|
CP0154610
|
[(2S,5S)-5-(1H-imidazol-5-yl)oxolan-2-yl]methanamine
Show/Hide
|
C8H13N3O
|
2
|
| 1 |
EC50 = 30902.95 nM
|
|
|
| 2 |
EC50 = 31622.78 nM
|
|
|
|
CP0860906
|
3-[2-(3H-Imidazol-4-yl)-ethyl]-pyridine
Show/Hide
|
C10H11N3
|
2
|
| 1 |
EC50 = 32359.37 nM
|
|
|
| 2 |
Ki = 5128.61 nM
|
|
|
|
CP0055652
|
[(2S,5R)-5-(1H-imidazol-5-yl)-2,5-dihydrofuran-2-yl]methanamine
Show/Hide
|
C8H11N3O
|
1
|
| 1 |
EC50 = 40738.03 nM
|
|
|
|
CP0845085
|
2-[2-(3H-Imidazol-4-yl)-ethyl]-pyridine
Show/Hide
|
C10H11N3
|
2
|
| 1 |
EC50 = 58884.37 nM
|
|
|
| 2 |
Ki = 12302.69 nM
|
|
|
|
CP0038430
|
[(2R,5S)-5-(1H-imidazol-5-yl)-2,5-dihydrofuran-2-yl]methanamine
Show/Hide
|
C8H11N3O
|
1
|
| 1 |
EC50 = 75857.76 nM
|
|
|
|
CP0100889
|
[(2S,5S)-5-(1H-imidazol-5-yl)-2,5-dihydrofuran-2-yl]methanamine
Show/Hide
|
C8H11N3O
|
1
|
| 1 |
EC50 = 85113.8 nM
|
|
|
|
CP0037936
|
6-(1H-imidazol-5-yl)hexan-1-amine
Show/Hide
|
C9H17N3
|
1
|
| 1 |
EC50 < 10000 nM
|
|
|
|
CP0049208
|
2-[2-(1H-imidazol-5-yl)ethyl]piperidine
Show/Hide
|
C10H17N3
|
1
|
| 1 |
EC50 < 10000 nM
|
|
|
|
CP0049414
|
4-[1-(1H-imidazol-5-yl)ethenyl]piperidine
Show/Hide
|
C10H15N3
|
1
|
| 1 |
EC50 < 10000 nM
|
|
|
|
CP0049822
|
4-[3-(1H-imidazol-5-yl)propyl]piperidine
Show/Hide
|
C11H19N3
|
1
|
| 1 |
EC50 < 10000 nM
|
|
|
|
CP0114981
|
(1R,2R)-2-(1H-Imidazol-4-yl)-cyclopropylamine
Show/Hide
|
C6H9N3
|
1
|
| 1 |
EC50 < 10000 nM
|
|
|
|
CP0185528
|
3-[3-(1H-imidazol-5-yl)propyl]piperidine
Show/Hide
|
C11H19N3
|
1
|
| 1 |
EC50 < 10000 nM
|
|
|
|
CP0197119
|
4-(1H-imidazol-5-yl)-1,2,3,6-tetrahydropyridine
Show/Hide
|
C8H11N3
|
1
|
| 1 |
EC50 < 10000 nM
|
|
|
|
CP0207500
|
4-(1H-imidazol-5-ylmethylidene)piperidine
Show/Hide
|
C9H13N3
|
1
|
| 1 |
EC50 < 10000 nM
|
|
|
|
CP0208579
|
4( 5)-( 5-aminopenty1)-lH-imidazole
Show/Hide
|
C8H15N3
|
2
|
| 1 |
EC50 < 10000 nM
|
|
|
| 2 |
Ki = 251.19 nM
|
|
|
|
CP0208773
|
2-[3-(1H-imidazol-5-yl)propyl]piperidine
Show/Hide
|
C11H19N3
|
1
|
| 1 |
EC50 < 10000 nM
|
|
|
|
CP0212820
|
2-(1H-imidazol-5-ylmethyl)piperidine
Show/Hide
|
C9H15N3
|
1
|
| 1 |
EC50 < 10000 nM
|
|
|
|
CP0216996
|
4-[2-(1H-imidazol-5-yl)ethyl]piperidine
Show/Hide
|
C10H17N3
|
1
|
| 1 |
EC50 < 10000 nM
|
|
|
|
CP0220690
|
1H-imidazol-5-yl(piperidin-4-yl)methanone
Show/Hide
|
C9H13N3O
|
1
|
| 1 |
EC50 < 10000 nM
|
|
|
|
CP0244327
|
4-(1H-imidazol-5-yl)piperidine
Show/Hide
|
C8H13N3
|
1
|
| 1 |
EC50 < 10000 nM
|
|
|
|
CP0060466
|
4-(1-adamantyl)-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine
Show/Hide
|
C19H29N5
|
2
|
| 1 |
Kd < 0.1 nM
|
|
|
| 2 |
Ki = 1.7 nM
|
|
|
|
CP0115846
|
4-[(4aR,7aR)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl]-6-cyclopentylpyrimidin-2-amine
Show/Hide
|
C16H25N5
|
2
|
| 1 |
Kd < 0.1 nM
|
|
|
| 2 |
Ki = 1.8 nM
|
|
|
|
CP0251187
|
4-[(3aR,6aR)-2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[2,3-c]pyrrol-5-yl]-6-cyclopentylpyrimidin-2-amine
Show/Hide
|
C15H23N5
|
2
|
| 1 |
Kd = 0.1 nM
|
|
|
| 2 |
Ki = 2.9 nM
|
|
|
|
CP0361356
|
4-cyclohexyl-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine
Show/Hide
|
C15H25N5
|
2
|
| 1 |
Kd < 0.1 nM
|
|
|
| 2 |
Ki = 2.3 nM
|
|
|
|
CP0173430
|
4-cyclopentyl-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine
Show/Hide
|
C14H23N5
|
2
|
| 1 |
Kd = 0.1259 nM
|
|
|
| 2 |
Ki = 1.4 nM
|
|
|
|
CP0340876
|
4-cyclopentyl-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine
Show/Hide
|
C14H23N5
|
2
|
| 1 |
Kd = 0.2512 nM
|
|
|
| 2 |
Ki = 1.1 nM
|
|
|
|
CP0129069
|
4-cyclopentyl-6-piperazin-1-ylpyrimidin-2-amine
Show/Hide
|
C13H21N5
|
2
|
| 1 |
Kd = 0.3162 nM
|
|
|
| 2 |
Ki = 1.2 nM
|
|
|
|
CP0480123
|
4-cyclobutyl-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine
Show/Hide
|
C13H21N5
|
2
|
| 1 |
Kd = 0.3981 nM
|
|
|
| 2 |
Ki = 2.4 nM
|
|
|
|
CP0382706
|
4-[(3R)-3-aminopyrrolidin-1-yl]-6-cyclopentylpyrimidin-2-amine
Show/Hide
|
C13H21N5
|
2
|
| 1 |
Kd = 0.631 nM
|
|
|
| 2 |
Ki = 0.92 nM
|
|
|
|
CP0116623
|
4-[(3R)-3-(methylamino)pyrrolidin-1-yl]-N-(2-methylpropyl)pyridin-2-amine
Show/Hide
|
C14H24N4
|
1
|
| 1 |
Kd = 0.631 nM
|
|
|
|
CP0340877
|
4-tert-butyl-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine
Show/Hide
|
C13H23N5
|
2
|
| 1 |
Kd = 2.512 nM
|
|
|
| 2 |
Ki = 8 nM
|
|
|
|
CP0361322
|
4-cyclopentyl-6-(1,7-diazaspiro[4.4]nonan-7-yl)pyrimidin-2-amine
Show/Hide
|
C16H25N5
|
2
|
| 1 |
Kd = 2.512 nM
|
|
|
| 2 |
Ki = 11.2 nM
|
|
|
|
CP0536915
|
4-butyl-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine
Show/Hide
|
C13H23N5
|
2
|
| 1 |
Kd = 3.981 nM
|
|
|
| 2 |
Ki = 1.5 nM
|
|
|
|
CP0361357
|
4-[(3R)-3-aminopyrrolidin-1-yl]-6-tert-butylpyrimidin-2-amine
Show/Hide
|
C12H21N5
|
2
|
| 1 |
Kd = 5.012 nM
|
|
|
| 2 |
Ki = 9.4 nM
|
|
|
|
CP0233670
|
(4,5-Dichloro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H15Cl2N3O
|
2
|
| 1 |
Kd = 6.31 nM
|
|
|
| 2 |
Ki = 5 nM
|
|
|
|
CP0041262
|
5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-indole
Show/Hide
|
C14H16ClN3O
|
9
|
| 1 |
Kd = 7.943 nM
|
|
|
| 2 |
Ki = 4 nM
|
|
|
| 3 |
Ki = 5 nM
|
|
|
| 4 |
Ki = 6.31 nM
|
|
|
| 5 |
Ki = 13 nM
|
|
|
| 6 |
Ki = 15.85 nM
|
|
|
| 7 |
Ki = 17 nM
|
|
|
| 8 |
Ki = 19.95 nM
|
|
|
| 9 |
Ki = 63.1 nM
|
|
|
|
CP0160979
|
(7-Amino-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H18N4O
|
2
|
| 1 |
Kd = 7.943 nM
|
|
|
| 2 |
Ki = 8 nM
|
|
|
|
CP0231594
|
(5-Amino-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H18N4O
|
2
|
| 1 |
Kd = 7.943 nM
|
|
|
| 2 |
Ki = 15 nM
|
|
|
|
CP0368406
|
4-cyclopropyl-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine
Show/Hide
|
C12H19N5
|
2
|
| 1 |
Kd = 7.943 nM
|
|
|
| 2 |
Ki = 28 nM
|
|
|
|
CP0114131
|
(5,7-Dichloro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H15Cl2N3O
|
2
|
| 1 |
Kd = 10 nM
|
|
|
| 2 |
Ki = 11 nM
|
|
|
|
CP0115847
|
(3S,4S)-1-(2-amino-6-cyclopentylpyrimidin-4-yl)-4-(methylamino)pyrrolidin-3-ol
Show/Hide
|
C14H23N5O
|
2
|
| 1 |
Kd = 10 nM
|
|
|
| 2 |
Ki = 30 nM
|
|
|
|
CP0247768
|
4-ethyl-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine
Show/Hide
|
C11H19N5
|
2
|
| 1 |
Kd = 10 nM
|
|
|
| 2 |
Ki = 21 nM
|
|
|
|
CP0361354
|
4-benzyl-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine
Show/Hide
|
C16H21N5
|
2
|
| 1 |
Kd = 10 nM
|
|
|
| 2 |
Ki = 36 nM
|
|
|
|
CP0054275
|
N-cyclopentyl-5-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyridazin-3-amine
Show/Hide
|
C14H23N5
|
1
|
| 1 |
Kd = 10 nM
|
|
|
|
CP0025667
|
2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone
Show/Hide
|
C18H19ClN4
|
5
|
| 1 |
Kd = 11.9 nM
|
|
|
| 2 |
Kd = 14.5 nM
|
|
|
| 3 |
Kd = 20.9 nM
|
|
|
| 4 |
Kd = 70.2 nM
|
|
|
| 5 |
Ki = 177.83 nM
|
|
|
|
CP0498531
|
(2-chloro-6H-thieno[2,3-b]pyrrol-5-yl)(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C12H14ClN3OS
