Brief Information of the Compound and Protein
Compound Name
4-(1H-imidazol-4-ylmethyl)piperidine
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PubChem ID
CID: 3035842
SID: 136949843
Canonical SMILES
C(C1CCNCC1)c1cnc[nH]1
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Compound Formula C9H15N3
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 22 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 19.95 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
Ki = 19.95 nM
   TI
   LI
   LO
   TS
CL000074 SK-N-MC Homo sapiens (Human)  4
1
EC50 = 15.85 nM
   TI
   LI
   LO
   TS
2
EC50 = 56.23 nM
   TI
   LI
   LO
   TS
3
Ki = 19.95 nM
   TI
   LI
   LO
   TS
4
Ki = 21.88 nM
   TI
   LI
   LO
   TS