|
2
|
| 1 |
Kd = 12.59 nM
|
|
|
| 2 |
Ki = 25 nM
|
|
|
|
CP0058845
|
4-[(3R)-3-aminopyrrolidin-1-yl]-6-propan-2-ylpyrimidin-2-amine
Show/Hide
|
C11H19N5
|
2
|
| 1 |
Kd = 12.59 nM
|
|
|
| 2 |
Ki = 12.5 nM
|
|
|
|
CP0369772
|
4-[(3R)-3-(methylamino)pyrrolidin-1-yl]-6-propan-2-ylpyrimidin-2-amine
Show/Hide
|
C12H21N5
|
2
|
| 1 |
Kd = 12.59 nM
|
|
|
| 2 |
Ki = 12 nM
|
|
|
|
CP0510462
|
4-[(3R)-3-aminopyrrolidin-1-yl]-6-ethylpyrimidin-2-amine
Show/Hide
|
C10H17N5
|
2
|
| 1 |
Kd = 12.59 nM
|
|
|
| 2 |
Ki = 21 nM
|
|
|
|
CP0193887
|
(5-Bromo-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H16BrN3O
|
3
|
| 1 |
Kd = 15.85 nM
|
|
|
| 2 |
Ki = 8 nM
|
|
|
| 3 |
Ki = 31.62 nM
|
|
|
|
CP0469416
|
(5-fluoro-4-methyl-1H-benzoimidazol-2-yl)(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C14H17FN4O
|
2
|
| 1 |
Kd = 15.85 nM
|
|
|
| 2 |
Ki = 7 nM
|
|
|
|
CP0066043
|
(5-Chloro-1H-benzoimidazol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C13H15ClN4O
|
4
|
| 1 |
Kd = 19.95 nM
|
|
|
| 2 |
Ki = 20 nM
|
|
|
| 3 |
Ki = 26 nM
|
|
|
| 4 |
Ki = 79.43 nM
|
|
|
|
CP0071086
|
(5-Fluoro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H16FN3O
|
2
|
| 1 |
Kd = 19.95 nM
|
|
|
| 2 |
Ki = 15 nM
|
|
|
|
CP0071088
|
(5,7-Difluoro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H15F2N3O
|
2
|
| 1 |
Kd = 19.95 nM
|
|
|
| 2 |
Ki = 14 nM
|
|
|
|
CP0071089
|
(5-methyl-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C15H19N3O
|
2
|
| 1 |
Kd = 19.95 nM
|
|
|
| 2 |
Ki = 46 nM
|
|
|
|
CP0485649
|
(2-chloro-3-methyl-4H-thieno[3,2-b]pyrrol-5-yl)(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C13H16ClN3OS
|
2
|
| 1 |
Kd = 19.95 nM
|
|
|
| 2 |
Ki = 3 nM
|
|
|
|
CP0496817
|
(5-fluoro-4-methyl-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C15H18FN3O
|
2
|
| 1 |
Kd = 19.95 nM
|
|
|
| 2 |
Ki = 27 nM
|
|
|
|
CP0875064
|
2-[3-(Imidazol-4-yl)-propyl]-1-(benzyl)-isothioureadihydrobromide
Show/Hide
|
C14H20Br2N4S
|
2
|
| 1 |
Kd = 19.95 nM
|
|
|
| 2 |
Ki = 25.12 nM
|
|
|
|
CP0382709
|
4-[(3aR,6aS)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-6-cyclopentylpyrimidin-2-amine
Show/Hide
|
C16H25N5
|
2
|
| 1 |
Kd = 19.95 nM
|
|
|
| 2 |
Ki = 25 nM
|
|
|
|
CP0469414
|
(4-methyl-1H-benzoimidazol-2-yl)(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C14H18N4O
|
2
|
| 1 |
Kd = 25.12 nM
|
|
|
| 2 |
Ki = 30 nM
|
|
|
|
CP0361321
|
4-(3-aminoazetidin-1-yl)-6-cyclopentylpyrimidin-2-amine
Show/Hide
|
C12H19N5
|
2
|
| 1 |
Kd = 25.12 nM
|
|
|
| 2 |
Ki = 5.5 nM
|
|
|
|
CP0541017
|
4-[(3R)-3-(methylamino)pyrrolidin-1-yl]-5,6,7,8-tetrahydroquinazolin-2-amine
Show/Hide
|
C13H21N5
|
2
|
| 1 |
Kd = 25.12 nM
|
|
|
| 2 |
Ki = 43 nM
|
|
|
|
CP0114128
|
(5,7-Dimethyl-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C16H21N3O
|
2
|
| 1 |
Kd = 31.62 nM
|
|
|
| 2 |
Ki = 31 nM
|
|
|
|
CP0515667
|
(4-methylpiperazin-1-yl)-(3-methyl-4H-thieno[3,2-b]pyrrol-5-yl)-methanone
Show/Hide
|
C13H17N3OS
|
2
|
| 1 |
Kd = 31.62 nM
|
|
|
| 2 |
Ki = 21 nM
|
|
|
|
CP0249606
|
(1H-Indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H17N3O
|
3
|
| 1 |
Kd = 39.81 nM
|
|
|
| 2 |
Ki = 17 nM
|
|
|
| 3 |
Ki = 25.12 nM
|
|
|
|
CP0403460
|
(5-fluoro-1H-benzoimidazol-2-yl)(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C13H15FN4O
|
2
|
| 1 |
Kd = 50.12 nM
|
|
|
| 2 |
Ki = 19 nM
|
|
|
|
CP0441847
|
(7-chloro-5-methyl-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C15H18ClN3O
|
2
|
| 1 |
Kd = 50.12 nM
|
|
|
| 2 |
Ki = 33 nM
|
|
|
|
CP0510339
|
(2-chloro-4H-thieno[3,2-b]pyrrol-5-yl)(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C12H14ClN3OS
|
2
|
| 1 |
Kd = 50.12 nM
|
|
|
| 2 |
Ki = 40 nM
|
|
|
|
CP0459484
|
(1H-benzoimidazol-2-yl)(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C13H16N4O
|
2
|
| 1 |
Kd = 63.1 nM
|
|
|
| 2 |
Ki = 35 nM
|
|
|
|
CP0071085
|
(5-Hydroxy-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H17N3O2
|
2
|
| 1 |
Kd = 79.43 nM
|
|
|
| 2 |
Ki = 23 nM
|
|
|
|
CP0114129
|
(7-Chloro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H16ClN3O
|
2
|
| 1 |
Kd = 79.43 nM
|
|
|
| 2 |
Ki = 19 nM
|
|
|
|
CP0510340
|
(4,5-difluoro-1H-benzoimidazol-2-yl)(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C13H14F2N4O
|
2
|
| 1 |
Kd = 79.43 nM
|
|
|
| 2 |
Ki = 49 nM
|
|
|
|
CP0071087
|
(7-Bromo-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H16BrN3O
|
2
|
| 1 |
Kd = 125.89 nM
|
|
|
| 2 |
Ki = 61 nM
|
|
|
|
CP0469417
|
(4-chloro-6-methyl-1H-benzoimidazol-2-yl)(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C14H17ClN4O
|
2
|
| 1 |
Kd = 125.89 nM
|
|
|
| 2 |
Ki = 23 nM
|
|
|
|
CP0316739
|
4-[(4aR,7aR)-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b][1,4]oxazin-6-yl]-6-cyclopentylpyrimidin-2-amine
Show/Hide
|
C15H23N5O
|
2
|
| 1 |
Kd = 125.89 nM
|
|
|
| 2 |
Ki = 56 nM
|
|
|
|
CP0037128
|
(4-Bromo-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H16BrN3O
|
2
|
| 1 |
Kd = 158.49 nM
|
|
|
| 2 |
Ki = 32 nM
|
|
|
|
CP0491739
|
2-arylbenzimidazole derivative, 10
Show/Hide
|
C24H31ClN4O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0852004
|
2-[3-(Imidazol-4-yl)-propyl]-1-(3,4-dichloro-benzyl)-isothiourea dihydrobromide
Show/Hide
|
C14H18Br2Cl2N4S
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0383812
|
4-(4-chlorophenyl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine
Show/Hide
|
C15H18ClN5
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0499695
|
4-(3-methylbutyl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine
Show/Hide
|
C14H25N5
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0041493
|
Clobenpropit
Show/Hide
|
C14H17ClN4S
|
3
|
| 1 |
Ki = 5 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
| 3 |
Ki = 50.12 nM
|
|
|
|
CP0128727
|
8-chloro-4-(4-methylpiperazin-1-yl)benzofuro[3,2-d]pyrimidine
Show/Hide
|
C15H15ClN4O
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0540278
|
5-fluoro-4-methyl-2-[5-methyl-2-[4-(1-methylpiperidin-4-yl)butoxy]pyridin-4-yl]-1H-benzimidazole
Show/Hide
|
C24H31FN4O
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0527631
|
4-N-[2-[(2-aminopyrimidin-4-yl)amino]ethyl]-6-(3-chlorophenyl)pyrimidine-2,4-diamine
Show/Hide
|
C16H17ClN8
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0114132
|
(7-Methyl-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C15H19N3O
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0297628
|
3-(1H-imidazol-5-yl)propyl N'-[2-(4-iodophenyl)ethyl]carbamimidothioate
Show/Hide
|
C15H19IN4S
|
2
|
| 1 |
Ki = 7.8 nM
|
|
|
| 2 |
Ki = 16 nM
|
|
|
|
CP0259827
|
4-(4-methylpiperazin-1-yl)-6-phenylpyrimidin-2-amine
Show/Hide
|
C15H19N5
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0556349
|
4-N-[2-[(2-aminopyrimidin-4-yl)amino]ethyl]-6-phenylpyrimidine-2,4-diamine
Show/Hide
|
C16H18N8
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0405799
|
2-arylbenzimidazole derivative, 9
Show/Hide
|
C24H31ClN4O
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0163641
|
12-chloro-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]-8-oxa-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-4-amine
Show/Hide
|
C14H15ClN6O
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0847507
|
2-[3-(Imidazol-4-yl)-propyl]-1-(4-iodo-benzyl)-isothiourea dihydrobromide
Show/Hide
|
C14H19Br2IN4S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0857599
|
2-[3-(Imidazol-4-yl)-propyl]-1-(2-chloro-benzyl)-isothiourea dihydrobromide
Show/Hide
|
C14H19Br2ClN4S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0902071
|
2-[3-(Imidazol-4-yl)-propyl]-1-(4-bromo-benzyl)-isothiourea dihydrobromide
Show/Hide
|
C14H18Br2N4S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0482542
|
4-N-[2-[(2-aminopyrimidin-4-yl)amino]ethyl]-4-N-methyl-6-phenylpyrimidine-2,4-diamine
Show/Hide
|
C17H20N8
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0524066
|
4-N-[2-[(2-aminopyrimidin-4-yl)amino]ethyl]-4-N-methyl-6-(3-methylbutyl)pyrimidine-2,4-diamine
Show/Hide
|
C16H26N8
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0857594
|
2-[3-(Imidazol-4-yl)-propyl]-1-(4-methoxy-benzyl)-isothiourea dihydrobromide
Show/Hide
|
C15H22Br2N4OS
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0879917
|
2-[3-(Imidazol-4-yl)-propyl]-1-(3-chloro-benzyl)-isothiourea dihydrobromide
Show/Hide
|
C14H19Br2ClN4S
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0902072
|
IODOPHENPROPIT
Show/Hide
|
C15H21Br2IN4S
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0862308
|
4-chloro-benzyl-[4-(1H-imidazol-4-yl)-butyl]-amine
Show/Hide
|
C14H18ClN3
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0554308
|
(4-methylpiperazin-1-yl)-(4,5,6,7-tetrahydro-1H-indol-2-yl)methanone
Show/Hide
|
C14H21N3O
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0559586
|
2-arylbenzimidazole derivative, 2
Show/Hide
|
C23H29ClN4O
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0244888
|
4-cyclopentyl-6-[(3S)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine
Show/Hide
|
C14H23N5
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0431202
|
2-benzyl-1-[3-(1H-imidazol-5-yl)propyl]guanidine
Show/Hide
|
C14H19N5
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0858273
|
2-[3-(Imidazol-4-yl)-propyl]-1-(3,3-diphenylpropyl)-isothiourea dihydrobromide
Show/Hide
|
C22H28Br2N4S
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0875065
|
2-[3-(Imidazol-4-yl)-propyl]-1-(4-fluoro-benzyl)-isothiourea dihydrobromide
Show/Hide
|
C14H19Br2FN4S
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0913221
|
2-[3-(Imidazol-4-yl)-propyl]-1-(4-methyl-benzyl)-isothiourea dihydrobromide
Show/Hide
|
C15H22Br2N4S
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0468257
|
4-N-[2-[(2-aminopyrimidin-4-yl)amino]ethyl]-6-(3-methylbutyl)pyrimidine-2,4-diamine
Show/Hide
|
C15H24N8
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0224450
|
2-arylbenzimidazole derivative, 6
Show/Hide
|
C26H35ClN4O
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0468053
|
2-arylbenzimidazole derivative, 8
Show/Hide
|
C26H36N4O
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0372558
|
2-arylbenzimidazole derivative, 4
Show/Hide
|
C25H27ClN4O
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0870385
|
2-[3-(Imidazol-4-yl)-propyl]-1-[2-(4-chloro-phenyl)-ethyl]-isothiourea dihydrobromide
Show/Hide
|
C15H21Br2ClN4S
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0527524
|
4-N-methyl-4-N-[2-[[2-(2-methylpropylamino)pyrimidin-4-yl]amino]ethyl]-6-phenylpyrimidine-2,4-diamine
Show/Hide
|
C21H28N8
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0361319
|
4-[(3S)-3-aminopyrrolidin-1-yl]-6-cyclopentylpyrimidin-2-amine
Show/Hide
|
C13H21N5
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0308219
|
(1H-Indol-2-yl)-piperazin-1-yl-methanone
Show/Hide
|
C13H15N3O
|
1
|
| 1 |
Ki = 38 nM
|
|
|
|
CP0382092
|
(4-methylpiperazin-1-yl)-(4,5,6,7-tetrahydro-1H-benzimidazol-2-yl)methanone
Show/Hide
|
C13H20N4O
|
1
|
| 1 |
Ki = 39 nM
|
|
|
|
CP0432714
|
VUF4903
Show/Hide
|
C14H25N3
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0854867
|
cyclopentyl-[4-(1H-imidazol-4-yl)-butyl]-amine
Show/Hide
|
C12H21N3
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0854868
|
cyclopentyl-[5-(1H-imidazol-4-yl)-pentyl]-amine
Show/Hide
|
C13H23N3
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0439526
|
3-(1H-imidazol-5-yl)propyl N'-[2-(4-bromophenyl)ethyl]carbamimidothioate
Show/Hide
|
C15H19BrN4S
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0456152
|
4-N-[2-[(2-aminopyrimidin-4-yl)amino]ethyl]-4-N-methyl-6-N-(2-methylpropyl)pyrimidine-2,4,6-triamine
Show/Hide
|
C15H25N9
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0510008
|
4-N-[2-[(2-methylpyrimidin-4-yl)amino]ethyl]-6-phenylpyrimidine-2,4-diamine
Show/Hide
|
C17H19N7
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0554286
|
2-arylbenzimidazole derivative, 1
Show/Hide
|
C23H29ClN4O
|
1
|
| 1 |
Ki = 46 nM
|
|
|
|
CP0393912
|
N-[5-(1H-imidazol-5-yl)pentyl]cycloheptanamine
Show/Hide
|
C15H27N3
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0849120
|
cycloheptyl-[4-(1H-imidazol-4-yl)-butyl]-amine
Show/Hide
|
C14H25N3
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0889371
|
[4-(1H-Imidazol-4-yl)butyl]propylamine
Show/Hide
|
C10H19N3
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0879916
|
2-[3-(Imidazol-4-yl)-propyl]-1-[3-(phenyl)-propyl]-isothiourea dihydrobromide
Show/Hide
|
C16H24Br2N4S
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0505481
|
(NZ)-N-[1H-indol-2-yl-(1-methylpiperidin-4-yl)methylidene]hydroxylamine
Show/Hide
|
C15H19N3O
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0524067
|
6-(3-chlorophenyl)-4-N-[2-[[2-(2-methylpropylamino)pyrimidin-4-yl]amino]ethyl]pyrimidine-2,4-diamine
Show/Hide
|
C20H25ClN8
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0525310
|
6-(3-chlorophenyl)-4-N-methyl-4-N-[2-[[2-(2-methylpropylamino)pyrimidin-4-yl]amino]ethyl]pyrimidine-2,4-diamine
Show/Hide
|
C21H27ClN8
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0779431
|
(5-Iodo-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H16IN3O
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0424833
|
VUF5202
Show/Hide
|
C15H20ClN3
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0875455
|
tert-butyl-[5-(1H-imidazol-4-yl)-pentyl]-amine
Show/Hide
|
C12H23N3
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0881153
|
butyl-[4-(1H-imidazol-4-yl)-butyl]-amine
Show/Hide
|
C11H21N3
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0377713
|
3-(1H-imidazol-5-yl)propyl N'-(4-phenylbutyl)carbamimidothioate
Show/Hide
|
C17H24N4S
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0870384
|
2-[3-(Imidazol-4-yl)-propyl]-1-[2-(phenyl)-ethyl]-isothiourea dihydrobromide
Show/Hide
|
C15H22Br2N4S
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0823737
|
SID50106398
Show/Hide
|
C5H11Cl2N3
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0316391
|
2-arylbenzimidazole derivative, 7
Show/Hide
|
C25H33ClN4O
|
1
|
| 1 |
Ki = 65 nM
|
|
|
|
CP0316741
|
4-methyl-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine
Show/Hide
|
C10H17N5
|
1
|
| 1 |
Ki = 77 nM
|
|
|
|
CP0381534
|
4-(1H-imidazol-5-yl)-N-(2-methylpropyl)butan-1-amine
Show/Hide
|
C11H21N3
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0489407
|
4-N-[2-[(2-aminopyrimidin-4-yl)-methylamino]ethyl]-6-phenylpyrimidine-2,4-diamine
Show/Hide
|
C17H20N8
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0491852
|
4-N-[2-[[2-(2-methylpropylamino)pyrimidin-4-yl]amino]ethyl]pyrimidine-2,4-diamine
Show/Hide
|
C14H22N8
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0499696
|
6-N-[2-[(2-aminopyrimidin-4-yl)amino]ethyl]-4-N-(2-methylpropyl)pyrimidine-2,4,6-triamine
Show/Hide
|
C14H23N9
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0527518
|
4-N-[2-[[2-(2-methylpropylamino)pyrimidin-4-yl]amino]ethyl]-6-phenylpyrimidine-2,4-diamine
Show/Hide
|
C20H26N8
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0921813
|
N-(amino(4,6-dimethylpyrimidin-2-ylamino)methylene)-2-(1H-imidazol-4-yl)ethanaminium
Show/Hide
|
C12H17N7
|
1
|
| 1 |
Ki = 85 nM
|
|
|
|
CP0485647
|
(4-methylpiperazin-1-yl)(4H-thieno[3,2-b]pyrrol-5-yl)methanone
Show/Hide
|
C12H15N3OS
|
1
|
| 1 |
Ki = 90 nM
|
|
|
|
CP0490644
|
(4-methylpiperazin-1-yl)(6H-thieno[2,3-b]pyrrol-5-yl)methanone
Show/Hide
|
C12H15N3OS
|
1
|
| 1 |
Ki = 90 nM
|
|
|
|
CP0419683
|
2-arylbenzimidazole derivative, 3
Show/Hide
|
C25H33ClN4O
|
1
|
| 1 |
Ki = 93 nM
|
|
|
|
CP0854866
|
ethyl[4-(1H-imidazol-4-yl)butyl]amine
Show/Hide
|
C9H17N3
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0881053
|
cyclohexyl-[4-(1H-imidazol-4-yl)-butyl]-amine tartaric acid
Show/Hide
|
C13H23N3
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0870389
|
2-[3-(Imidazol-4-yl)-propyl]-1-[2-(4-methyl-phenyl)-ethyl]-isothiourea dihydrobromide
Show/Hide
|
C16H24Br2N4S
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0060463
|
4-[(3R)-3-aminopyrrolidin-1-yl]-6-benzylpyrimidin-2-amine
Show/Hide
|
C15H19N5
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0044460
|
N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide
Show/Hide
|
C15H24N4S
|
4
|
| 1 |
Ki = 125 nM
|
|
|
| 2 |
Ki = 125.89 nM
|
|
|
| 3 |
Ki = 328 nM
|
|
|
| 4 |
Ki = 501.19 nM
|
|
|
|
CP0453280
|
VUF4904
Show/Hide
|
C11H21N3
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0846757
|
[5-(1H-imidazol-4-yl)-pentyl]-isobutyl-amine
Show/Hide
|
C12H23N3
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0541606
|
(4,6-dichloro-1H-benzoimidazol-2-yl)(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C13H14Cl2N4O
|
1
|
| 1 |
Ki = 136 nM
|
|
|
|
CP0267304
|
(6-Bromo-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C14H16BrN3O
|
1
|
| 1 |
Ki = 147 nM
|
|
|
|
CP0875456
|
[5-(1H-imidazol-4-yl)-pentyl]-propyl-amine
Show/Hide
|
C11H21N3
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0883136
|
1-[5-(1H-imidazol-4-yl)-pentyl]-azepane
Show/Hide
|
C14H25N3
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0847508
|
1-(3-(1H-imidazol-4-yl)propyl)-3-(2,2-diphenylvinyl)guanidine
Show/Hide
|
C21H23N5
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0902073
|
2-[3-(Imidazol-4-yl)-propyl]-1-[2-(4-methoxy-phenyl)-ethyl]-isothiourea dihydrobromide
Show/Hide
|
C16H24Br2N4OS
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0244889
|
4-[(3R)-3-(methylamino)pyrrolidin-1-yl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-2-amine
Show/Hide
|
C12H19N5
|
1
|
| 1 |
Ki = 159 nM
|
|
|
|
CP0783423
|
(5-Chloro-1H-indol-2-yl)-(1-methyl-piperidin-4-yl)-methanone
Show/Hide
|
C15H17ClN2O
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0875453
|
butyl-[5-(1H-imidazol-4-yl)-pentyl]-amine
Show/Hide
|
C12H23N3
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0878273
|
[4-(1H-imidazol-4-yl)-butyl]-iso-propyl-amine
Show/Hide
|
C10H19N3
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0859625
|
[amino({2-[(1Z)-4-{[4-(ethoxycarbonyl)phenyl]amino}-2-oxo-1,2-dihydronaphthalen-1-ylidene]hydrazin-1-yl})methylidene]azanium
Show/Hide
|
C20H19N5O3
|
1
|
| 1 |
Ki = 219 nM
|
|
|
|
CP0916922
|
(4-amino-1H-benzoimidazol-2-yl)(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C13H17N5O
|
1
|
| 1 |
Ki = 244 nM
|
|
|
|
CP0224451
|
1-{3-[4-(5-tert-butyl-1H-1,3-benzodiazol-2-yl)-2-chlorophenoxy]propyl}-N,N-dimethylpyrrolidin-3-amine
Show/Hide
|
C26H35ClN4O
|
1
|
| 1 |
Ki = 250 nM
|
|
|
|
CP0115845
|
4-[(3R)-3-aminopiperidin-1-yl]-6-cyclopentylpyrimidin-2-amine
Show/Hide
|
C14H23N5
|
1
|
| 1 |
Ki = 257 nM
|
|
|
|
CP0886053
|
8-chloro-11-(4-ethylpiperazin-1-yl)-dibenzo[b,f][1,4]oxazepine fumaric acid
Show/Hide
|
C23H24ClN3O5
|
1
|
| 1 |
Ki = 288.4 nM
|
|
|
|
CP0379556
|
VUF5300
Show/Hide
|
C13H23N3
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0846756
|
[4-(1H-imidazol-4-yl)-butyl]-diethyl-amine
Show/Hide
|
C11H21N3
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0881055
|
ethyl-[5-(1H-imidazol-4-yl)-pentyl]-amine
Show/Hide
|
C10H19N3
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0529668
|
N-[2-[(2-aminopyrimidin-4-yl)amino]ethyl]-5-chloro-1H-indole-2-carboxamide
Show/Hide
|
C15H15ClN6O
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0921493
|
8-chloro-11-(piperazin-1-yl)-dibenzo[b,f][1,4]oxazepin fumaric acid
Show/Hide
|
C21H20ClN3O5
|
1
|
| 1 |
Ki = 323.59 nM
|
|
|
|
CP0060462
|
4-[(3aS,6aR)-2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl]-6-cyclopentylpyrimidin-2-amine
Show/Hide
|
C15H23N5
|
1
|
| 1 |
Ki = 328 nM
|
|
|
|
CP0382716
|
4,5-dimethyl-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine
Show/Hide
|
C11H19N5
|
1
|
| 1 |
Ki = 357 nM
|
|
|
|
CP0875448
|
1-[4-(1H-imidazol-4-yl)-butyl]-piperidine
Show/Hide
|
C12H21N3
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0525312
|
4-N-[2-[(2-amino-6-phenylpyrimidin-4-yl)amino]ethyl]-6-(3-methylbutyl)pyrimidine-2,4-diamine
Show/Hide
|
C21H28N8
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0541603
|
(5-trifluoromethyl-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
Show/Hide
|
C15H16F3N3O
|
1
|
| 1 |
Ki = 412 nM
|
|
|
|
CP0469415
|
(4-methylpiperazin-1-yl)(5-trifluoromethyl-1H-benzoimidazol-2-yl)methanone
Show/Hide
|
C14H15F3N4O
|
1
|
| 1 |
Ki = 427 nM
|
|
|
|
CP0379557
|
VUF5207
Show/Hide
|
C10H19N3
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0848089
|
4-(4-pyrrolidin-1-yl-butyl)-1H-imidazole
Show/Hide
|
C11H19N3
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0878272
|
1-[4-(1H-imidazol-4-yl)-butyl]-azepane
Show/Hide
|
C13H23N3
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0525311
|
4-N-[2-[[6-(2-methylpropylamino)pyrimidin-4-yl]amino]ethyl]-6-phenylpyrimidine-2,4-diamine
Show/Hide
|
C20H26N8
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0367766
|
4-[(4aS,7aR)-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b][1,4]oxazin-6-yl]-6-cyclopentylpyrimidin-2-amine
Show/Hide
|
C15H23N5O
|
1
|
| 1 |
Ki = 520 nM
|
|
|
|
CP0540286
|
(5-methyl-1H-benzoimidazol-2-yl)(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C14H18N4O
|
1
|
| 1 |
Ki = 528 nM
|
|
|
|
CP0877509
|
[5-(1H-imidazol-4-yl)-pentyl]-diethyl-amine
Show/Hide
|
C12H23N3
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0502535
|
5-(cyclohexylmethyl)-1H-imidazole
Show/Hide
|
C10H16N2
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0510007
|
4-N-[2-[(2-amino-6-chloropyrimidin-4-yl)amino]ethyl]-6-(3-methylbutyl)pyrimidine-2,4-diamine
Show/Hide
|
C15H23ClN8
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0849116
|
tert-Butyl-[4-(1H-imidazol-4-yl)-butyl]-amine
Show/Hide
|
C11H21N3
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0862267
|
[4-(1H-imidazol-4-yl)-butyl]-dimethyl-amine
Show/Hide
|
C9H17N3
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0881157
|
4-(5-pyrrolidin-1-yl-pentyl)-1H-imidazole
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C12H21N3
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1
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| 1 |
Ki = 794.33 nM
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CP0484307
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6-chloro-2-[(1-methylpiperidin-4-ylidene)methyl]-1H-benzimidazole
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C14H16ClN3
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1
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| 1 |
Ki = 794.33 nM
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CP0456153
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4-N-[2-[(2-aminopyrimidin-4-yl)amino]ethyl]pyrimidine-2,4-diamine
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C10H14N8
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1
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| 1 |
Ki = 794.33 nM
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CP0926580
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(4Z,6E)-2,10-diamino-5,7-dimethyl-1,3,4,8,9,11-hexaazaundeca-1,4,6,10-tetraene-1,11-diium
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C7H16N8
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1
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| 1 |
Ki = 897 nM
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CP0656487
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5-Chloro-1H-benzoimidazole-2-carboxylic acid (2-dimethylamino-ethyl)-amide
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C12H15ClN4O
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1
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| 1 |
Ki = 1000 nM
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CP0489409
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4-N-[2-[(2-amino-6-phenylpyrimidin-4-yl)amino]ethyl]-6-phenylpyrimidine-2,4-diamine
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C22H22N8
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1
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| 1 |
Ki = 1000 nM
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CP0529663
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4-N-[2-[[6-(2-methylpropylamino)pyrimidin-4-yl]amino]ethyl]pyrimidine-2,4-diamine
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C14H22N8
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1
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| 1 |
Ki = 1000 nM
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CP0931203
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8-chloro-11-(4-isopropylpiperazin-1-yl)-dibenzo[b,f][1,4]oxazepine
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C20H22ClN3O
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1
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| 1 |
Ki = 1071.52 nM
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CP0896427
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[amino({[6-({[amino(iminiumyl)methyl]amino}methyl)pyridin-2-yl]methyl}amino)methylidene]azanium
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C9H15N7
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1
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| 1 |
Ki = 1240 nM
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CP0489408
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4-N-[2-[(2-aminopyrimidin-4-yl)amino]ethyl]-2-N-(2-methylpropyl)-6-phenylpyrimidine-2,4-diamine
Show/Hide
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C20H26N8
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1
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| 1 |
Ki = 1258.93 nM
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CP0525309
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N-[2-[(2-aminopyrimidin-4-yl)amino]ethyl]-1H-indole-2-carboxamide
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C15H16N6O
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1
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| 1 |
Ki = 1258.93 nM
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CP0021837
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8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
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C19H21ClN4
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1
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| 1 |
Ki = 1412.54 nM
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CP0868276
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(E)-{amino[(Z)-2-(1-{12-[(1Z)-1-(2-methylcarbamimidamidoimino)ethyl]-8-thiatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-4-yl}ethylidene)hydrazin-1-yl]methylidene}(methyl)azanium
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C20H24N8S
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1
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| 1 |
Ki = 1480 nM
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CP0527629
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6-phenyl-4-N-[2-(pyrimidin-4-ylamino)ethyl]pyrimidine-2,4-diamine
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C16H17N7
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1
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| 1 |
Ki = 1995.26 nM
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CP0055909
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8-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine(isoclothiapine)
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C18H18ClN3S
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1
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| 1 |
Ki = 2041.74 nM
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CP0529664
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4-N-[2-[(2-amino-6-chloropyrimidin-4-yl)amino]ethyl]-6-phenylpyrimidine-2,4-diamine
Show/Hide
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C16H17ClN8
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1
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| 1 |
Ki = 2511.89 nM
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CP0192798
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(5-Methoxy-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
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C15H19N3O2
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1
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| 1 |
Ki = 3000 nM
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CP0778443
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5-Chloro-1H-indole-2-carboxylic acid (2-dimethylamino-ethyl)-amide
Show/Hide
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C13H16ClN3O
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1
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| 1 |
Ki = 3162.28 nM
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CP0510009
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6-N-[2-[(2-amino-6-phenylpyrimidin-4-yl)amino]ethyl]-4-N-(2-methylpropyl)pyrimidine-2,4,6-triamine
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C20H27N9
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1
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| 1 |
Ki = 3162.28 nM
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CP0529639
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N-[2-[(2-aminopyrimidin-4-yl)amino]ethyl]-5-chloro-N-methyl-1H-indole-2-carboxamide
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C16H17ClN6O
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1
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| 1 |
Ki = 3162.28 nM
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CP0921492
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2-[4-(8-chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)-piperazin-1-yl]-ethanol
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C19H21ClN4O
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1
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| 1 |
Ki = 4677.35 nM
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CP0184119
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6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine
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C19H21N3
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1
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| 1 |
Ki = 4786.3 nM
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CP0654709
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(5-Chloro-1H-indol-2-yl)-(1-methyl-piperidin-4-yl)-methanol
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C15H19ClN2O
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1
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| 1 |
Ki = 5011.87 nM
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CP0381644
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N-[[4-[4-[(pentylamino)methyl]phenyl]phenyl]methyl]pentan-1-amine
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C24H36N2
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1
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| 1 |
Ki = 6456.54 nM
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CP0381645
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N-[[4-[4-[[cyclohexyl(methyl)amino]methyl]phenyl]phenyl]methyl]-N-methylcyclohexanamine
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C28H40N2
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1
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| 1 |
Ki = 6456.54 nM
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CP0747120
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(5-Chloro-1H-indol-2-yl)-piperidin-1-yl-methanone
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C14H15ClN2O
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1
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| 1 |
Ki = 7943.28 nM
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CP0095277
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4-(3-(4-(piperidin-1-yl)but-1-ynyl)benzyl)morpholine
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C20H28N2O
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1
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| 1 |
Ki > 10000 nM
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CP0489406
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N-[2-[(2-aminopyrimidin-4-yl)amino]ethyl]-N-methyl-1H-indole-2-carboxamide
Show/Hide
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C16H18N6O
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1
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| 1 |
Ki = 10000 nM
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CP0361358
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4-chloro-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidin-2-amine
Show/Hide
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C9H14ClN5
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1
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| 1 |
Ki > 10000 nM
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CP0361360
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4-[(3R)-3-(methylamino)pyrrolidin-1-yl]-6-(trifluoromethyl)pyrimidin-2-amine
Show/Hide
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C10H14F3N5
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1
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| 1 |
Ki > 10000 nM
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CP0428189
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1-[[4-[4-[(3,5-dimethylpiperidin-1-yl)methyl]phenyl]phenyl]methyl]-3,5-dimethylpiperidine
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C28H40N2
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1
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| 1 |
Ki = 13803.84 nM
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CP0916915
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4-Methyl-piperazine-1-carboxylic acid (5-chloro-1H-benzoimidazol-2-yl)-amide
Show/Hide
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C13H16ClN5O
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1
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| 1 |
Ki = 19952.62 nM
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CP0880524
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5-Chloro-1H-benzoimidazole-2-carboxylic acid (2-dimethylamino-ethyl)-methyl-amide
Show/Hide
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C13H17ClN4O
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1
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| 1 |
Ki = 25118.86 nM
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CP0913796
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5-Chloro-1H-indole-2-carboxylic acid (4-methyl-piperazin-1-yl)-amide
Show/Hide
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C14H17ClN4O
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1
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| 1 |
Ki = 25118.86 nM
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CP0935635
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5-Chloro-1H-indole-2-carboxylic acid (2-dimethylamino-ethyl)-methyl-amide
Show/Hide
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C14H18ClN3O
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1
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| 1 |
Ki = 25118.86 nM
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CP0203699
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1-[[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]methyl]piperidine
Show/Hide
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C24H32N2
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1
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| 1 |
Ki = 25118.86 nM
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CP0218600
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1-[[4-[4-[(1R)-1-[(2S)-2-methylpyrrolidin-1-yl]-4-phenoxybutyl]phenyl]phenyl]methyl]piperidine
Show/Hide
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C33H42N2O
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1
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| 1 |
Ki >= 31622.78 nM
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CP0387966
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1-[[4-[4-[(1R)-1-[(2S)-2-methylpyrrolidin-1-yl]pentyl]phenyl]phenyl]methyl]piperidine
Show/Hide
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C28H40N2
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1
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| 1 |
Ki >= 31622.78 nM
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CP0387969
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1-[[4-[4-[(1S)-4-(4-methoxyphenoxy)-1-[(2S)-2-methylpyrrolidin-1-yl]butyl]phenyl]phenyl]methyl]piperidine
Show/Hide
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C34H44N2O2
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1
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| 1 |
Ki >= 31622.78 nM
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CP0387972
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1-[[4-[4-[(1S)-4-methoxy-1-[(2S)-2-methylpyrrolidin-1-yl]butyl]phenyl]phenyl]methyl]piperidine
Show/Hide
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C28H40N2O
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1
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| 1 |
Ki >= 31622.78 nM
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CP0392160
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1-[[4-(4-pentylphenyl)phenyl]methyl]piperidine
Show/Hide
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C23H31N
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1
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| 1 |
Ki >= 31622.78 nM
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CP0392161
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1-[[4-[4-[[(2S)-2-methylpyrrolidin-1-yl]methyl]phenyl]phenyl]methyl]piperidine
Show/Hide
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C24H32N2
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1
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| 1 |
Ki >= 31622.78 nM
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CP0392162
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1-[[4-[4-[[(2R)-2-methylpyrrolidin-1-yl]methyl]phenyl]phenyl]methyl]piperidine
Show/Hide
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C24H32N2
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1
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| 1 |
Ki >= 31622.78 nM
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CP0395478
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1-[[4-[4-[(1S)-1-[(2R)-2-methylpyrrolidin-1-yl]pentyl]phenyl]phenyl]methyl]piperidine
Show/Hide
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C28H40N2
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1
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| 1 |
Ki >= 31622.78 nM
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CP0427547
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1-[[4-[4-[(1R)-4-methoxy-1-[(2S)-2-methylpyrrolidin-1-yl]butyl]phenyl]phenyl]methyl]piperidine
Show/Hide
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C28H40N2O
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1
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| 1 |
Ki >= 31622.78 nM
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CP0427549
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(2S)-2-methyl-1-[(1S)-1-[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]pentyl]piperidine
Show/Hide
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C29H42N2
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1
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| 1 |
Ki >= 31622.78 nM
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CP0428463
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(2S)-2-methyl-1-[(1R)-1-[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]pentyl]piperidine
Show/Hide
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C29H42N2
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1
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| 1 |
Ki >= 31622.78 nM
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CP0428596
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1-[1-[4-[4-[[(2R)-2-methylpyrrolidin-1-yl]methyl]phenyl]phenyl]-2-phenylethyl]piperidine
Show/Hide
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C31H38N2
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1
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| 1 |
Ki >= 31622.78 nM
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CP0428622
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1-[[4-[4-(2-phenyl-1-piperidin-1-ylethyl)phenyl]phenyl]methyl]piperidine
Show/Hide
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C31H38N2
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1
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| 1 |
Ki >= 31622.78 nM
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CP0428625
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1-[[4-[4-[(1S)-1-[(2S)-2-methylpyrrolidin-1-yl]pentyl]phenyl]phenyl]methyl]piperidine
Show/Hide
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C28H40N2
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1
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| 1 |
Ki >= 31622.78 nM
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CP0428627
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1-[1-[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]pentyl]piperidine
Show/Hide
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C28H40N2
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1
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| 1 |
Ki >= 31622.78 nM
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CP0432707
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N,N-dimethyl-2-phenyl-1-[4-[4-(piperidin-1-ylmethyl)phenyl]phenyl]ethanamine
Show/Hide
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C28H34N2
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1
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| 1 |
Ki >= 31622.78 nM
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CP0461873
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1-[1-[4-(4-methylphenyl)phenyl]pentyl]piperidine
Show/Hide
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C23H31N
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1
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| 1 |
Ki >= 31622.78 nM
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CP0476272
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1-[[4-[4-[(1S)-1-[(2S)-2-methylpyrrolidin-1-yl]-4-phenoxybutyl]phenyl]phenyl]methyl]piperidine
Show/Hide
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C33H42N2O
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1
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| 1 |
Ki >= 31622.78 nM
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CP0476273
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1-[[4-[4-[(1R)-1-[(2R)-2-methylpyrrolidin-1-yl]pentyl]phenyl]phenyl]methyl]piperidine
Show/Hide
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C28H40N2
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1
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| 1 |
Ki >= 31622.78 nM
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CP0495982
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1-[[4-[4-[(1R)-4-(4-methoxyphenoxy)-1-[(2S)-2-methylpyrrolidin-1-yl]butyl]phenyl]phenyl]methyl]piperidine
Show/Hide
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C34H44N2O2
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1
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| 1 |
Ki >= 31622.78 nM
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CP0005956
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1-(8-Chloro-dibenzo[b,f]oxepin-10-yl)-4-methyl-piperazine
Show/Hide
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C19H19ClN2O
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1
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| 1 |
Ki < 10000 nM
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CP0932541
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8-chloro-11-(morpholino-1-yl)-dibenzo[b,f][1,4]oxazepine
Show/Hide
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C17H16ClN3O
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1
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| 1 |
Ki < 10000 nM
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CP0949935
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8-chloro-11-piperidin-1-yl-5H-dibenzo[b,e][1,4]diazepine
Show/Hide
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C18H18ClN3
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1
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| 1 |
Ki < 10000 nM
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CP0907509
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5-Chloro-1H-indole-2-carboxylic acid (3-dimethylamino-propyl)-amide
Show/Hide
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C14H18ClN3O
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1
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| 1 |
Ki < 100000 nM
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CP0916341
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5-Chloro-1H-benzoimidazole-2-carboxylic acid (4-methyl-piperazin-1-yl)-amide
Show/Hide
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C13H16ClN5O
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1
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| 1 |
Ki < 100000 nM
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CP0916351
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[3-(5-Chloro-1H-benzoimidazol-2-yl)-phenyl]-dimethyl-amine
Show/Hide
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C15H14ClN3
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1
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| 1 |
Ki < 100000 nM
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CP0916504
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(5-Chloro-1H-indol-2-yl)-morpholin-4-yl-methanone
Show/Hide
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C13H13ClN2O2
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1
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| 1 |
Ki < 100000 nM
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CP0955358
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N-(5-Chloro-1H-benzoimidazol-2-yl)-acetamide
Show/Hide
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C9H8ClN3O
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1
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| 1 |
Ki < 100000 nM
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